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Tag: "triggered" at biology news

Mice lacking social memory molecule take bullying in stride

... his colleagues also discovered that social defeat triggered an upheaval in gene expression in the target area ...partly by interfering with the cascade of activity triggered by BDNF as the organism adapts to experience. The researchers say the study "suggests new directi...

Leave it to salmon to leave no stone unturned

... ecologists have believed that salmon nest-digging triggered only local effects. But a University of Washington researcher writes in this month's BioScience journal that the silt, minerals and nutrients that are unleashed have ecosystemwide effects, causing changes in rivers and lakes far from the nests. From...

Retinol for combating leukemia cells

...tress within the malign cells and that this stress triggered the mechanisms leading to apoptosis. This death is normally clean and programmed death, and, to this end, a group of enzymes cut the protein inside the cell at certain sites, leading to the death of the cell in question. The death has no effect on he...

Bone and cartilage growth to blame for heart valve disease

... phenomenon, but by an inflammatory process likely triggered by high cholesterol that stimulates certain cells to reprogram into bone cells in the aortic valve and cartilage cells in the mitral valve, says principal investigator Nalini Rajamannan, MD, newly appointed director of the Center for Heart Valve Dise...

Scientists identify molecular structure of key viral protein

...'s finished, spent. And you want the protein to be triggered at the right time and in the right place for fusion: when the virus binds to the cell's surface." The research team determined the pre-fusion structure by imaging crystals of the protein, using the extremely brilliant X-rays produced by the Advance...

Newly discovered killer cell fights cancer

...m the United States and France. The discovery has triggered a race among scientists to find a human equivalent of the multitasking cell, which could one day be a target for therapies that seek out and destroy cancer. "In the same way that intelligence and law enforcement agencies can face deadly threats toge...

'Prosthetic' retinal cells let blind mice see light

...echnique. "The remodeling of inner retinal neurons triggered by photoreceptor degeneration has raised some concerns for the retinal-based rescue strategy after the death of photoreceptors," wrote Pan and colleagues. "However, retinal degenerative diseases are heterogeneous as to the time course of the degenera...

Experimental drug reverses key cognitive deficits, pathology in Alzheimer's

...tors are proteins on the neuronal surface that are triggered by the chemical signals called neurotransmitters. This triggering initiates such cellular responses as the wave of electrical excitation of a nerve impulse. As an animal model of AD, the researchers used a "triple knockout" mouse in which three key...

Chocolate, wine, spicy foods may be OK for heartburn, Stanford study finds

...ept for the unlucky few whose heartburn is clearly triggered by a particular food. Gerson's advice runs counter to the long-standing recommendations of virtually every professional organization of gastroenterologists, including the American College of Gastroenterology, as well as the National Institutes of H...

How ancient whales lost their legs, got sleek and conquered the oceans

...ales lost all vestiges of the limb it was probably triggered by loss of Sonic hedgehog," said Clifford Tabin, Ph.D., a professor of genetics at Harvard Medical School who was not involved in the research. "But it's hard to say for certain because you're looking at events long after they occurred. As they sugge...

Possible birthplace of malignant brain tumors identified

...brain tissue. They also found that the receptor is triggered by PDGF in the stem cells to regulate their production of mature brain cells. The researchers located the PDGFRá-containing cells in the subventricular zone (SVZ) of the brain, which is the center for production of new brain cells in adults. The re...

Research reveals inner workings of immune system 'thermostat'

...t Interleukin 10 production by T helper 1 cells is triggered by Interferon-γ***but not directly. Another cell, an antigen presenting cell or APC, sends a stimulatory signal back to the T helper 1 cell, ordering it to make Interleukin 10. "What we see is that the 'hot' and 'cool' arms of the immune system are...

Heal thyself: Systems biology model reveals how cells avoid becoming cancerous

...cience an elaborate system of gene control that is triggered by chemical damage to DNA. "This research sheds light on the complexity of DNA repair, and offers an example of how the cellular process stimulates other pathways," said David Schwartz, director of the National Institute of Environmental Health Scie...

Schepens scientists are first to discover angiogenesis switch inside blood vessel cells

...es when uncontrolled. The angiogenic process is triggered by what the body perceives as a need for additional blood flow. In the case of disease, it is a mistaken need. In response, the body sends growth factors (such as VEGF) to blood vessels in the "needy area" to bind to receptors on the surface of the ...

H5N1 vaccine could be basis for life-saving stockpile

...will be the use of two doses, which in the ferrets triggered more antibody protection than a single dose. Immunologically naïve individuals are those whose immune systems have not been stimulated to respond to a particular antigen. The St. Jude study was the first one to show cross-reactive immunity against ...

Scientists to employ Arctic ice and polar bears to protect diversity of world's crops

...will be the use of two doses, which in the ferrets triggered more antibody protection than a single dose. Immunologically naïve individuals are those whose immune systems have not been stimulated to respond to a particular antigen. The St. Jude study was the first one to show cross-reactive immunity against ...

Flick of whiskers helps tease out brain's 'shadow' signaling system

...The chemical step is a sign that the cell has been triggered in some way and is ready to send out a signal itself. While it's been shown before that astrocytes can become activated under extreme conditions in the laboratory, Nedergaard said this is the first time that such activity has been seen in an organism...

Genetic snooze button governs timing of spring flowers

...nd his group found that exposure to prolonged cold triggered a molecular process that effectively silenced the genes that repress flowering. Another processes known as bud dormancy, which is similar to vernalization, occurs in many plants that grow in temperate climates. "Bud dormancy is not broken until the...

Movie spies on malaria parasite's sneaky behavior

...c symptoms of malaria ?high fevers and chills ?are triggered in people who are infected. Ménard and Amino collaborated with Volker Heussler at the Bernhard-Nocht Institute for Tropical Medicine in Hamburg, Germany. Their images of the parasite sneaking back into the host's bloodstream--published in advance o...

Higher risk for cervical cancer seen among women infected with multiple HPV types

..., the current test cannot determine whether it was triggered by just one genotype or multiple types of HPV. Because the HPV test used by Franco and his colleagues could detect more than 40 types of the virus and the presence of multiple infections, they could determine the specific genotypes of HPV present ...

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