UCI researchers discover key factor for survival of human embryonic stem cells
...lls that are transplanted into the body often form tumors instead, causing harm to the patient. A significant challenge has been to prevent the formation of tumors by ensuring that all cells are differentiated before they are transplanted. The studies by Donovan ...Nanotechnology may find disease before it starts
... may make it possible for physicians to screen for tumors very quickly, and perhaps lessen the need for a biopsy in many cases," Liu said. Nanoparticles are smaller than any cell in the human body, so they may pass through the walls of the leaky blood vessels, or capillaries, of tumor tissue and actually i...A surprising pair of proteins help make healthy eggs
...h levels in damaged nerve tissue as well as in the tumors of certain cancers, including cancer of the skin a...n plans to extend these studies to human granulosa tumors as well as explore a possible link between TAF4b and other forms of ovarian cancer, the fourth leadi...Chemotherapy gel may fight breast cancer and reduce breast deformity
...de of a polymer substance. Mice with breast cancer tumors were treated by inserting the gel under the skin n...chemotherapy over a period of 30 days and that the tumors were completely eradicated compared to a control group of mice that were implanted with the gel inse...Researchers create pigs that produce heart-healthy omega-3 fatty acids
...itute, and his colleagues report that precancerous tumors containing a population of highly diverse cells we...o cancer. Maley suggests that genetically diverse tumors have a high probability of generating mutant cells that will flourish and spread, allowing the tumor...Evolutionary biology research techniques predict cancer
...itute, and his colleagues report that precancerous tumors containing a population of highly diverse cells we...o cancer. Maley suggests that genetically diverse tumors have a high probability of generating mutant cells that will flourish and spread, allowing the tumor...Powerful new tool for studying brain development
... 30 percent of them. Many brain disorders, such as tumors and some psychiatric diseases, are also believed t...lopment of the human brain and the origin of brain tumors from gene mutations, according to Tom Curran, Ph.D., co-chair of Developmental Neurobiology at St. J...Liver cancer linked to cellular repair pathway
...rowing body of evidence suggesting these cancerous tumors are generated by stem-like cells. Stem-like cells in the liver require the Hedgehog pathway for survival, the researchers discovered. These primitive cells are similar to stem cells, but differ in basic ways involving cell reproduction. Hedgehog may...Technique makes it easier to see mouse embryo in all its glory
...eatment of two types of childhood cancers '" brain tumors called medulloblastomas and muscle tumors called alveolar rhabdomyosarcomas. Dr. Keller, a pediatric oncologist, moved to the CCRI from the Un...'Virus chip' detects new virus in prostate tumors
...d the novel virus far more often in human prostate tumors with two copies of the RNASEL gene mutation than i...was responsible for the virus detected in prostate tumors in the study. More likely, some form of human-to-human transmission is involved, but like many intri...Source of crucial immune cell in the skin discovered
...r of the study. "Most vaccines being developed for tumors are injected into the skin and rely on these cells to transport the antigen to the lymph nodes to trigger an immune response against the tumor." Once Langerhans cells transport an antigen, they need to be replaced to maintain the tight network in th...Common molecular 'signature' identified in solid tumors
...g, breast, stomach, prostate, colon and pancreatic tumors and in the normal tissue surrounding them. Using microarray technology developed at Ohio State , lead investigators Stefano Volinia and George Calin found 137 different miRNAs expressed in at least half of the cancers, with 43 miRNAs allowing scien...Preclinical study of a new brain tumor therapy
Scientists have devised a strategy to treat tumors by selectively targeting and killing the malignant cells. A new preclinical study, published in the open access journal PLoS Medicine, has applied the approach to combat glioblastoma multiforme (GBM). This is the most aggressive form of brain tumour,...T-rays: New imaging technology spotlighted by American Chemical Society
...ogical agents through a sealed envelope and detect tumors without harmful radiation, was the focus of a recent symposium at the national meeting of the American Chemical Society. The session was organized and chaired by experts Charles A. Schmuttenmaer , professor of chemistry at Yale, and Xi-Cheng Zhan...Study shows combination of immune substances to be safe
...o treat melanoma, advanced kidney cancer and other tumors that respond poorly to chemotherapy or radiation therapy. But interferon can have serious side effects that limit its use. Surprisingly, the two drugs used in sequence caused no serious side effects in patients. "Interferon can be quite toxic whe...Mutations in the BRAF gene predict sensitivity to a novel class of cancer drugs
...ntial targeted therapy tailored for patients whose tumors contain this mutation. The researchers found that...ely inhibited the growth of cancer cells lines and tumors that have a mutated BRAF gene. One of these drugs, PD0325901 (developed by Pfizer Research and Devel...Penn researchers study the use of ultrasound for treatment of cancer
...d (about 2.5 watts), researchers observed that the tumors had little or no blood supply. "We used an ultras...that some of these newly formed vessels created by tumors are very weak in nature, and if you turn on low-intensity ultrasound vibrations you can disrupt the ...UCLA discovery will aid in treatment of patients with a deadly brain cancer
...tified key characteristics in certain deadly brain tumors that make them 51 times more likely to respond to a specific class of drugs than tumors in which the molecular signature is absent. The discovery of the telltale molecular signature ?the ...The nude mouse tale: Omega-3 fats save the life of a terminal cancer patient
...d has even gained a little weight." The cancerous tumors found in D.H.'s lungs have shrunk to 10 percent of what they were in 2000, according to last year's computed tomography (CT) scans. What worked with DH is not a common medical treatment such as chemotherapy or surgical excision. It was a nutritiona...Cancer support cells may evolve, fuel tumor growth, study shows
...uch as epithelial cells that form the bulk of many tumors including breast cancer, would be on the accumulated mutations that have allowed the cell to survive and grow unchecked. "But over the last several years, it has become increasingly clear that cancer involves complex interactions among different type...