Study examines risk of soft tissue sarcomas in hereditary retinoblastoma survivors
...gs may be applicable only to patients who received treatments that are no longer used. "Improved treatment can be expected to reduce the incidence of soft tissue (and bone) sarcomas associated with radiation," Meadows writes. "The importance of this [new] report lies in its emphasis on leiomyosarcoma, a tumor t...NT researchers discover breakthrough in malaria treatment
... Papua, where they compared, head to head, two new treatments for malaria. Both contained a combination of drug...imalarial drug. The researchers found that both treatments provided initial cure from disease. However those receiving a treatment which stayed in the blood s...Breakthrough vaccine to treat chemo-resistant ovarian cancer
...tal we do everything we can to make innovative new treatments like this available to patients as soon as possible," said Dr. Staren. It's inconceivable that treatments like these ?that give hope to patients ?are often left on the laboratory bench, while cancer patient...A genetic 'gang of 4' drives spread of breast cancer
...ombination are being discussed, "there are already treatments to diminish the chance of metastasis in breast cancer, so such trials would have to be designed very carefully to understand how and whether the new drug combination would be of additional benefit." In the article published in the Proceedings of the ...New study challenges 'critical period' in childhood vision development
... provide an argument for even late-stage blindness treatments and guide researchers towards an improved understanding of the complexities of the brain. ...Genetic pathways to curable and incurable forms of pancreatic cancer identified
...developing early detection biomarkers and possible treatments to halt the progression of the disease. The work involved activating the pancreatic cancer oncogene called Kras and then selectively mutating tumor-suppressor genes such as p53, p16 and Dpc4 in different combinations. In the mouse model, which Hi...Scientists hoping to find new treatments for one of the world’s most deadly infectious diseases say drugs used to treat common fungal infections may provide the answer. Tuberculosis, or TB, is a highly contagious disease of the lungs that was thought to have been virtually eliminated by th...Early-stage sperm cells created from human bone marrow
...t has potential applications in terms of fertility treatments in humans. Prof Nayernia gained worldwide acclaim in July 2006 when he announced in the journal Developmental Cell that he and colleagues had created sperm cells from mouse embryonic stem cells and used these to fertilise mice eggs, resulting in ...Yale biologists 'trick' viruses into extinction
... "This approach has intriguing potential for new treatments against human viruses," said Turner. "A similar idea already exists in agriculture, where farmers use non-harvested 'trap crops' to lure insect pests. Because the pests prefer the taste of the trap crops, only these plants need to be sprayed, reduci...Scientists find new genes for Crohn's disease
...cts to unravel the causes of, and hopefully better treatments for complex, enigmatic diseases". In addition to finding the additional Crohn's disease susceptibility genes, the researchers got strong signals for genetic risk factors located in areas of the genome where there are no known genes. "Further work ...Elucidation of the genome for diabetics with DNA chips
...porter gene in particular, may be good targets for treatments to combat DT2. These results from the analysis of very high-density DNA chips ?the first in the world for a common disease like DT2 ?demonstrate the validity of this approach. The method will be made available in France in March 2007, through the ...Protein discovery targets antibiotic-resistant bacteria
...University researchers may be useful in developing treatments for antibiotic-resistant bacteria, such as those that cause food poisoning and typhoid. By solving the structure and activity of the protein ?called YihE or RdoA ?a team of professors and students from the departments of Biochemistry and Microbiolo...UCSF brain tumor vaccine trial shows promising results
...fects typically associated with traditional cancer treatments such as chemotherapy and radiation therapy. Vitespen has been granted fast-track and orphan drug designations from the Food and Drug Administration for both metastatic melanoma (skin cancer) and renal cell carcinoma (kidney cancer). Reviewing the...Scripps research team discovers a chemical pathway that causes mice to overeat and gain weight
...e. The most common anti-inflammatory and analgesic treatments like ibuprofen are aimed at reducing PGE2 signalin...eding and obesity could lead to the development of treatments that could prevent or reverse these conditions. Along with Sanchez-Alavez and Bartfai, Izabella ...Study identifies risk factors for spread of respiratory infections in hospitals
...spread of SARS. The authors hypothesize that these treatments may propel infectious air from these patients farther than without masks or ventilation. Alternatively, they may generate more infectious aerosols. "There is a gap in the knowledge of how oxygen and ventilation therapy may promote the spread of i...Exploring the molecular origin of blood clot flexibility
...useful for developing prophylactic and therapeutic treatments for many aspects of cardiovascular disease and stroke, suggest the investigators. ...Genes and biomarkers that allow doctors to choose the right therapy for the right patient
...040. Their findings could help in individualizing treatments for women, and their methodologies could aid in identifying similar biomarkers for responses to other drugs and for other types of cancer. "Individuals respond differently to different therapeutics because there are substantial differences in the ...Prenatal cocaine's lasting cellular effects
...peractivity disorder (ADHD). However, the standard treatments for ADHD -- Ritalin and other stimulants -- are not always effective in these children. Studying the effects of prenatal cocaine exposure on the developing brain is difficult in human populations because cocaine abusers often abuse other drugs. A...FSU researchers determine a critical factor in workings of proteins
... of how proteins bond could lead to more effective treatments for genetic disorders and other life-threatening conditions. Now, a pair of Florida State University researchers' new theory has been proven to accurately predict the association rate for proteins. Their theory is outlined in the February issue of t...... explains. "There is currently a lack of effective treatments and our proposed drug is based on a natural way of controlling the body's appetite, which makes it more attractive." ...