tumors 2 6

Tag: "tumors" at biology news

Temperament linked to onset of cancer and early death in female rats

...erament and die earlier from mammary and pituitary tumors than do their more adventuresome sisters, accordin...rament among rats predicts the time at which these tumors appear and the age at which the females will die," said lead author Sonia Cavigelli, a former Univer...

Novel EGFR ectodomain mutations in glioblastoma

... in more than 100 glioblastomas. Nearly 15% of the tumors contained missense mutations—changes that altered the amino acid sequence of EGFR. But the mutations were mostly different from the ones commonly seen in other cancers: rather than changing the kinase domain, most of the gliobastoma-associated mutat...

Intrinsic eye protein halts angiogenesis

...el growth, is what propels the growth of cancerous tumors and blinding conditions like macular degeneration. Because healthy corneas are avascular (free of blood vessels) they have long been the testing grounds for anti-angiogenesis drugs intended to treat conditions in other areas of the body. The Ambati...

Cancer stem cells linked to radiation resistance

...cancer cells, called cancer stem cells, help brain tumors to buffer themselves against radiation treatment b...ls are responsible for the resistance of malignant tumors to radiation treatment," said Jeremy Rich, M.D., senior investigator of the study and an associate p...

Restoring tamoxifen sensitivity in resistant breast cancer cells

...e that were engineered to have tamoxifen-resistant tumors and saw that tumor growth was reduced by nearly 50 percent when DIBA was administered. "Exposure to DIBA causes certain physical changes to occur between the estrogen receptor and the biological machinery that stimulates cell division. By coinciden...

Gene therapy study takes aim at prostate cancer

...n itself is highly successful in eradicating local tumors (in the prostate)." The design of the study is s...ign prostate or low grade tumor but is lost as the tumors become more malignant."This characterized it as a tumor suppressor gene that is active in the prosta...

Killing brain tumors from within: A 'Trojan horse' approach

A new method for targeting malignant brain tumors through inducing the cancerous cells to "commit su...oach has been applied to mice in which human brain tumors were grown. The tests proved 100% effective in eliminating the tumorous growths. An article on t...

MIT nanoparticles may help detect, treat tumors

...neers may one day help physicians detect cancerous tumors during early stages of growth. The technique allo...w through the bloodstream and enter tumors. Solid tumors must form new blood vessels to grow. But because this growth is so rapid in cancerous tumors, there ...

Blood transfusion-transmitted infections: A global perspective

...HV-8, a virus that has the potential to cause skin tumors (Kaposi's Sarcoma) in immunocompromised recipients....

Jefferson scientists identify gene mutation potentially involved in breast cancer initiation

... that normally helps block the formation of breast tumors could play a role in the initiation of a major form of breast cancer. The team, led by cell biologist Michael P. Lisanti, M.D., Ph.D., professor of cancer biology at Jefferson Medical College and Richard Pestell, M.D., Ph.D., director of Jefferson'...

Scientist works to improve treatment for brain tumors

...n binds to it and how the biological properties of tumors may affect it. His goals in the current project ar...ll stress, is a characteristic common to all solid tumors and is known to interfere with standard therapies. Researchers aren't sure exactly what causes hypox...

Scientists resuscitate a 5 million-year-old retrovirus

...be observed in some human cancers such as germline tumors and melanomas," says Heidmann. "This work will be helpful in tracking down the role of retroviruses in these human diseases." ...

3-D ultrasound scanner could guide robotic surgeries

...rgeons could use the 3-D scanner to spot potential tumors in real time during biopsy procedures, making a diagnosis of cancer harder to miss, the engineers said. Physicians today must rely on still images, such as CT scans, of a patients' organs captured prior to biopsy to locate lesions suspected to be can...

Scientists use gene signatures to match cancer and other diseases with potentially effective drugs

..., with a mechanism by which some advanced prostate tumors continue to grow aggressively despite hormone-blocking treatments. A paper in Cancer Cell reports on this work, which made it possible for scientists to connect the action of the two natural products with known biological effects of other drugs. It t...

Major cancer study aims to identify protein markers for early-stage disease

...e interest to cancer researchers because cancerous tumors "leak" proteins and other molecules into blood, urine and other accessible bodily fluids early on in their development. This knowledge is already being applied in the clinic: Elevated levels of prostate specific antigen (PSA) hint at the presence o...

Mayo Clinic Cancer Center: Harnessing the measles virus to attack cancer

...sles virus strains can significantly shrink glioma tumors and prolong animal survival. It is very rewarding...bserved to cause regression of pre-existing cancer tumors in children. This information was noted, but nothing was done to study this phenomenon until the la...

New angiogenesis finding may help fight cancer growth

... function are also a major cause of blindness, and tumors rely on new blood vessels as they develop. Like...inhibition concerns cancer treatment. Before solid tumors start to grow, they must create a new blood supply, and since adults need angiogenesis only during p...

OHSU study says stem cell 'fusion' occurs in tumors

...ntal biology. "Second, we're seeing cell fusion in tumors and we believe that this concept is an underapprec...Although the tumor in her study did not "initiate" tumors or become malignant, Wong believes the fusion process is one explanation for how tumors acquire gene...

Einstein researchers take the pulse of a gene in living cells

...nown as "gene chips") to assess gene expression in tumors and other tissues. But with millions of cells involved, microarrays reflect only "average" gene expression. Just how a gene is transcribed in a single cell--continuously, intermittently or some other way--has largely been a mystery. Now, in observi...

Lack of key enzyme associated with development of rare tumor

...ponse to the hormone. In the study, the patients' tumors were made up of cells that were deficient in the e... the gene for PDE11A to the development of adrenal tumors was very strong, the study was not capable of proving that the mutation actually caused the tumors. ...

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