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Tag: "trials" at biology news

Nanoparticles offer new hope for detection and treatment

...s and therapy in humans will be tested in clinical trials in about one and a half to two years. The spherical nanoparticles are a few thousand times smaller than the dot above this "i," yet each can carry about 100,000 molecules of the metal used to provide contrast in MRI images. This creates a high densi...

Buying Time Through Hibernation on Demand

...it on a dime." Roth anticipates that such clinical trials in humans could be under way within about five years. The National Institutes of Health and Fred Hutchinson Cancer Research Center funded this research. ...

Anti cancer virotherapy well tolerated in first human administration, research finds

...preclinical stage, progressing to Phase I clinical trials in 2005. Initial clinical trials will be on melanoma and ovarian cancer. More information is available at www.psiron.com ...

U-M team recovers ancient whale in Egyptian desert

...it on a dime." Roth anticipates that such clinical trials in humans could be under way within about five years. The National Institutes of Health and Fred Hutchinson Cancer Research Center funded this research. ...

Test for early detection of prostate cancer shows promise

... biopsy, according to Getzenberg. Larger clinical trials are under way to further refine the EPCA test, to make it more sensitive so it can pick up even the smallest traces of the marker, and to verify its usefulness for detecting prostate cancer in a larger sample of patients, said Getzenberg. Prostate c...

Roche clinical trial registry and results database launched

...w.roche-trials.com information on Roche’s clinical trials can be accessed by anyone, anywhere, with no passw...and results from all Phase II to Phase IV clinical trials completed after 1 October, 2004. In addition, data from all Phase II to Phase IV clinical trials for...

FDA Works To Speed The Advent Of New, More Effective Personalized Medicines

... focus on integrating pharmacogenomics in clinical trials for new drugs, biologics, and associated devices. FDA will also address ways to translate pharmacogenomics into medical product development and clinical practice. On April 26th at 1:00 p.m. at the Washington Convention Center , the FDA will be prese...

Chromosome Deletion Predicts Aggressive Neuroblastoma

...nical research organization that supports clinical trials for pediatric cancer patients. Neuroblastoma, which accounts for 10 percent of all pediatric cancers, often occurs as a solid tumor in a child's abdomen or chest. Some cases of neuroblastoma are low risk, and resolve after surgeons remove the tumor....

Researchers find promising cancer-fighting power of synthetic cell-signaling molecule

...be a new approach to treat cancer." However, human trials must still be done to determine safety and efficac...rticularly useful if Enigmols enter human clinical trials because the patients will have undergone, and will probably be undergoing, other treatments anyway, ...

NIAID begins clinical trial of West Nile virus vaccine

...S, Ebola and SARS also are being tested in ongoing trials at NIH. Fifteen healthy volunteers between the ages of 18 and 50 will receive three injections of the DNA vaccine into the upper arm: one at the start of the trial, a second approximately four weeks later, and a third approximately four weeks after ...

Genetic therapy reverses nervous system damage in animal model of inherited human disease

...r findings, the researchers note that any clinical trials in humans might be years in the future. ### Video comparing a cat with AMD to one that had been given gene therapy is available at www.mrw.interscience.wiley.com/suppmat/0364-5134/suppmat/2005/57/v57.3.355.html. ...

Bevacizumab Combined With Chemotherapy Improves Progression-Free Survival for Patients With Advanced Breast Cancer

...ounding tissue to a solid tumor. “Recent clinical trials have shown that anti-angiogenic drugs have a favor...aid JoAnne Zujewski, M.D., who heads breast cancer trials for NCI’s Cancer Therapy Evaluation Program. “It is fortunate that ECOG, assisted by multiple other ...

Secret of smallpox's success may lead to bioterror cure

...vaccine cannot actually be tested through clinical trials on humans. Instead, the vaccine is tested on mice and other animal models, using viruses closely related to smallpox that are lethal to those animals. "We're testing with vaccinia and mousepox in lab mice, and in dormice with monkeypox. These are go...

Supercomputers to focus brains on AIDS dilemma

...of these compounds is expected to go into clinical trials this year, with UCSD as one of the trial sites. The Merck scientists have chosen a drug development strategy in which they are developing "single wing" compounds, whose wings, or cyclic moieties, can bind to either the west or the east in the integr...

Science study holds implications for gene therapy and stem cell biology

... are also being tested in well-controlled clinical trials to treat severe inborn diseases or cancer in humans. Retrovirus-based gene transfer vectors are partially defective retroviruses that integrate into the genome of a cell, thus potentially increasing the activity of neighboring genes. A previous stu...

Stealth Worms May Improve Insect Pest Control

... collecting native species of EPN for pest control trials in citrus and iceberg lettuce, with funding from the Arizona Citrus Research Council and the Arizona Iceberg Lettuce Research Council. Ninety percent of the citrus orchards in the state have the parasitic citrus nematode. "We're looking for options ...

Thai spice helps cut blood sugar swings

...e followed by weight loss, but no controlled human trials have shown either effect. Nevertheless, many people seem to believe HCA will help them lose weight. It's sold by vitamin and other specialty shops as Citrimax or Citrin, and is a featured ingredient in such dietetic aids as Herbalife's "Snack Defense...

Asymptomatic HIV babies could use earlier treatment

...g to be appropriate for everyone.?/p> Clinical trials are needed to determine if every infected newborn should be treated or if some subsets of infants will benefit more than others, Maldonado explained. In the meantime, the findings emphasize the importance of testing pregnant women for HIV and watchin...

New miniaturised chip dramatically reduces time taken for DNA analysis

... production techniques, to just thirty minutes. In trials developed with the support of the UAB's Department of Genetics and Microbiology, the new sensors have enabled Salmonella to be identified in four and a half hours, compared to three to five days using the traditional microbiological methods. This met...

Does vitamin C help prevent or treat the common cold? Maybe not, after all.

...t for an established cold? The authors found seven trials (all in adults) evaluating whether vitamin C taken when their symptoms started would shorten the cold. When they looked at all seven studies together, they found no benefit from taking the vitamin. But in one of the seven trials, patients took a sing...

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