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Tag: "trial" at biology news

Compound from marine bacteria shows potential as multiple myeloma therapy

...his study and will be leading the Phase-I clinical trial in myeloma at Dana-Farber. NPI-0052 was discovered by William Fenical, PhD, and his collaborators at The Scripps Institute of Oceanography during the fermentation of Salinispora, a new class of marine gram-positive bacteria identified in sediment sa...

Cells from amniotic fluid used to tissue-engineer a new trachea

...eviewing Fauza's application to conduct a clinical trial in human babies with a prenatal ultrasound diagnosis of CDH; the amniotic fluid would be collected several months before birth and a tissue-engineered patch made ready for use soon after delivery. His team is also working on stem-cell-based, tissue-e...

Clinical trial to test stem cell approach for children with brain injury

A unique clinical trial will gauge the safety and potential of treating ch...orial Hermann Children's Hospital. The clinical trial is the first to apply stem cells to treat traumatic brain injury. It does not involve embryonic ste...

Stroke treatment a step closer after trial

..., have now reported the results of the first small trial of IL-1ra in patients, which are published in the ...n the University's Faculty of Life Sciences. "The trial was a definite step in the right direction and may lead to a full trial to test its effectiveness ne...

Magnetic probe successfully tracks implanted cells in cancer patients

... injection in large animals. The current clinical trial builds on Bulte's earlier work tracking magnetically labeled cells in animals. Four years ago, he and colleagues reported that stem cells containing so-called magnetodendrimers could be followed by MRI. But to advance to clinical trials, the researc...

Anti-cancer drugs may hold promise for premature aging disorder

...mprovements in the animals' conditions, a clinical trial of FTIs in children with progeria may begin as early as next spring, researchers said. Dr. Collins and his colleagues discovered in April 2003 that mutations in the lamin A (LMNA) gene cause progeria, spurring renewed interest among researchers to ...

NIAID researchers show how promising TB drug works

...tent TB. (For information about the first clinical trial of PA-824, see June 14, 2005, NIAID press release: http://www3.niaid.nih.gov/news/newsreleases/2005/tb_pa_824.htm .) PA-824 must be chemically activated in the bacterium before it exerts its anti-tubercular effect, notes Dr. Barry. Earlier research...

Cyberkinetics, Case to develop system to help restore extremity function

... the only group to obtain FDA-approval for a pilot trial in humans using an implantable multichannel, intra... BrainGate TM System. In its first pilot clinical trial currently underway, clinical researchers are testing the safety and feasibility of the BrainGate in ...

Careless reporting on HIV 'could cost lives'

...ister halts AIDS drug trial, and Cameroon suspends trial of AIDS drug after protests). Mills and colleague...rrect". Some reports said opposition grew because trial participants were not offered adequate medical insurance, others said it was because those taking pa...

Zinc supplements safe for HIV-infected children

...eted a randomized, double-bind, placebo-controlled trial of zinc supplementation at an urban hospital in Pietermaritzburg, South Africa. The 96 children in the study were cared for on a monthly outpatient basis by a team of medical doctors and nurses. Parents were taught how and when to give the 10-mg zinc...

PLoS Medicine publishes first trial of effect of male circumcision on HIV infection

The peer-reviewed results of the first trial of the effect of male circumcision on HIV infectio...be published in PLoS Medicine on October 25. The trial found that circumcision reduced the rate of new infections among heterosexual men in South Africa by...

UK is first to administer new anti-clotting technology

...e is one of two sites participating in the Phase 1 trial and is the first site to use the anti-clotting drug and its antidote. This clinical trial will examine the drug's safety and tolerability in healthy volunteers as well as the antidote's abil...

Hand sanitizer gel works

Randomized trial finds reduced spread of GI infections in families ...d of GI illnesses. "This is the first randomized trial to show that hand sanitizer reduces the spread of germs in the home," says Dr. Thomas J. Sandora, a ...

Minimally Invasive Cancer Treatments Highlighted

...Studies of note: ?Interim results of a cryoplasty trial show the treatment provides effective and durable ...gligible mortality. Study of note: ?A prospective trial in 106 patients receiving RFA to heat and kill their lung tumor, shows 91% cancer-specific survival ...

Researchers use brain scans to predict behavior

...which subjects variably directed attention on each trial to the location of the stimulus prior to its presentation," says Maurizio Corbetta, M.D., the Norman J. Stupp Professor of Neurology and senior author of the study. Regardless of how the results are interpreted, Corbetta notes, the study clearly show...

Bone marrow stem cells may heal hearts even years after heart attacks

...ate on a larger, prospective randomized controlled trial in order to strengthen the statistical power of th...resting. However, let's do a double-blind clinical trial and then we'll know for sure where we stand at this stage." Dr. Anversa said the field of cardiac r...

A New Era Of Hope For Neglected Diseases

...s). Thirteen of them have already reached clinical trial stage and two are awaiting regulatory approval (rectal artesunate for malaria, and paromomycin for visceral leishmaniasis). These PPP-driven projects should result in six or seven new drug registrations in the next five years. Research by Dr Moran a...

Updated data on novel HPV vaccine confirms efficacy in large population

... and the most common adverse event reported in the trial was local discomfort at the injection site. The study is part of an ongoing phase III program involving more than 25,000 people in 33 countries. For the FUTURE II study, a prospective, randomized, double-blind, placebo-controlled study, women aged...

Survey Uncovers Surprising Attitudes Towards HIV Vaccine Research

...e U.S. government’s ability to protect HIV vaccine trial volunteers. While about half of three groups ?men ... could trust the government to protect HIV vaccine trial volunteers, the rate of trust among Hispanics was significantly higher at 78 percent. Based on inte...

Experimental shingles vaccine proves effective in nationwide study

...hingles occur in the United States each year. The trial was conducted at 22 study sites nationwide, including 16 VA medical centers and six clinical research sites outside the VA system coordinated through NIAID. Between November 1998 and September 2001, the multicenter research team enrolled more than 38...

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