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Tag: "trials" at biology news

Researchers discover how tumor suppressor gene works

...has been filed. Dong said he hopes to see clinical trials of this or similar treatments begin in a few years. ...

Results of world's first gene therapy trial for arthritis show approach safe, feasible

... investigators hope to conduct additional clinical trials in both osteoarthritis and rheumatoid arthritis using AAV to transport the gene. In addition to Drs. Evans and Robbins, other authors are James H. Herndon, M.D., also now at Harvard; Steven C. Ghivizzani, Ph.D., now at the University of Florida; Mar...

Researchers report breakthrough against world’s deadliest viruses

...rburg viruses. Following extensive work, including trials with mice and guinea pigs, the PHAC researchers collaborated with USAMRIID to prove their efficacy in non-human primates. Canadian Health Minister Ujjal Dosanjh and Dr. Carolyn Bennett, Minister of State (Public Health), praised the work of the scie...

Researchers develop gene therapy to reverse pulmonary arterial hypertension

...y, newer drugs that inhibit Survivin, currently in trials in oncology, might also be directly applicable to PAH patients, Dr. Michelakis explains. The researchers are supported by the Canadian Institutes of Health Research and Canada Research Chair Program, the Alberta Heart and Stroke Foundation, the Albe...

Solution to 'legionella'

...ly-isolated laboratory (P2 level). A wide range of trials were carried out in this isolated and secure system in order to determine the efficacy thereof. Regarding the technology developed, it consists of a system based on low-intensity, high-frequency ultrasounds which, together with the introduction of m...

Experimental shingles vaccine proves effective in nationwide study

In one of the largest adult vaccine clinical trials ever, researchers have found that an experimental vaccine against shingles (zoster vaccine) prevented about half of cases of shingles--a painful nerve and skin infection--and dramatically reduced its severity and complications in vaccinated persons w...

Survey Uncovers Surprising Attitudes Towards HIV Vaccine Research

...required for the more than 30 HIV vaccine clinical trials currently planned or under way,?says NIAID directo...uci, M.D. “It is essential that current and future trials involve volunteers from diverse communities to enable us to find a vaccine that works for all popula...

Nanotechnology to provide portable genetic risk detection

...d reused for other applications. After evaluation trials later this year, a commercial variant of the system is likely to be produced within one or two years by Sensia, a 15-month-old spin-off company from the CNM. ...

Old drug shows new promise for Huntington's Disease

..., noted Massa, the doses given in current clinical trials are much smaller than were commonly prescribed in Japan. In addition, he explained, it has been found that vitamin B12, when taken along with the drug, protects against its potential toxic effects. Co-authors of the study were Trent Nguyen, PhD, and...

Tiny roundworm's telomeres help scientists to tease apart different types of aging

...e roundworm Caenorhabditis elegans succumbs to the trials of old age although its telomeres are still long, and moves with a youthful spring in its crawl despite short telomeres, they report in PLoS Genetics, available online now. In the past, preventing telomere shortening has often been portrayed as the ...

Grand Challenges in Global Health initiative funds Yale project

...infectious agent. These cannot be studied in human trials unless researchers are confident that they are safe. "A big need in the world of vaccine development is the ability to predict whether vaccines for humans are safe and effective," said Flavell. "We are grateful to the Grand Challenges in Global Heal...

Bone marrow stem cells may heal hearts even years after heart attacks

...ine-University in D�sseldorf, Germany. If further trials produce similar results, cardiac regeneration usin...f the positive results," Dr. Strauer said. Larger trials are already underway. Meanwhile, researchers continue to refine the techniques for harvesting, proce...

Gene therapy reverses genetic mutation responsible for heart failure in muscular dystrophy

... Dr. Xiao cautioned, however, that human clinical trials of this therapy face several major challenges. Foremost is that effective treatment requires the injection of a large amount of the virus so there is enough to reach every muscle cell. Because 30 percent to 40 percent of the population has antibodies...

Many smokers fail to quit after cancer diagnosis

...ing cessation among cancer patients" and treatment trials should "include patients with non-smoking-related cancers." The authors conclude: "cancer patients who are able to stop smoking and remain abstinent after diagnosis and treatment are likely to reap substantial physical and psychological benefits, inc...

PLoS Medicine publishes first trial of effect of male circumcision on HIV infection

...ve effect is a randomized intervention study. Such trials are under way in Uganda and in Kenya but the trial reported in PLoS Medicine is the first to be completed, peer-reviewed, and published in a medical journal. The large protective effect of male circumcision observed has surprised many HIV experts, ...

Anti-cancer Compound In Beer Gaining Interest

...flashes" and osteoporosis - but no proper clinical trials have been done to study this. Information about these compounds appears to be spreading. Hop-containing herbal preparations are already being marketed for breast enlargement in women, the OSU research report said, without waiting for tests to verify...

Living anti-HIV gel shows early promise

...re and distribute. But they add that before human trials can begin, researchers will need to ensure that th...e approach has produced promising results in mice, trials on monkeys exposed to HIV or the primate equivalent (SIV) will have to be successful before the bact...

Kenya halts first field trials of GM maize

...etback to Kenyan research, but that GM maize field trials would continue. "This is just like a battle we lo...in open fields ( see Kenya begins first open field trials of GM maize ). The IRMA researchers had hoped to release the maize to farmers by 2010 ( see Revision...

Careless reporting on HIV 'could cost lives'

...ays that media reports were partly responsible for trials of the HIV drug tenofovir being cancelled in Cambo...s found that media reports about opposition to the trials varied greatly, and some were "entirely incorrect". Some reports said opposition grew because trial...

University of Delaware researchers develop cancer 'nanobomb'

...would take extensive testing and years of clinical trials before the nanobombs could actually be used in medical applications to treat human beings. "Make no mistake, we are focused on eradicating cancer," Panchapakesan said, explaining that the nanobombs are the result of work over the past two years wi...

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