Genetic tug of war determines sexual differentiation
... a male or female is determined by the winner of a tug of war between two different genes encoding signaling proteins and the divergent pathways they control, according to a new study led by Duke University Medical Center cell biologists. In their experiments in mice, the researchers found that two spec...Molecular Motors Cooperate In Moving Cellular Cargo, Study Shows
... of steps, rather than engaging in the brute-force tug of war many scientists had imagined. "We discove...ee a fairly constant step size, we don't believe a tug of war is occurring," Selvin said. "If the dynein was fighting the kinesin, we would expect to see a...Duke Chemists Isolating Individual Molecules Of Toxic Protein In Alzheimer's, Parkinson's Disease
...cale. Pulling back the tip can induce a measurable tug on the chemical bonds that hold together the two elevated monomers. By pulling on such bonds, the Duke scientists can deduce how much energy was required to bring the molecules together. Then, using their knowledge of protein chemistry, they can dev...