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Tag: "treated" at biology news

Elucidation of the genome for diabetics with DNA chips

...nfirmed in more than 5500 French diabetic patients treated at Corbeil-Essonnes Hospital (Guillaume Charpentier) and Poitiers University Hospital (Samy Hadjadj) and in additional control subjects. These results demonstrate very strong associations between DT2 and at least four genes encoding proteins playing ...

Protein discovery targets antibiotic-resistant bacteria

...,?says Dr. Martin. In North America, the people treated for food poisoning with drugs tend to be elderly or “immune compromised?where there is a need for antibiotics to clear the infection. Since the organism that causes salmonellosis is related to that responsible for typhoid fever ?a huge problem in les...

Researchers urge monitoring of bone health during chemotherapy

...e that did not receive G-CSF. Interestingly, mice treated with a bisphosphonate, an anti-osteoporosis agent that inhibits osteoclasts, were resistant to the effects of G-CSF on bone tumor growth. Weilbaecher is currently investigating bisphosphonates as a means to prevent tumor metastasis to bone in breast ...

Finnish scientists discovered a new approach to treat virus-induced lymphomas

...sulted in a marked regression of all tumors in the treated animals in two weeks. These results demonstrate that p53 reactivation via Nutlin-3a is an efficient treatment for KSHV-lymphomas in mice and suggest a novel therapeutic strategy for treatment of these fatal virus-induced malignancies also in humans....

Genes and biomarkers that allow doctors to choose the right therapy for the right patient

...response and progression free survival in patients treated with Cetuximab: Abstract 5671 Mutations in the KRAS oncogene could predict a lack of response to the drug cetuximab in patients with colorectal tumors. For those with the mutations, the drug is likely to be inefficient and possibly harmful, acc...

Erectile dysfunction in diabetes is due to selective defect in the brain

...stretch in diabetic rats. Male Sprague-Dawley rats treated with streptozotocin (STZ) to induce diabetes were used as they exhibit sexual and behavioral symptoms similar to those found in diabetic men with sexual dysfunction. The researchers focused on the paraventricular nucleus (PVN) of the hypothalamus...

Dual gene therapy suppresses lung cancer in preclinical test

... of normal cells unaffected. The cancer cell lines treated with the gene combination had 2 to 3 times more cells killed by apoptosis than either gene nanoparticle had individually. The research team then confirmed these findings in the mouse studies. The nanoparticle delivery system, which the researchers...

HIV protein enlisted to help kill cancer cells

...of radiation. When mice with malignant tumors were treated with TAT-Bim, their tumors shrank, and they survived longer than mice that didn't get the treatment. After 40 days, 80 percent of mice receiving TAT-Bim were alive compared to 20 percent of mice that didn't get the treatment. Hawkins asserts that t...

Scientists to track impact of Asian dust and pollution on clouds, weather, climate change

...oss in Alzheimer’s disease, or even depression are treated by fiber optics delivering light to genetically defined populations of nerve cells....

Common blood test can help distinguish between mononucleosis and tonsillitis

...leosis and 100 patients with bacterial tonsillitis treated at their facility. All patients were given the spot test for mononucleosis and additional blood tests were performed to determine the number of lymphocytes (a particular type of white blood cell involved in the body's immune response) and overall wh...

Common algae helps illustrate mammalian brain electrical circuitry

...oss in Alzheimer’s disease, or even depression are treated by fiber optics delivering light to genetically defined populations of nerve cells....

Gene expression test reveals ER and HER-2 status of breast tumors

...am leader with Symmans. ER-positive tumors are treated with estrogen-suppressing drugs such as Tamoxifen. Tumors that are HER-2 positive are sensitive to Herceptin, an antibody-based drug that binds to the HER-2 receptors, blocking them from coupling with growth factors that fuel breast cancer. Last f...

No-scalpel vasectomies by skilled surgeons may speed recovery

...ty. The smaller trial included 100 participants treated at a single site in Denmark. None of the eight doctors had substantial experience in the no-scalpel technique. Training was limited to an instructional video and one supervised procedure. Only one surgeon performed more than 10 no-scalpel vasectomies...

Elderly spinal cord injuries increase five-fold in 30 years, Jefferson neurosurgeons find

...g and blunt spinal cord and spine-injured patients treated at Jefferson Regional Spinal Cord Injury Center over a 28-year period (1978-2006). Overall annual admissions for SCI at Jefferson's Spinal Cord Injury Center have increased 60 percent since the early 1980's, but geriatric SCI admissions have in...

Intravenous nanoparticle gene therapy shows activity in stage IV lung cancer

...astatic non-small cell lung cancer tumors. "We've treated 13 patients in this first-in-human study and we've...ine therapy. All patients on the trial had been treated with front line cisplatin combination chemotherapy, which failed to halt their disease. The clinica...

Napoleon's mysterious death unmasked, UT Southwestern researcher says

...and autopsy reports, memoirs of the physicians who treated Napoleon on the island, eyewitness accounts and me...th Stage IIIA gastric cancer survive five years if treated with modern surgery and chemotherapy. But what might have caused Napoleon's cancer? Risk facto...

Cancer researchers add spice to research against rare neuromuscular disease

...e Medicine, mice carrying the human gene that were treated with ASC-J9 experienced a remarkable improvement. ...ger than the untreated mice. In addition, the mice treated with ASC-J9 were able to mate and produce offspring, while their counterparts could not. ASC-J9 ...

Researchers uncover protection mechanism of radiation-resistant bacterium

...ich could eventually influence how individuals are treated for exposure to chronic or acute doses of radiation; could lead to ways to protect cancer patients from the toxic effects of radiation therapy; and may prove significant in efforts to contain toxic runoff from radioactive Cold War waste sites. Fif...

Knocking out survival protein could aid leukemia treatment

...d conventional treatment. When the researchers treated cells with both siRNA and the drug rituximab, the combination killed significantly more leukemia cells than the drug alone. Overall, says Byrd, "Our data indicate that specifically targeting Mcl1 might be effective in the treatment of CLL, partic...

New research may overturn conventional wisdom on drug-resistant tuberculosis

...y testing to investigate patients with TB who were treated in Shanghai hospitals during 1999-2004. They focus... high rate of primary drug-resistant strains among treated patients," said Dr.Gao. "This overturned the common belief that drug resistance among treated patien...

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