tumors 2 7

Tag: "tumors" at biology news

Scientists tie several cancers to common 'oncogene engine'

.... "One would have never thought of grouping these tumors together," said David E. Fisher, MD, PhD, a pediat...mon therapeutic strategies might be applied to the tumors as well." The newly grouped cancers ?melanoma, clear cell sarcoma, alveolar soft part sarcoma, and p...

Immune system police learn early and sometimes badly

...n the pancreas and we need the ones that recognize tumors to be less frequent." The fact that most regulatory T cells in the body come directly from the thymus, not from other circulating T cells, also was previously unknown, Dr. Pacholczyk says. "Where they come from is the main question we wanted to ans...

NYU researchers decorate virus particles, showing potential to enhance MRI capabilities

... cell surfaces, we may be able to use MRI to image tumors much smaller than can currently be seen." ...

Making a face: A new and earlier marker of neural crest development

...left palate, heart valve malformations and various tumors are among the common malformations associated with disruption of neural crest development. Chick embryos have well-characterized stages and are a valuable model for examining vertebrate development. While it was known that the ability to form neur...

Coming soon: 3-D imaging that flies 'through' and 'around' cancer

...cancer, provide surgical guidance and detect which tumors may be easier to biopsy," detailed Andrew Quon, cl...ssing protocol can peel away the organs, highlight tumors and detect cancerous 'hot spots'--providing an omnipotent perspective of the body," he indicated. St...

Pak1 expression increases tamoxifen resistance in breast cancer patients

... positive breast cancer. Patients with ER-positive tumors and low levels of Pak1 had longer survival without tumor recurrence than patients who did not receive treatment. Overexpression of certain types of Pak1 was associated with decreased response to tamoxifen therapy. The authors write, "Overall, our ob...

Pathway toward gene silencing described in plants

...ental problems, from dwarfing in plants to certain tumors in humans, and death in mice. One role of DNA methylation is to turn off repetitive genes, such as transposable elements that can move or spread throughout a genome and disrupt other gene functions if left unchecked. There is also interest in DNA met...

Tumor wizardry wards off attacks from the immune system

... the fictional wizard Harry Potter, some cancerous tumors seem capable of wrapping themselves in an invisibi...f Medicine in St. Louis have found that pancreatic tumors hide from the body's immune surveillance by surrounding themselves with cells that make it hard for ...

First-ever genomic test predicts which lung cancer patients need chemotherapy to live

...o identify patterns of gene activity in individual tumors that indicate a patient is likely to suffer a recurrence of disease. Recurrent tumors are typically fatal, so identifying at-risk patients is critical to properly treating them, said the...

Combined treatment extends life expectancy for lung cancer patients

...erage life expectancy and decreases recurrences of tumors in patients who have early stages of inoperable lu... (RFA) and microwave ablation, processes that heat tumors to destroy them. For patients who cannot have surgery or radiation, the median survival is about one...

With few factors, adult cells take on character of embryonic stem cells

...f the iPS cells under the skin of mice resulted in tumors containing a variety of tissues representing the three primary types found in mammalian embryos. Those primary "germ layers" in embryos eventually give rise to all an animal's tissues and organs. Following injection into blastocysts, iPS cells also...

Study identifies new role for breast cancer susceptibility gene

... with accelerated growth and progression of breast tumors and with increased tumor blood vessel formation. I...s. Further studies demonstrated that mouse mammary tumors deficient in BRCA1 display high levels of ANG1 expression, prominent vascularization, and accelerate...

Experimental RNA-based drug kills prostate cancer cells effectively and safely

...prostate cancer, the drug shrank the size of their tumors by half, while the tumors in control mice that did not receive the drug continued to grow, said study co-author Bruce Sullenge...

Schepens scientists are first to discover angiogenesis switch inside blood vessel cells

...n a damaged heart. But, it can also nourish cancer tumors and damage delicate retinal tissues when uncontrolled. The angiogenic process is triggered by what the body perceives as a need for additional blood flow. In the case of disease, it is a mistaken need. In response, the body sends growth factors (s...

Fatty spheres loaded with siRNA shrink ovarian cancer tumors in preclinical trial

... nanometers in diameter. Blood vessels that serve tumors are more porous than normal blood vessels, with pores of 100 to 780 nanometers wide. Normal blood vessel pores are 2 nanometers or less in diameter. Second, the liposome -- a commercially available version known as DOPC -- has no electrical charge...

Scientists discover why cornea is transparent and free of blood vessels, allowing vision

...s that have undergone severe trauma or help shrink tumors fed by rapidly growing abnormal blood vessels," he says. "In fact, the next step in our work is exactly this." ...

Gene first linked to rare disease may trigger skin cancer, other tumors

...se in which patients develop multiple, benign skin tumors may be a more general player in cancers found thro...sults from the loss of a gene called CYLD, causing tumors known as cylindromas to develop in hair-follicle cells. Earlier studies indicated a role for CYLD in...

Possible birthplace of malignant brain tumors identified

...ossible treatment for the lethal, aggressive brain tumors called malignant gliomas. Arturo Alvarez-Buylla and Erica L. Jackson, of the University of California, San Francisco, and colleagues reported their findings in a paper in the July 20, 2006, Neuron, published by Cell Press. In their studies, they so...

'Signature' of chromosome instability predicts cancer outcomes

...homa). It could also differentiate between primary tumors and tumor metastases, and, in grade 1 and grade 2 breast cancer, distinguished the more aggressive cancers within each grade. ...

Buckyballs boost antibody's chemotherapy payload

...for better ways to target anticancer drugs to kill tumors without making people sick, researchers find that nanoparticles called buckyballs might be used to significantly boost the payload of drugs carried by tumor-targeting antibodies. In research due to appear in an upcoming issue of the journal Chemical...

1 2 3 4 5 6 7 8 9 10