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Tag: "treatment" at biology news

Leukemia Drug Breakthrough Study In New England Journal Of Medicine

...veloped the phase I clinical trial of Revlimid for treatment of MDS following his laboratory observations that the agent improved the growth of red blood cell precursors from MDS bone marrow. Celgene will submit the seminal findings of List's phase I trial - along with data from two recent confirmatory phase I...

Gene therapy converts dead bone graft to new, living tissue

... aid people with various cancers or injuries whose treatment involves the replacement of large sections of bone. Cancers such as osteosarcoma, one of the most common types of bone cancers, or tumors that occur adjacent to bones, often must be treated by removing the diseased section of bone and replacing it wi...

Novel Therapy Tested in Mice Could Chase Away Cat Allergies

...ID Director Anthony S. Fauci, M.D. The injectable treatment puts a brake on the release of a key chemical from...ldren 6 to 19 years old are allergic to cats. The treatment comprises a molecule that loosely tethers a feline and a human protein together. The feline end is t...

Mouse brain tumors mimic those in human genetic disorder

...a childwith an optic pathway glioma should undergo treatment for the tumor,including the tumor's size and the patient's clinical symptoms. Butoften those tests aren't sufficiently informative, so experts alsoexamine pictures of the patient's brain taken with magnetic resonanceimaging (MRI). To capture such bra...

Enzyme allows B cells to resist death, leading to leukemia

...restorethe process of cell apoptosis to normal and treatment of malignantcells with drugs that induce cell death decreased both Lyn expressionlevels and activity ?suggesting a direct correlation between high Lynactivity and the ability of these B cells to resist apoptosis. Theauthors suggest that Lyn is involv...

New imaging method gives early indication if brain cancer therapy is effective, U-M study shows

...tential to spare patients from weeks of a grueling treatment regimen that's not working and gives doctors the o...ith 100 percent accuracy after only three weeks of treatment whether the therapy would be effective ?10 weeks before traditional methods would show a response. ...

Gene variations explain drug dose required to control seizures

... emerge from a partnership, aimed at tailoring the treatment of epilepsy to patients' genetic makeup, between t...atients in drug response, allowing better informed treatment decisions," he continued. Control of epilepsy with phenytoin can be a difficult and lengthy process...

Solution to Pollution: New Bacteria Eats Toxic Waste

...kamsk in the Russian Federation to assist with the treatment of industrial residues, in Poland to renew soils for agricultural production and in the Netherlands to clean up sediments dredged from canals and waterways. “I want to congratulate the Utah State team on the funding for this project,?said Joop Harmse...

Muscle-targeted gene therapy reverses rare muscular dystrophy in mice

...uke University Medical Center to find an effective treatment for Pompe disease. The Duke team earlier developed...ed virus. Gene therapy might offer an alternative treatment for those children who fail to respond to enzyme replacement therapy, he said. Even for those that r...

Purdue proves concept of using nano-materials for drug discovery

...ve chemotherapy drugs from tumor cells, making the treatment less effective. Cancer cells exposed to chemotherapy drugs produce a disproportionately large number of the pumps, causing the cells to become progressively more resistant to anticancer drugs. Engineers and scientists in the Purdue center are trying...

U-M scientists find genes that control growth of common skin cancer

... The new finding has important implications forthe treatment of this widespread disease.Their report will be published in the Jan. 15 issue of Genes &Development, but is available now on the journal's Web site . Basal cell carcinoma (BCC) affects over 1,000,000 Americans each year and frequently develop...

Taking Aim With Nanoparticle PEBBLEs

...f brain cancer called 9L-gliosarcoma, PEBBLE-based treatment significantly increased survival time. People who get that type of cancer usually live less than four months without treatment; rats die within about five days. When Kopelman's group treated rats with PEBBLEs that weren't even tailored to home in on ...

Genetically modified natural killer immune cells attack, kill leukemia cells

...way to improve the outcome of children who receive treatment for acute lymphoblastic leukemia (ALL) or other bl...Blood report. Progress in adapting NK cells to the treatment of ALL had been significantly hampered because researchers were not able to grow large numbers of th...

Scientists identify genetic pathways essential to RNA interference

...titis C or cancer-causing oncogenes. An RNAi-based treatment for age-related macular degeneration is already in clinical trials." Ruvkun is a professor of Genetics at Harvard Medical School. RNAi was originally identified in the C. elegans roundworm and the flowering plant Arabidopsis thaliana, both of which ...

Gene Therapy For Parkinson's Disease Moves Forward In Animals

...lity of life. It would be a huge change in the way treatment is done,?said Mandel, a neuroscientist in UF's Col...s Björklund of Lund, a pioneer of the experimental treatment involving the transplantation of fetal cells into the brains of Parkinson's patients, and his collea...

Development of portable infectious disease detector

...s for clinicaldiagnosis and biodefense.""Today the treatment for AIDS is very expensive and there is always aquestion about when to start and stop anti-retroviral therapy," saysPria's Chief Technology Officer Jason Pyle. "We are developing a devicethat we hope will allow medical professionals and HIV patients ...

Researchers add new tool to tumor-treatment arsenal

... a drug combination could dramatically improve the treatment of solid tumors." ...

Alcohol's effects on gene expression in the central nervous system

...use, and could aid in the development of selective treatment strategies for different subgroups of alcoholics." McBride added that, despite recent advances, researchers need further developments in microarray technologies and bioinformatic approaches to better understand the complex neurobiological mechanisms...

Potential Cure for Lymphoma in HIV patients

...this disease and HIV. A new study showingthat this treatment is a viable option for select patients withHIV-ass...lop lymphoma than HIV-negativeindividuals, and the treatment for their cancer is far less likely tobe successful. SonaliSmith, M.D., Assistant Professor of Medi...

Deficiency of growth hormone and IGF-1 reduces cancer and kidney disease, but creates other problems

...and 14 weeks of age ?rat adolescence. Then hormone treatment was stopped and the animals had lower growth hormone and IGF-1 levels the rest of their lives. That had an effect on cancer: 88 percent of "normal" male rats have tumors at death. The male rats that had a lifelong deficiency of growth hormone had su...

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