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Tag: "trial" at biology news

Enzyme delivered in smaller package protects cells from radiation damage

...ation, and in preparation for a potential clinical trial of systemic MnSOD in humans, the University of Pit...roup is currently conducting a phase I/II clinical trial in lung cancer patients consisting of twice-weekly swallowed MnSOD for protection of the esophagus f...

Liver cancer patients with high serum levels of hepatitis B virus face poorer outcomes

...participating in a phase III randomized controlled trial comparing two different chemotherapy regimens. One hundred and seventy patients (92 percent) had evidence of HBV infection. Of these, 125 had sera available to determine HBV DNA levels and were included in the study. For each patient, the researc...

Snoring in children might be an allergic type disease

... Prevention Study (CAPS) – a randomised controlled trial of dietary intervention and house dust mite avoidance during the first five years of life. 219 children within the original study group had rhinitis and of these, 213 could provide information on snoring. Almost 60% of these children snored at le...

Newly discovered antibody may be body's natural defense against Alzheimer's

...ls in Alzheimer's patients in our Phase I clinical trial were much more profound than we expected," Dr. Relkin explains. "We couldn't readily explain this based on the low levels of anti-amyloid antibodies known to be present in IVIG. We suspected there might be another, unseen player." His laboratory ...

Gene therapy study shows safety and statistically significant improvement in Parkinson's disease

... positive results from the first ever gene therapy trial for Parkinson’s disease and the first report of di... “We are very encouraged by the results of this trial and its publication in such a prestigious journal,” said John Mordock, Neurologix President and Chie...

Focused ultrasound relieves fibroid symptoms in women

...according to the results of a multicenter clinical trial reported in the June issue of the journal Radiology. Magnetic resonance-guided, focused ultrasound surgery (MRgFUS) allows radiologists to precisely target fibroids without harming healthy surrounding tissue. "This treatment immediately stops blood...

How brain pacemakers erase diseased messages

...ice," he said. "Therefore, it might take months of trial and error to find the optimal setting." Grill's new model promises to streamline the process. ...

Resistant HIV quickly hides in infants' cells

... of age enrolled in a large, multi-center clinical trial covering 10 states. Their results showed that five of 21 HIV-positive infants were infected with drug-resistant HIV transmitted from their mothers—a surprisingly high figure. Of those five, four were resistant to non-nucleoside reverse transcript...

A cherry on top: Tart cherries may alter heart/diabetes factors

... but a U-M team will soon launch a small clinical trial to start to find out. Meanwhile, additional resear...the U-M Medical School, will lead a pilot clinical trial of whole tart cherries in humans. The study will enroll healthy individuals who will spend a night a...

US control strategies may make flu epidemics worse, UCLA study shows

...ly vaccination decisions as an adaptive process of trial and error. They tracked both individual-level decisions and population-level variables ?that is, the yearly vaccine coverage level and influenza prevalence, where prevalence is defined as the proportion of the population that is infected. The individ...

Maggots rid patients of MRSA

...y Diabetes UK to carry out a randomized controlled trial to compare this treatment with two others. "Maggots are the world's smallest surgeons. In fact they are better than surgeons - they are much cheaper and work 24 hours a day," Professor Boulton jokingly said. "They have been used since the Napol...

First clinical trial of gene therapy for childhood blindness

The first clinical trial to test a revolutionary treatment for blindness in...mpact on future treatments for eye disease. The trial involves adults and children who have a condition called Leber’s congenital amaurosis (LCA), which i...

Warts vaccine -- 1 of many in pipeline

A clinical trial treating the papillomaviruses responsible for geni...stralian of the Year 2006 Professor Ian Frazer and trial manager, sexual health specialist Dr David Jardine More than 200 patients in China and Australia h...

Dealing deadly cancers a knockout punch

..., Oncolytics announced it had initiated a Phase II trial to evaluate intravenous administration of Reolysin...ed to begin in 2007, including a Phase II melanoma trial and a Phase I/II ovarian cancer trial. "It is hoped that the trials will clearly show that Reolys...

No magic tomato? Study breaks link between lycopene and prostate cancer prevention

..., an ongoing, randomized National Cancer Institute trial to evaluate cancer screening methods and to invest...rrence of prostate cancer, death or the end of the trial in 2001. At the beginning of the trial, the men gave a blood sample and completed a questionnaire re...

Investigating the measles virus as a tool to kill multiple myeloma

...ic Cancer Center has opened a new Phase I clinical trial testing an engineered measles virus against multip...d lead researcher on the multiple myeloma clinical trial in the measles virus investigation. “We are very hopeful that this will be a step toward helping our...

Biodiesel study targets cleaner air, cleaner engines

...a monitored exhaust emissions from tractors at the trial sites, including levels of carbon dioxide, nitrogen oxides and particulate matter. Although commercially available, biodiesel has never been tested on agricultural machinery in Canada and has not yet been widely used by farmers. It is hoped the r...

30+ AIDS vaccine clinical trials in 24 countries, research occurring on every continent

...comprehensive listing of all AIDS vaccine clinical trial activity worldwide. Last year saw the start of ...e United States. In 2006, IAVI launched a Phase II trial in Uganda and Zambia, part of a multi-site study that also included three sites in South Africa. The...

NIAID DNA vaccine for H5N1 avian influenza enters human trial

The first human trial of a DNA vaccine designed to prevent H5N1 avian in...za and other diseases." "This influenza vaccine trial is further evidence of the ability of the NIAID Vaccine Research Center to rapidly translate basic r...

Africa's first large-scale HIV vaccine study launches

...orators in the United States and South Africa. The trial will involve up to 3,000 participants at five site...Diseases of the National Institutes of Health. The trial sites also receive funding from the South African AIDS Vaccine Initiative. "This trial will answer...

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