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Tag: "trials" at biology news

Moffitt-USF head toward first human trials of anti-cancer drug that targets protein AKT

...eenwich Therapeutics Inc. and is planning clinical trials with Moffitt. The trials are expected to start within six to eight months. Patients will be selected for the trials based on ...

New study: Sexually transmitted disease treatment can be effectively administered by sex partners

...he partners have side effects. In three randomized trials [on patient-delivered partner treatment] that have been conducted, there have been no reports of adverse events," Dr. Kissinger said. "Particularly for chlamydia, there is little chance of side effects with azithromycin," the antibiotic given to pati...

Measurement Challenges In Detecting Cancer Biomarkers

...he partners have side effects. In three randomized trials [on patient-delivered partner treatment] that have been conducted, there have been no reports of adverse events," Dr. Kissinger said. "Particularly for chlamydia, there is little chance of side effects with azithromycin," the antibiotic given to pati...

Fragile US vaccine system needs improvement despite dramatic gains in health over past century

...from two to twenty-one years from Phase I clinical trials to licensing. Safety concerns, such as the problem with the rotavirus vaccine in 1998 as well as unfounded and unproven concerns about other vaccines threaten to lead to decreased vaccine coverage and outbreaks of vaccine-preventable infectious dise...

New Finding May Aid Adult Stem Cell Collection

...he partners have side effects. In three randomized trials [on patient-delivered partner treatment] that have been conducted, there have been no reports of adverse events," Dr. Kissinger said. "Particularly for chlamydia, there is little chance of side effects with azithromycin," the antibiotic given to pati...

Newest HIV drugs should be used with FUZEON(R)

...mbination with FUZEON RESIST Phase III tipranavir trials Over 24 weeks, almost double the proportion of pat...not receiving FUZEON POWER Phase II TMC114 dosing trials Over 24 weeks in the combined TMC114 trials, almost double the proportion of patients who received F...

Morphine for Chest Pain Increases Death Risk

...he study's lead author. "Since randomized clinical trials evaluating the safety or effectiveness of morphine for these patients have not been conducted, official guidelines for its use are based solely on expert conjecture. Given the adverse outcomes associated with morphine use found in our analysis, a ran...

Mechanism for the captation of nutrients in plants- unknown to date

...able of initiating endocitosis, given that, in the trials undertaken with substances similar to saccharose, such as glucose or fructose, the fact that none of these triggered the process could be confirmed. Moreover, given that endocitosis is involved in the acquisition of substances for their subsequent c...

Diabetic nerve therapy shows 'striking' results

...tion in California and the first phase of clinical trials has now begun. An estimated 50 per cent of patien...gramme into the clinic. "The first phase of human trials will assess safety and examine the effects of a single treatment in one leg compared with a placebo ...

New method shows it is possible to grow bone for grafts within a patient's body

...proceed with the large animal studies and clinical trials necessary to determine if the procedure will work in humans and, if it does, to get it approved for human treatment. At the same time, they hope to test the approach with the liver and pancreas, which have outer layers similar to the periosteum. ...

It's electric: Cows show promise as powerplants

...ndigested through a cow. "We've run some of these trials well over 30 days without a decrease in the voltage output," Christy said. "Both studies suggest that cow waste is a promising fuel source. It's cheap and plentiful, and it may someday be a useful source of sustainable energy in developing parts of t...

Using nanoparticles, in vivo gene therapy activates brain stem cells

...ential to revert back to wild-type, and some human trials have even resulted in fatalities. As a result, new research focuses increasingly on non-viral vectors, which don't carry this risk. Viral vectors can be produced only by specialists under rigidly controlled laboratory conditions. By contrast, the n...

New vaccine protects more effectively against tuberculosis

...ne Projekt Management who will test it in clinical trials early 2006. The responsible mechanisms for the high efficacy of this vaccine has now been deciphered (Journal of Clinical Investigations, August 18, 2005). Globally, tuberculosis remains the number one killer in adults. Moreover, multi-drug-resista...

Discoveries by UAB and Florida scientists may help transplanted organs survive longer

...y could ?after more research and possible clinical trials in human beings ?offer the benefit of at least sev...imates ?and if successful there, go on to clinical trials in humans, said Agarwal. ...

Unexpected lock and key mechanism found for the assembly of tumor blood vessels

.... They are also currently planning cancer clinical trials with an FDA approved drug directed against the int...ies to test integrin inhibitors in cancer clinical trials at the new Moores UCSD Cancer Center. Varner's colleagues in the study included Barbara Garmy-Susin...

Improving the potential of cancer vaccines

...-tumor immunity," he said. He hopes that clinical trials with these special ligands in patients with cancer can get underway quickly. "It could have a huge impact on cancer therapy or treatment of infectious disease," said Wang. "It could boost response to cancer vaccine as well." ...

Study shows how retinoic acid enters a cell's nucleus

...A can inhibit tumor growth. In fact, past clinical trials have shown that RA can help treat leukemia, head, neck and breast cancer. RA and its synthetic derivatives may also be useful in treatment of diabetes, arteriosclerosis and emphysema. Unfortunately, conventional treatments using RA require high, toxi...

Doctors should stop prescribing antibiotics for the common cold, review advises

...g both the content and quality of existing medical trials on a topic. Arroll reviewed 12 trials that included more than 1,900 patients with symptoms lasting for seven days or less or with colds th...

New type of rejection blocker protects kidneys after transplant

...loped belatacept, is conducting phase III clinical trials of the drug for kidney transplants. UCSF also is participating in that trial. RESEARCH RESULTS Belatacept is an injectable protein, one of a group of experimental drugs called co-stimulatory blockers. The immune system's normal response to a tran...

Hepatitis C responds best to combo of ribavirin and interferon, study concludes

... response. The researchers reviewed 72 randomized trials and 9,991 patients who had chronic hepatitis C for...g both the content and quality of existing medical trials on a topic. Hepatitis C is inflammation of the liver caused by the hepatitis C virus (HCV). It is t...

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