Long-term cancer risk follows stem cell transplant recipients
...ively reviewed the medical records of 926 patients treated with myeloablative stem cell transplants over an 18-year period. They found that at their institution the 10-year incidence of second cancers in these patients was 3.1 percent. When nonmelanoma skin cancer and carcinoma in situ of the cervix were ...Insulin receptor stops progression of Alzheimer's disease
...isease, providing evidence that the disease can be treated in its early stages, according to a study by researchers at Rhode Island Hospital and Brown Medical School. Researchers have found that peroxisome-proliferator activated receptor (PPAR) agonists prevent several components of neurodegeneration and p...Chemotherapy temporarily affects the structures of the human brain
...subjects. They found that at one-year, patients treated with chemotherapy had smaller volumes in cognitively sensitive areas, such as the prefrontal, parahippocampal and cingulate gyri, and precuneus regions. However, at three-years post-surgery there was no volume differences. That there were no differen...Other patients bear the real cost of Herceptin
... hyperbole should not be the determinant of who is treated and with what, they argue. In NICE we have an established system, but it is currently creating more problems than solutions. They believe that NICE should be given responsibility to decide what should be cut to fund newly recommended technologies...Computer-based 'games' enhance mental function in patients with Alzheimer's
...diagnosed with Alzheimer's disease. All were being treated with cholinesterase inhibitors, the most common pharmacological treatment for Alzheimer's, for at least one year prior to enrolling in the study; all participants remained on the drug for the duration of the study. Participants were randomized to ...Better sludge through metagenomics
...ng--more than 31 billion gallons of wastewater are treated daily in the U.S. alone. Even a marginal improvement in the process would translate into huge savings and spell relief for environmental engineers. David Jenkins is Professor Emeritus of Environmental Engineering at the University of California at...Minorities, uninsured less likely to receive care at high-volume hospitals
...s, while uninsured patients were less likely to be treated at high-volume hospitals for 9. " ?our study demonstrates robust findings in a large (12 percent of the U.S. population), ethnically diverse population that includes all patients undergoing the selected procedures without restrictions based on demo...Resistant bacteria increasing source of muscle infection
...nt of community-acquired staphylococcal infections treated at Texas Children's Hospital are MRSA (resistant to the antibiotics commonly used to treat these infections in the past), she said. The rate of such infections is increasing nationwide. In surveying patient records, Pannaraj and her colleagues fou...A new jump start for aging blood vessels
...irst study of its kind. Csiszar and collegues treated aged rats with etanercept to test the hypothesis that anti-TNFa treatment exerts vasculoprotective effects in aging. Etanercept (Enbrel) is an FDA-approved drug that binds and inactivates circulating TNFa. Recent studies have demonstrated that anti...Cell wall of pneumonia bacteria can cause brain and heart damage
...ted for 16 hours with CV-6209 survived, while mice treated after inoculation of cell wall did not. "Our success in preserving cardiomyocyte function even in the presence of cell wall suggests that it might be possible to safely pre-treat people infected with S. pneumoniae with a drug that blocks PAF befor...Bacterial protein shows promise in treating intestinal parasites
...n the first day," said Aroian. "Laboratory animals treated with Cry5B survived a lethal hookworm infection, and showed no side effects from the medication." Colleagues in Cappello's lab then carried out additional experiments that demonstrated that Cry5B was comparable to mebendazole for treating hookworm ...Three-in-one virus killer prevents common, often fatal infections
...vered completely within two to four weeks of being treated without any side effects or toxicity. Preexisting therapies for adenovirus have had little success ?there is an 80 percent chance of death following the development of adenovirus. "Not only were patients prevented from getting these infections aft...Study of gene transfer for erectile dysfunction shows promise
...hat a larger study that includes a "control" group treated with a placebo is needed to confirm the safety and effectiveness of the treatment. Other researchers on the project were Melman, Natan Bar-Chama, M.D., with Mount Sinai School of Medicine, Andrew McCullough, M.D., with New York University School ...Targeted virus compels cancer cells to eat themselves
...ng mice with malignant gliomas in the brain, those treated with three injections of hTERT-Ad on average lived 53 days. Those receiving the control adenoviruses lived on average 29 days. Two of the hTERT-Ad mice survived 60 days and had no detectable brain tumors. Analyses of dead cancer cells showed tellta...Inheriting a tendency to brain infection
... care unit with herpes simplex encephalitis may be treated with both the standard antiviral, acyclovir, and w... another interferon pathway have been successfully treated with the interferon they lack. Based on the results in patients with TB, Casanova hopes the combined...UWM brain research supports drug development from jellyfish protein
...e "lab" equivalent of a stroke, and more than half treated with aequorin survived without residual toxicity. Why does it work? Diseases like Alzheimer's are associated with a loss of "calcium-binding" proteins that protect nerve cells, said Moyer. Calcium is necessary for communication between neurons in ...Scientists use gene signatures to match cancer and other diseases with potentially effective drugs
...mpare them with signatures of cells that have been treated with a large number of drugs, both old and new. Th...es the signature of a reference cell that has been treated by a particular drug, the greater the odds that the drug will be an effective treatment for that dis...Tastes great! Study shows brain's response to pleasing -- and changing -- tastes
...nd, they repeated the tests when the rats had been treated with drugs that greatly reduced their bodies' salt levels. At first, the rats all behaved negatively after tasting a strong salt-water solution, compared to the water or sugar water. Their ventral pallidum brain activity was also much lower in res...MRSA vaccine shows promise in mouse study
...nt source of skin infections, which can usually be treated without antibiotics, but it can also cause serious surgical wound infections, bloodstream and bone infections, or pneumonia. The burden of such infections, according to one recent study, is "staggering: almost 12,000 inpatient deaths annually," an e...Results with newer bladeless LASIK equivalent to standard microkeratome LASIK
...r nearsightedness or astigmatism. Each patient was treated with microkeratome LASIK in one eye and bladeless ...ce in vision after three months between their eyes treated with bladeless or microkeratome LASIK. Backscatter is haziness in the cornea that is usually invisib...