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Tag: "tumors" at biology news

Widely used iron nanoparticles exhibit toxic effects on neuronal cells

...marker molecules to make them stick selectively to tumors and other targets within the body. The particles can also be made to carry anti-cancer drugs or radioactive materials directly to a tumor. Magnetic nanoparticles designed to attach to cancerous tissue can also be made to heat up by using a remote, al...

Cancer cells forming blood vessels send their copper to the edge

...d wound healing. But it also enables the spread of tumors throughout the body, so researchers have been scrambling for ways to stop angiogenesis in the fight against cancer. One element critical to blood vessel growth is copper, a vital nutrient that plays important roles in many life processes. Compound...

New fMRI technology making brain tumor surgery safer

...ant step forward in their quest to treat difficult tumors while preserving areas of the brain that are respo...enters of the brain, allow neurosurgeons to remove tumors to the greatest extent possible without harming areas that are critical to the patient’s quality of ...

White blood cells of cancer-resistant mice overwhelm natural defenses of cancer cells

...arently have the same ability to attack a range of tumors when transplanted to ordinary mice. Cui and Willingham also want to explore how this one process can detect a wide range of cancer cells of so many different types. The dogma of cancer fighters has always postulated that there are many different c...

Stress hormones may play new role in speeding up cancer growth

... Glaser asked colleagues for samples of actual NPC tumors to look for the presence of similar receptors. The...s we can say that there is likelihood that all NPC tumors will have these receptors as well," he said. "MMP-2 and MMP-9 contribute to the aggressiveness of...

Encouraging results in pancreatic cancer research

...nistered to pancreatic tumor cells in animals, the tumors are destroyed. The research was reported in the October 1st edition of the International Journal of Cancer. Matthew R. Pincus, MD, PhD, professor of pathology at SUNY Downstate and chairman of pathology and laboratory medicine at the Brooklyn VA, s...

Stem cells engage in dialogue with the cells that regulate their futures

...intenance of tissues, while too much can result in tumors or other malignancies. Her lab used the germline stem cell niche, found in the ovaries of fruit flies, as a model system. The production of fruit fly eggs depends on the presence of a renewable source of stem cells in the ovary of the adult fruit ...

Preliminary study finds holographic imaging system promising for cancer treatment planning

...images of the body revealing the exact location of tumors in true 3D space. A study led by Rush, which al...ability to concentrate high radiation doses to the tumors while minimizing the doses to surrounding critical organs. Many of the planning tasks, such as beam ...

Science researchers genetically transform immune cells into tumor fighters

...red cells can persist in the body and shrink large tumors in humans. Two of the 17 people with advanced m... who received the experimental treatment saw their tumors shrink and were declared clinically free of disease more than a year and half after the therapy bega...

'Super' enzyme may lead way to better tumor vaccines

..."It led to the elimination of some very aggressive tumors in the mice." In the laboratory, they found tha...ver, he said, it could be modified to attack other tumors as well. ...

An AIDS-related virus tricks cells to become tumors, new Penn study finds

...their name implies, prevent or limit the growth of tumors in numerous ways. One way the tumor suppressors p53 and VHL work is to mark a key protein that controls the blood supply in a tumor mass. Once marked, this protein called hypoxia-induced factor 1a (HIF-1a) is degraded through ubiquitylation before it...

How mammals fuel milk production may have implications for cancer

...rg effect. Such increased glycolytic metabolism in tumors is associated with increased tumor aggressiveness and poor prognosis, the researchers said. “Our findings demonstrating a physiological requirement for Akt1 in the control of glucose and lipid metabolism further implicate Akt1 activation as a pote...

Natural anti-viral enzyme helps keep cancer cells alive, researchers find

...rman research team has studied clinical samples of tumors and found elevated levels of TBK-1, Dr. White said. The TBK-1 action is part of an immune reaction called the "host defense response," which is distinct from the "adaptive" immune process, in which the body creates new antibodies against invading ...

Gene signature assesses breast cancer outcomes

... group of patients 55 years or younger with breast tumors under 5 cm. The 231 genes were reduced to a core group of 70 that make up a genetic signature to predict outcomes in a separate group of patients from the same institution. To determine whether the 70-gene signature performed better than traditional...

Clue found to Epstein-Barr virus' ability to form and sustain tumors

...s the door for the development of drugs to destroy tumors caused by Epstein-Barr virus (EBV). The finding, published in the Sept. 4 Proceedings of the National Academy of Sciences Online, identifies the activity of a critical segment of a viral protein required to sustain EBV-related tumors. The researche...

Natural protein stops deadly human brain cancer in mice

...ice that got empty beads developed large malignant tumors and died. Mice with BMP4 beads survived much longer, and 80 percent survived four months after cancer cell implants. "Our idea is to treat patients with BMP4 or something like it right after surgery to remove glioblastoma in hopes of preventing th...

T-beta-RIII joins the fight against breast cancer

... and loss of T-beta-RIII was found to begin before tumors became invasive, the authors suggest that analysis of T-beta-RIII levels might help clinicians decide how aggressively to treat their patients. ...

Newly identified biomarker detects and regulates spread of brain tumors

...titute have identified a novel biomarker for brain tumors and have uncovered a potential role the marker may...d and is a predictor of patient outcome. Low-grade tumors are slow growing and show little abnormality, whereas high-grade tumors are highly abnormal and grow...

'Erectile dysfunction' drugs heighten natural anti-cancer activity

...at Hopkins on mice with implanted colon and breast tumors showed that tumor size decreased two- and threefol...drug. In mice engineered to lack an immune system, tumors were unaffected, proof of principle, the scientists say, that the drug is abetting the immune system...

Inheritance outside DNA

...inting, Feinberg found an increase in frequency of tumors in mice who also had mutations in a cancer-associated gene called Apc. In the mutant Apc mice, the loss of IGF2 imprinting seems to particularly affect the behavior of the adult stem cells that continually regenerate the colon in mice. This probably ...

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(Date:12/4/2009)By measuring the total gene activity in organs relevant for coronary artery disease (CAD), scientists at the Swedish medical university Karolinska Institutet have identified a module of genes that is
(Date:12/4/2009)Using a new mathematical model of heart cells, University of Iowa investigators have shown how activation of a critical enzyme, calmodulin kinase II (CaM kinase), disrupts the electrical activity of h
(Date:12/3/2009)Our ability to learn new information and adapt to changes in our daily environment, as well as to retain lifelong memories, appears to lie in the minute junctions where nerve cells communicate, accord
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(Date:12/4/2009)Working with mice, scientists at Johns Hopkins publishing in the December issue of Neoplasia have shown that a protein made by a gene called "Twist" may be the proverbial red flag that can accuratel
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