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Tag: "trials" at biology news

T cells activated to fight HIV basis for dendritic cell therapeutic vaccine

...dendritic cells provides a basis for immunotherapy trials of persons with HIV infection," said Dr. Huang. The trial should be enrolling patients within the year, pending approval by the U.S. Food and Drug Administration. The researchers have already completed a similar trial in 18 patients that proved the...

Protein-coated dental implants could improve bone regeneration

...ation of gum tissues." The next step is clinical trials of an implant coated with the proteins, which Dr. Wikesjö hopes to start this summer. "There are still things we need to learn. In some cases, the protein may rapidly release from the implant, and other times, there appears to be a more gradual re...

Natural pine bark extract relieves muscle cramp and pain in athletes and diabetics

...nstrated its anti-inflammatory effects in clinical trials for asthma, dysmenorrhea and osteoarthritis. ...

Defense peptide found in primates may block some human HIV transmissions

...y tests would need to be completed before clinical trials could begin no earlier than 2009. Cole's findings were published in the June 1 issue of The Journal of Immunology, a top journal in the fields of immunology, molecular biology and microbiology. ...

Allergy battle could be won in five years, says scientist

... advanced and potential drugs could enter clinical trials as early as 2010. If successful, the drug would treat established symptoms already found in adult sufferers and, in due course, could be used to prevent allergies in children. "Prevention of allergies has never before been possible," said Profess...

Study shows pine bark naturally decreases severe chronic venous insufficiency

...trated its efficacy and safety in several clinical trials and symptoms of CVI have been reduced significantly by Pycnogenol® in controlled studies. We were pleased to see that not only did Pycnogenol® decrease CVI symptoms, but the results were significantly more successful then the prescription drug used f...

New bird flu drug promises to beat the problem of resistance

...oblems as current treatments should begin clinical trials within the next three years, thanks to a new resea...e molecules at the University of Bath, the initial trials on the influenza virus will be carried out by Dr Mckimm-Breschkin at CSIRO in Melbourne. CSIRO was...

Smell of success for nanobiosensors

...igh degree of accuracy. Some of the results of the trials surpassed even our expectations," Samitier says. These tiny bioelectronic sensors, he says, represent a 'major leap forward' in smell technology and a clear example of a biomimetic devices obtained by converging Nano-Bio-Info technologies. Several h...

Hopkins scientists show hallucinogen in mushrooms creates universal 'mystical' experience

...th them during the capsule-taking sessions. Actual trials took place in a room outfitted like a comfortable, slightly upscale living room, with soft music and indirect, non-laboratory lighting. Heart rate and blood pressure were measured throughout. The researchers countered "expectancy" by having both mo...

Experimental vaccine protects lab animals against several strains of H5N1

...s-reactive to various H5N1 viruses. Human clinical trials have seen similar results, suggesting that two doses of vaccine will be required to effectively protect against an H5N1 flu strain. In an accompanying editorial, Alan W. Hampson, MSc, of the Australian Influenza Specialist Group, noted that the succ...

A sweet solution for Alzheimer's disease?

... Therapeutics has regulatory approval for clinical trials of scyllo-inositol in humans with Alzheimer's disease and started them about a week ago. St George-Hyslop has a small financial interest in the company. St George-Hyslop and his colleagues are optimistic that scyllo-inositol will be less toxic to ...

Compound in dairy products targets diabetes

...t metabolism," says Vanden Heuvel. Early human trials indicate that when administered for longer than 8 weeks, CLA improves the body's misregulation of insulin and lowers the level of glucose in the blood in patients with adult onset, or Type-2 diabetes, the most common form of this disease. Howev...

UCLA study finds same genes act differently in males and females

...tion dosages for women have been based on clinical trials primarily conducted on men. "This research represents a significant step forward in deepening our understanding of gender-based differences in medicine," said Dr. Janet Pregler, director of the Iris Cantor-UCLA Women's Health Center. The center's e...

Scientists tie several cancers to common 'oncogene engine'

...s are already using these new insights in clinical trials of a cancer vaccine, GVAX, that previously has produced rare but dramatic responses in some patients with advanced melanoma. "We have just opened a trial to offer the same vaccine to patients with all of the other cancers in this related family," sai...

AIDS vaccine research offers new insights on survival

... samples taken from participants in human clinical trials [to test the AIDS vaccine] scientists would be able to predict how well the vaccine would work over time." More than 30 million individuals -- a majority in the world's developing nations -- have died of AIDS since it was first identified 25 year...

Trials for new drug to overcome HIV

...which is developing PA-457. Panacos hopes to begin trials this month to test how well the drug works in pati...ividual patients, though Allaway warns that larger trials are needed and PA-457 will not reach the market until 2009 at the earliest. Other HIV researchers a...

'Smart' genetic therapy helps the body to heal itself

...ave to be followed up by Phase II and III clinical trials in SMA patients," she said, "but unfortunately, th...erest from the pharmaceutical industry in clinical trials for rare disorders. However, the long-term outcome could be both improved therapy to enable a bett...

Liquorice cancer care

... as liver targeting carriers,' says Yuan. Clinical trials are planned for the near future. In addition, glycerrhizic acid is tens of thousands of times cheaper and easier to isolate than the antibodies usually used. Tim Meyer, Consultant Medical Oncologist at the Royal Free Hospital London agrees, that ti...

Combination therapy shows promising results in patients with advanced lung cancer

...tempt to define an optimal biological dose. Larger trials of combination therapies utilizing this dose will now be required." The biology of an individual's tumor determines whether they will respond to Tarceva. Because researchers don't yet fully understand what biologic characteristics determine response...

Gene transfer using mutant form of good cholesterol cuts vascular plaque and inflammation

...d animal studies at Cedars-Sinai that led to human trials at the Cleveland Clinic in which intravenous injections were found to shrink plaque in human coronary arteries. The Cedars-Sinai researchers, collaborating with researchers from Sweden, also are developing vaccine against LDL cholesterol (bad chol...

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