tumors 2 8

Tag: "tumors" at biology news

U of M researchers discover genetic key to treating deadly fungal infections

...nt." Berman also explained that some cancerous tumors contain isochromosomes, which means that the finding may yield clues about how some tumors become resistant to chemotherapy and how researchers can develop companion drugs that inhibit the de...

Mass. General study finds potential ovarian cancer stem cells

...ich may be behind the difficulty of treating these tumors with standard chemotherapy. Understanding more ab...sually appears successful, but treatment-resistant tumors recur in the vast majority of patients, leading to a five-year survival rate of less than 30 percent...

With few factors, adult cells take on character of embryonic stem cells

...f the iPS cells under the skin of mice resulted in tumors containing a variety of tissues representing the three primary types found in mammalian embryos. Those primary "germ layers" in embryos eventually give rise to all an animal's tissues and organs. Following injection into blastocysts, iPS cells also...

RNA interference stops colon cancer spread in mice

...an potentially also use them as a way to sensitize tumors and launch a combined attack that will allow us to achieve much better results with reduced side effects." ...

Radiation-armed robot rapidly destroys human lung tumors

...diation delivered by a robotic arm eradicated lung tumors in some human patients just 3-4 months after treat...n this new approach to treat lung cancer and other tumors that move during breathing. At the University of Pittsburgh, Ozhasoglu and approximately 30 collea...

Cycles of cell death, proliferation key to liver cancer

...as removed, the number and size of cancerous liver tumors decreased, and the tumors grew more slowly. Increased JNK1 activation was found in diseased liver and tumors when compared to ...

Synthetic molecule causes cancer cells to self-destruct

...s also showed that PAC-1 killed cancer cells in 23 tumors obtained from a local hospital. Cell death was correlated with the level of procaspase-3 present in the cells, with more procaspase-3 resulting in cell death at lower concentrations of PAC-1. "This is the first in what could be a host of organic co...

Speeding discovery of the 'human cancer genome'

...ajor cancers--is the strategic comparison of human tumors with those of mice. As a demonstration of the v...e fact that studies that scan the genomes of human tumors for differences typically find hundreds to thousands of genes that distinguish cancer and noncancer....

Malignant melanoma cells secrete protein required for embryo formation

...60 percent of cutaneous (skin) metastatic melanoma tumors but is absent in normal skin. They also found that blocking Nodal signaling reduced melanoma cell invasiveness, as well as cancer cell colony formation and tumor-forming ability. Strikingly, nodal inhibition promoted the reversion of these cells t...

Rice scientists make first nanoscale pH meter

...e useful in determining whether or not some cancer tumors are malignant. With current methods, a piece of the tumor would need to be physically removed via biopsy ?a painful and invasive procedure ?and visually evaluated under a microscope. Halas said LANP's new nano-pH meter could be used instead as an "op...

New human retrovirus originated in mice

...ue cells, called stromal cells, rather than in the tumors themselves. "So, one interpretation could be that the infection is entirely incidental to prostate cancer," said Ganem. "The patients with RNASEL mutations may be more likely to get the infection or perhaps less likely to clear it. Clearly XMRV is no...

Mayo Clinic study finds two genes predict outcome for breast cancer patients

... that the expression of two novel genes within the tumors of women with early stage breast cancer may allow ...ession of HOXB13 and IL17BR from paraffin-embedded tumors and found that the 2-gene expression ratio was an independent marker of early breast cancer relapse ...

The loss of a protein favors lung tumor growth

...es of lung cancer as well as in 67% percent of the tumors observed. The new Doctor in Biochemistry extracte... various cellular lines of different types of lung tumors and introduced a sequence of the protein αCP4 in order to observe the resulting effects. In some of ...

USC researchers investigate protein that protects tumors

..."We found that it was present on 60 percent of the tumors ?and it's expressed from the very first stage of the cancer formation." The next step was to determine EphB4's purpose. What the scientists discovered was that EphB4 serves as a sentry, guarding the tumor cells from any defenses the body deploys to ...

Mayo Clinic researchers discover cancer cells may move via wave stimulation

...gh binding and activating its receptor and certain tumors exhibit elevated levels of EGFR. In addition, activated EGFR have been implicated in the development and spread of several human cancers, including cancers of the colon, ovary, breast and lung. Wave Basics Waves are circular ruffled surface struc...

Biomarkers may hone anti-aging therapies

...in that was adjacent to the tumors, but not in the tumors themselves. The tumor samples were more likely to have full-length mitochondrial DNA, with point mutations rather than significant deletions, Sligh said. The mitochondrial DNA mutations in the tumor-free skin correlated with the aging process, Sligh...

Marrow-derived stem cells deliver new cytokine to kill brain tumor cells, offer protection

...uman clinical trials. Gliomas are highly invasive tumors with poorly defined borders that intermingle with healthy brain tissue, making complete surgical removal nearly impossible. Furthermore, cells separate from the main tumor and migrate to form satellites that escape treatment and often lead to recurre...

Inflammation and drugs to control this activity studied in a variety of tumors sites

...831 controls matched for age, gender and race. The tumors were analyzed by histologic type. The majority ?33...ects of antihistamines on the development of brain tumors in adults," said Scheurer. "It's apparent that some type of inflammatory response is playing some ro...

Weighting cancer drugs to make them hit tumors harder

...ht makes the drugs penetrate and accumulate inside tumors more effectively. Chemotherapy drugs often fall s...heavier molecules are more selectively absorbed by tumors because tumor blood vessels are more permeable or "leakier" than normal blood vessels. Thus, larger ...

p53, tumor suppression and aging

...sing 30-80% the normal level of Mdm2 develop fewer tumors than wild type mice, yet age normally." ...

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