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Tag: "tumors" at biology news

New bacterium discovered -- related to cause of trench fever

...lls. “They can cause extremely painful lesions and tumors of blood vessels on the skin of immunocompromised patients. But when I saw this patient, this type of infection had never been seen at UCSF, and the bacterium causing the infection was unknown.” Koehler’s group went on to discover that two diffe...

Study shows big power of small RNAs, not just proteins, in halting cancer

... of a previously damaged p53 pathway caused cancer tumors to stop growing and even eliminate themselves by activating an immune response in surrounding healthy cells. Most suspected that proteins would be revealed as key to the power of p53, but this latest research published June 6 by Nature now identifie...

Brightening prospects of using fluorescent nanotubes in medical applications

... for attaching the gold clusters to the surface of tumors and then exposing them to wavelengths of light that cause them to grow hot enough to destroy nearby cells. The approach has one drawback: He doesn’t have an easy way to identify the locations where the clusters attach. Nanotubes should work as well a...

Dual-imaging technique useful before -- and during -- brain surgery

... to optimize surgical approaches to treating brain tumors to ultimately improve patient outcomes.” He sa...also optimize quality of life for those with brain tumors and other neurological conditions. Leach will present this preliminary research in a special sci...

U-M researchers discover gene switched off in cancer can be turned on

...und this gene is turned off in about 15 percent of tumors studied, including cells from lung, esophageal, ovarian, bladder, colon and breast cancers. The researchers were able to use existing drugs, which showed some usefulness in turning on the BRM gene. But new drugs would need to be developed to be mo...

Progress toward an antitumor vaccine

...found a way to bind a molecule that is typical for tumors to a carrier protein without irritating the immune...antigens containing structural elements typical of tumors in the sugar as well as the protein segment,” explains Kunz, “can thus be attached to the carrier pr...

Bacteria ferry nanoparticles into cells for early diagnosis, treatment

...by inserting a cargo of fluorescent molecules into tumors that are ordinarily too small to be detected, said Demir Akin, a research assistant professor of biomedical engineering who specializes in nanomedicine. "These bacteria can potentially deliver specific molecules into a variety of cells," said Akin...

Better insight into brain anatomical structures

...In mouse brains with breast cancer metastases, the tumors were clearly highlighted by the antibody-coupled contrast agent. The same principle should allow other disease-related changes or physiological systems to be visualized by using the appropriate antibodies....

'Virtual Patient' to simulate real-time organ motions for radiation therapy

... main concern in radiation treatment or imaging of tumors that are affected by such organ movement," Xu said. "In order to determine accurate and effective radiation dosages, doctors must consider such issues as the breathing function and air volume change that are affected by several physiological factors ...

pHLIP, a novel technology to locate and treat tumors

...nstrated a new way to target and potentially treat tumors using a short piece of protein that acts like a na...gh the bloodstream and accumulated in mouse breast tumors grown to different “stages?on the leg of a mouse. The researchers demonstrated that by attaching ...

Targeting sugar on blood vessels may inhibit cancer growth

...e Medicine in UCSD’s Department of Medicine. Solid tumors need a network of blood vessels, or vasculature, i...ature, and in doing so, altered the growth rate of tumors prepared from lung carcinoma cells in the mice. "We theorized that by targeting the sugar, hepara...

Dealing deadly cancers a knockout punch

...eolysin plus gemcitabine completely eradicated the tumors in four of five test animals. It is rare to see the virtual elimination of tumours as well as the long-lasting therapeutic effect that was observed in this study. "Combination therapy results for reovirus in animals are particularly encouraging b...

Effect on breast tumors of DNA alternations in 3 genes described

...their sequence -- is one of the characteristics of tumors responsible for some of their disease properties,"...than in ER-positive tumors," said Tao. ER-positive tumors are those that express receptors for the hormone estrogen. Such tumors respond to treatments that b...

Hexavalent chromium in drinking water causes cancer in lab animals

...esearchers report finding significant increases in tumors at sites where tumors are rarely seen in laboratory animals. Male and female rats had malignant tumors in the oral cavit...

Gene thought to assist chemo may help cancer thrive

... Institute found that 70 percent of subjects whose tumors had mutations in the gene p53 were still alive aft...ugs to disable the functioning of this gene in the tumors of patients undergoing chemotherapy. The results appear in the May 16 edition of the open access jou...

Researchers wake up viruses inside tumors to image and then destroy cancers

...und a way to activate Epstein-Barr viruses inside tumors as a way to identify patients whose infection can ...-genetic imaging that doesn't require transfecting tumors with a "reporter" gene, the scientists say. "The beauty of this is that you don't have to introdu...

Investigating the measles virus as a tool to kill multiple myeloma

...y to selectively irradiate cancer cells, image the tumors and monitor regression. Eligible candidates fo...rved to cause regression of pre-existing cancerous tumors in children. This information was noted, but nothing was done to study this phenomenon until the lat...

Genetic fingerprints identify brain tumors' origins

...Cancer Center. "Our findings suggest that brain tumors arising in different regions may be genetically di...ider when trying to understand how pediatric brain tumors form." Researchers use information about tumor origins to develop new tests and treatments for th...

Scientists identify pancreatic cancer stem cells

...rding to some researchers. Thus, they remain after tumors shrink and may be responsible for cancer recurrenc...th compromised immune systems. Researchers removed tumors after they grew, and then sorted millions of cancer cells to isolate those that had one or more of t...

Gut research yields new anti-cancer approach

...ity to spread through the bloodstream to cause new tumors elsewhere (metastasize) and caused cells to self-d...ch Taxol is most used, nearly 100 percent of these tumors eventually become resistant, said Alok A. Khorana, M.D., assistant professor of Medicine at the Medi...

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