Automatic identification of protein's critical features from the structure
...nd how living forms work, and to develop effective treatments and diagnostic tests. The scientists led by Dr. Gabriel del Río at the Instituto de Fisiologia Celular/UNAM, developed an automatic procedure that allows scientists for the first time to identify the critical elements of proteins from their shape...Effect on breast tumors of DNA alternations in 3 genes described
... for the hormone estrogen. Such tumors respond to treatments that block these receptors. "Similarly, hypermethylation of E-cadherin was more frequent among progestin receptor (PR)-negative cases," said Tao. "Compared to tumors that were both ER- and PR-positive, tumors that were both ER- and PR-negative w...First demonstration of new hair follicle generation in an animal model
... understanding of this process could lead to novel treatments for hair loss, other skin and hair disorders, and wounds. “We showed that wound healing triggered an embryonic state in the skin which made it receptive to receiving instructions from wnt proteins,?says senior author George Cotsarelis, MD, Associ...Cow protein aids in treatment of gastrointestinal disorder
...al therapy plus lactoferrin than with the existing treatments and may be used without risk of resistance. “Various studies are under way to evaluate new antibiotics and different therapeutic methods to increase the efficacy of H. pylori therapy,?says lead author Nicola de Bortoli, M.D., Ph.D., adding that “d...NIDA study identifies genes that might help some people abstain from smoking
...y be able to make use of this information to match treatments with the smokers most likely to benefit from them.? ...Bones in motion: Brown scientists to create new 3-D X-ray system
...igh-speed imaging system will contribute to better treatments for knee, shoulder, wrist and back injuries and he...ess of different approaches; creating better treatments for shoulder, wrist, knee and back injuries; driving innovations in computer graphics and scie...Study examines genetic risk factors for Alzheimer's disease
...nowledge base for the development of potential new treatments and diagnostic tests. This study is just the first in series we are undertaking using new technology to look comprehensively at every gene in the human genome in Alzheimer’s Disease and we hope that there are other exciting findings to come.? Ther...Genetic fingerprints identify brain tumors' origins
...ation about tumor origins to develop new tests and treatments for the tumors. Brain tumors are the leading cause of cancer-related death in children, and the most common childhood brain tumor is the pilocytic astrocytoma (PA). Approximately 15 percent of all PAs are linked to neurofibromatosis 1 (NF1), a geneti...Scientists identify pancreatic cancer stem cells
...that, based on some preliminary research, standard treatments like chemotherapy and radiation may not be touching these cells," said Simeone. "If that is why pancreatic cancer is so hard to treat, a new approach might be to design a drug that specifically targets pancreatic cancer stem cells without interfering...Stanford-led study closes in on genes that may predispose some people to severe depression
...ore effective therapies to treat depression. "The treatments we have now are lifesavers for some people, but there are others who have only a partial response or no response at all," he said. "Understanding the biology would help the search for better treatments." The next phase of the consortium's rese...NIH researchers discover protein that appears to regulate bone mass loss, the cause of osteoporosis
... researchers, is to determine whether experimental treatments designed to correct the immune deficiency of X-linked Hyper IgM Syndrome can also reverse the bone loss. If so, the knowledge gained from these studies may benefit people at risk of developing osteoporosis. ...A 'traffic light' for neurons means 'go' for improving brain research
... development of targeted genetic or pharmaceutical treatments to fix those neurons. Conceivably, direct control of neuronal activity with light could someday become a therapy in itself. A neural traffic light To selectively take control of neurons, the researchers used a virus to insert genes for produc...Researchers from the University of Navarra analyze new kinds of cancer-fighting antibodies
...er, and is capable of interacting with the current treatments so as to make both forms of treatment more powerful. Currently this treatment is being tested in patients with melanoma, kidney and ovarian cancer because there are more ways of measuring the response of the immune system, but he expects to be ab...Study shows isolation of stem cells may lead to a treatment for hearing loss
...lian cochlea. Currently there are no clinical treatments to repair these hair cells vital to normal hearing. In the United States, 30% of people over the age of 65 have a handicapping hearing loss and of those, one in 500 people become deaf before reaching adulthood. In most cases, the target is the high...Power-boosting signal in muscle declines with age
... enzyme and, in turn, mitochondria production. The treatments included acute exposure to an AMPK-stimulating chemical, chronic exposure through feeding of another chemical that induces AMPK by mimicking an energy shortage, and exercise. In every case, older rats showed a decline in AMPK activity compared to...Better assessment of transfusions could save blood
...globin levels. New research shows that alternative treatments may lead to fewer transfusions, conserving critical blood supplies in hospitals. The report is published in Seminars in Dialysis. Phlebotomy, the removing of blood from the body, has been seen as a major factor contributing to anemia, but recent re...OHSU surgeon implants donated tissue allografts
... in several trials to assess the efficacy of these treatments and continue to pioneer cartilage surgery treatments. ...Study calculates patient time costs associated with cancer care
...te. Nevertheless, Kessler and Ramsey conclude, new treatments that reduce patient time costs should be encouraged, and manufacturers should quantify these benefits and then convey them to patients, providers, and health insurers. ...'Marathon mice' elucidate little-known muscle type
... composition of muscle, the researchers said. Such treatments might have the potential to boost physical strength and endurance in patients with a variety of muscle wasting conditions. The research team, led by Bruce Spiegelman of Harvard Medical School, found that increasing activity of the gene known as PG...Discovery could lead to better control of hemorrhagic fever viruses
... Choe now hopes to translate these findings into treatments to contain natural or intentional outbreaks of New World hemorrhagic fever. Serendipitously, several anti-TfR1 antibodies have already been developed as anticancer therapeutics (cancer cells are also high in TfR1), and some have already been through ...