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Tag: "triggered" at biology news

A gene's first 'kiss' sets off that affair known as puberty

...reproductive years as men and women, appears to be triggered by the brain's own version of "It takes two to tango," whereby a signal literally gets turned on by a molecule that is produced by a gene aptly named KiSS-1. The couple ?a biochemical equivalent to Adam and Eve ?makes its sudden appearance in a regi...

Scientists ID molecular 'switch' in liver that triggers harmful effects of saturated and trans fats

...fats. The research also showed that when the fats triggered PGC-1beta, the co-activator interacted physically and turned up the function of sterol responsive element binding proteins. These important parts of the mechanism activate many key genes of lipid biosynthesis involving the pathways of cholesterol and...

UCSB scientists probe sea floor venting to gain understanding of early life on Earth

...hermal venting occurs in frequent bursts, possibly triggered by earthquakes," said Haymon. "Such widespread and oft-repeated pulses of hydrothermal venting may stimulate microbial blooms on abyssal hill fault scarps, thus providing a potential food source for ridge flank biota, and an opportunity for researche...

Plants respond similarly to signals from friends, enemies

...erasinghe first observed the changes in the plants triggered by signals from rhizobia, called Nod factors, and then saw the similar changes occurring when plants were signaled by root-knot nematodes. In the paper, the researchers call the nematodes' signals "Nematode factors." After rhizobia perceive plant si...

Gene therapy converts dead bone graft to new, living tissue

...cture. This process of teardown and rebuilding is triggered in the dead bone when Schwarz paints it with the genetically modified virus. New blood vessels begin to grow around and into the bone splint, stripping it down in times when the body needs the calcium, and rebuilding it when calcium levels rise. The ...

Taking Aim With Nanoparticle PEBBLEs

...ers to deliver a deadly cargo to cancer cells when triggered by exposure to light. Unlike chemotherapy drugs that attack tumors by invading cancer cells and disrupting their DNA, PEBBLEs never enter the cells they target. Instead, they attach to the outside of the targeted cell and shoot reactive oxygen speci...

Genetically modified natural killer immune cells attack, kill leukemia cells

...n10,000 times their original number. The technique triggered growth of NK cells specifically, which greatly simplified the ability of the researchers to collect a pure population of these immune cells. The researchers then genetically modified the growing NK cells so they carried on their surface an artificia...

First real-time view of developing neurons reveals surprises, say Stanford researchers

... activity. Moving the square the reverse direction triggered a different population of neurons to light up. "At first we felt like we let some air out of our own tires with this finding," said Smith. His previous work had supported the prevailing idea that neurons need a period of fine-tuning before establish...

New research indicates a 'troubled' greenhouse is brewing

...is a danger that another similar outburst could be triggered by warming of polar and submarine ice due to human activities. Our little warming push could repeat the troubled times of 55 million years ago." However, Retallack says these findings indicate it is unlikely that super storms will freeze North Ameri...

Scientists solve structure of key protein in innate immune response

...n often fatal systemic bacterial infection that is triggered by LPS. "Pharmaceutical companies have tried to develop anti-septic shock agents for a long time without clear success," explains Dr. Lee. "Since LPS is an important inducer of septic shock, blocking LPS receptors such as CD14 are among the most imp...

Family trees of ancient bacteria reveal evolutionary moves

... relying on geological events for transitions that triggered change, but I'm arguing that a lot of these things could be evolutionary." Blank presented her research at the 2004 annual meeting of the Geological Society of America, held, Nov. 7-10 in Denver. Blank's finding that Cyanobacteria emerged first in f...

Camera Traps Catch Eye of the Tiger

...o set up camera traps, armed with infrared sensors triggered by movement. WWF put 30 camera traps in the forests -- one per tiger home range (about 40 square miles) -- and checks them every 3-4 weeks. Because the cameras have been placed in remote locations, it takes at least a day to hike to each (the team c...

Genetically Modified Natural Killer Immune Cells Attack, Kill Leukemia Cells

...n10,000 times their original number. The technique triggered growth of NK cells specifically, which greatly simplified the ability of the researchers to collect a pure population of these immune cells. The researchers then genetically modified the growing NK cells so they carried on their surface an artificia...

Decoding the logic of olfaction

... to investigate the patterns of activity that were triggered by a range of odorants in the olfactory cortex of mice. "We wanted to find out whether inputs from receptors that recognized the same odorant are all targeted to the same places in the cortex, producing a distinctive spatial map for the odorant," sh...

Genpathway and Baylor College of Medicine Identify New Genes in Breast Cancer

... to investigate the patterns of activity that were triggered by a range of odorants in the olfactory cortex of mice. "We wanted to find out whether inputs from receptors that recognized the same odorant are all targeted to the same places in the cortex, producing a distinctive spatial map for the odorant," sh...

Structure-building cell signals also may influence learning and memory

...ts EphB receptor, a cascading chemical pathway was triggered that ultimately stimulated an enzyme called synaptojanin-1. This enzyme is essential for a process known as cellular endocytosis, whereby certain chemicals, viruses or other agents are surrounded with a snippet of the cell's membrane. Endocytosis imp...

Researchers find gene that may be at root of potato blight

...n their Avr3a gene escaped the resistance response triggered by R3a. Further laboratory analysis showed that when R3a detected Avr3a in a leaf cell, that plant cell died. "This programmed cell death is how the plant keeps the pathogen from spreading to other cells," Kamoun said. "Only a few cells die. It's o...

Remote control flies? Fly behavior controlled by laser light

... To accomplish this, Miesenböck and Lima devised a triggered molecular lock and key system, where the "lock" wa...d changing their flight paths. Misenböck says the triggered behaviors can last seconds or continue for minutes, depending on whether the neural circuit activate...

Primates on the brink

...mber tsunamis that devastated coastal Sumatra have triggered a possible new threat to orangutan habitat from resettlement of area residents. Changes to the list from 2002 reflect a desire to draw attention to other endangered primates. For example, Miss Waldron's red colobus, which has gone decades without a ...

Studies reveal how plague disables immune system, and how to exploit the process to make a vaccine

...version rV10, missing amino acids 271 through 300, triggered only small amounts of IL-10 and had little effect on TNF secretion. Mice immunized twice over six weeks with rV10 developed antibodies that protected them from many times the lethal dose of the bacteria. "Our data, the authors conclude, "provide the...

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