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Tag: "trial" at biology news

Compound might defeat African sleeping sickness, clinical trial beginning this month

...ing sickness. Scientists are launching a Phase III trial this summer involving for the first time hundreds ... she and colleagues started the Phase III clinical trial this month. The new pivotal trial will involve approximately 250 patients in the Democratic Republic...

Scientists turn tobacco against cancer

...wski notes, would be to conduct a phase 1 clinical trial of the monoclonal antibody in colorectal cancer patients. In the meantime, they are studying the effectiveness of monoclonal antibodies against other types of cancer, including breast tumor and lung tumor cells, in laboratory animals. ...

Study shows humans have ability to track odors, much like bloodhounds

... tell you how accurate he or she would be on every trial and on the task overall," Sobel said. "So the fact that we have this predictive value in the data really suggests that we have actually successfully captured the mechanism." What's more, another area of the brain outside the olfactory cortex was ver...

Study Finds Moderate Hypothermia A Safe Treatment For Traumatic Brain Injury In Kids

A first-of-its-kind multi-center trial has shown that cooling the body can have positive ...The trial, which is the only multi-center clinical trial involving children underway in the United States, was conducted to determine whether moderate hypoth...

Morphine for Chest Pain Increases Death Risk

...g. The researchers call for a randomized clinical trial to confirm their analysis. Meanwhile, they advise ...e use found in our analysis, a randomized clinical trial is in order." Morphine was first used to relieve the chest pain associated with heart attacks in 19...

Stem cell therapy successfully treats heart attack in animals

...Institute, and senior author of the study and lead trial investigator. "There is reason for optimism about these findings, possibly leading to a first-ever cure for heart attack in humans," he says. "If a treatment can be found for the damage done by a heart attack to heart muscle, then there is the poten...

Moffitt-USF head toward first human trials of anti-cancer drug that targets protein AKT

...headlines and at medical conferences. The clinical trial of this Akt-inhibitor is a concrete step toward that reality. Sebti says, "The beauty of this trial is that it's molecular therapy, based on the blueprint of the tumor cell." ...

Does vitamin C help prevent or treat the common cold? Maybe not, after all.

...3) The authors say that the results in this single trial are "tantalising and deserve further assessment." Douglas and Hemilä's article summarizes their more detailed review of the evidence that is published by the Cochrane Library (see www.cochrane.org) and that is freely available via the PLoS Medicine ...

Researchers test new therapy for advanced melanoma

...st melanoma tumors. "This is a milestone clinical trial because it is the first time that electroporation ...ller and his colleagues preceded the initial human trial begun earlier this year at Moffitt. The collaboration of USF and Moffitt in this trial is a good exa...

'EuroVacc 02' HIV Vaccine Trial Begins

...t HIV/AIDS today announced that a phase I clinical trial of novel investigational vaccines comprising DNA-H...s, HIV-negative and at low risk of infection. The trial will carefully evaluate the safety and immunogenicity of the combination of the vaccines, in particu...

Single-donor Islet Transplantation Procedure Shows Promise For Patients With Type 1 Diabetes

... islet transplantation from a single pancreas. The trial was conducted from July 2001 to August 2003 and en...lled eight women with type 1 diabetes. During the trial there were no serious, unexpected, or procedure- or immunosuppression-related adverse events. All ei...

Prescription Drug Patches Gaining Ground, Tackling New Therapies

...ind their way through the development and clinical trial process. Growth in demand for prescription drug patches is being driven by several factors ?factors with strong demographic and population trend underpinnings. Technology has also played a major role in prescription patch growth. Advances in synthet...

Ariadne Genomics Announces the Release of PathwayStudio?Central, Client-Server Software for Biological Pathway Analysis

...thwayStudio?Central is available for a free 20 day trial at www.ariadnegenomics.com. PathwayStudio?Central builds pathways from microarray data, identifies biomarkers, and models drug responses. The software comes with ResNet?database of 500,000+ functional relationships and MedScan?tool for automatic ext...

Supercomputers to focus brains on AIDS dilemma

...clinical trials this year, with UCSD as one of the trial sites. The Merck scientists have chosen a drug development strategy in which they are developing "single wing" compounds, whose wings, or cyclic moieties, can bind to either the west or the east in the integrase enzyme. "These compounds are especial...

Bevacizumab Combined With Chemotherapy Improves Progression-Free Survival for Patients With Advanced Breast Cancer

...liminary results from a large, randomized clinical trial for patients with previously untreated recurrent o...me chemotherapy without bevacizumab. The clinical trial was sponsored by the National Cancer Institute (NCI), part of the National Institutes of Health, and...

Measuring Enzymes At End Of Cancer Pathway Predicts Outcome Of Tarceva, Taxol

...several hours," Ueno says. He adds that a clinical trial is currently under way that tests CDK activity both before and after patients with breast cancer are treated with Taxol. ...

OneWorld Health drug receives 'Orphan' designation from U.S. and European regulatory agencies

...nal parasites. The largest-ever Phase III clinical trial for visceral leishmaniasis was completed in Novemb... World Health Organization (WHO/TDR). The clinical trial used the injectable form of paromomycin in 667 patients in India. ...

NIAID begins clinical trial of West Nile virus vaccine

A small trial testing the safety of an experimental vaccine targeting West Nile virus (WNV) opened today at the National Institutes of Health's (NIH) Clinical Center in Bethesda, MD. The vaccine, which will be tested first in 15 healthy adult volunteers, was devel...

Roche clinical trial registry and results database launched

...nic database, Roche is launching a public clinical trial registry and results database using an independent...publicly accessible protocol registry and clinical trial results database today. Transparency has always been and continues to be a priority for us. In Janua...

Technique may allow cancer patients to freeze eggs, preserving fertility before starting treatment

...ve baby with her own eggs," Smith says. A clinical trial through the U-M Comprehensive Cancer Center is planned to begin by fall. ...

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