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Tag: "treated" at biology news

Gene thought to assist chemo may help cancer thrive

...ion profiles. Some of the cancer patients had been treated with chemotherapy prior to surgery, and some had n...patients actually had malignant tumors or had been treated with chemotherapy. However, they found that the gene expression profiles of the tumors clustered th...

Leukemia drug turns mini-molecules up, cancer genes down

...al amounts of the two miRNAs to leukemia cells not treated with ATRA. Restoring the miRNAs caused a strong drop in Bcl-2 levels. The researchers then looked at miRNA let-7, a known regulator of the Ras oncogene, and likewise found that high levels of this miRNA were associated with low Ras activity. ...

Mechanism of nicotine's learning effects explored

...rties of neurons in slices of mouse brain, as they treated the slices with nicotine or with drugs that prevent nicotine’s action. Specifically, the researchers studied the neurons of the prefrontal cortex, which contain centers for learning and memory. Researchers had known that nicotine enhances learning...

UC Davis researchers use heated nanoprobes to destroy breast cancer cells in mice

... of AMF bursts. Tumor growth rate slowed in the treated animals, a response that correlated closely with heat dose. No toxicity related to the bioprobes was observed. "Using heat to kill cancer cells isn't a new concept," DeNardo said. "The biggest problems have been how to apply it to the tumor alone,...

Mutation improves memory, may lead to memory-enhancing pill

...avioral memory tests, they show. Moreover, animals treated with a small molecule that had the opposite effect—leading ultimately to an increase in the memory-blocker's concentration—showed signs of memory impairment. "There are very few examples where you can increase memory, especially by deleting genes,...

Woven scaffolds could improve cartilage repair

...built the weaving machine. "The first joints to be treated this way would likely be hips and shoulders, though the approach should work for cartilage damage in any joint." The researchers reported the new technology in the February 2007 issue of the journal Nature Materials. The research was supported by ...

OHSU surgeon implants donated tissue allografts

...tients, suffering with complex joint injury, to be treated in a timely and effective manner," Crawford said. Crawford who performs several cartilage restoration procedures each week has already seen the benefit for his patients. The opportunity to correct disability and restore joint function offers the ...

RNA splicing factor implicated in ovarian tumor cell growth

...overed until its advanced stages. If diagnosed and treated while the cancer is confined to the ovary, the 5-year survival rate is more than 90 percent, according to the American Cancer Society. Unfortunately, only 19 percent of all cases are found in the early stages. One woman in 58 will develop ovarian ...

Study examines risk of soft tissue sarcomas in hereditary retinoblastoma survivors

...nt that most retinoblastoma patients received when treated decades ago. Radiation is used less frequently tod...osed, and most (88.2 percent) of the patients were treated with radiation. A total of 69 soft tissue sarcomas were diagnosed in 68 hereditary retinoblastom...

Hybrid molecule causes cancer cells to self-destruct

...days, however, cancer growth had resumed in dishes treated with four of the compounds. But in samples treated with the butyrate-ManNAc hybrid, all of the cancer cells had died. The researchers also wanted to...

Stem cells act through multiple mechanisms to benefit mice with neurodegenerative disease

... Hex, which reduced the lipid accumulations in the treated animals. The experimental treatment also dampened the inflammation that typically occurs in the brains of most degenerative diseases, including Sandhoff's, and likely contributes to disease progression. "Our studies suggest that functi...

Radiation therapy combo cures prostate cancer long-term

Seventy-four percent of men treated with a combination of radiation seed implants and external beam radiation therapy for prostate cancer are cured of their disease 15 years following their treatment, according to a study released today in the International Journal of Radiation Oncolog...

Chemo combination improves survival in asbestos-related cancer

...sbestos exposure ?have a higher survival rate when treated with a combination of two cancer drugs, a large mu...f 448 patients with advanced mesothelioma who were treated with either the single drug or the combination. "Pemetrexed used in combination with cisplatin si...

Molecular differences between early and advanced melanomas could provide new drug targets

...lanomas that have not spread below the skin can be treated surgically and have a survival rate of 98 percent beyond five years, according to the American Cancer Society. But when melanomas grow downward, the tumors become highly resistant to chemotherapy and radiation and the five-year survival rate falls ra...

Antibody therapy prevents type 1 diabetes in mice

...n adulthood. In this study, the Pitt researchers treated non-obese diabetic (NOD) mice with an antibody -- a type of protein produced by the immune system that recognizes and helps fight infections and other foreign substances in the body -- directed against a receptor known as CD137 on the surface of a ty...

Grape expectations for healthier wine

...s can remain in storage for months and are usually treated with sulphur dioxide to prevent decay. Although the sulphur dioxide is effective, it is corrosive and can cause severe allergic reactions in some people. Wine-makers have a similar problem in that the sulphites added to wines to prolong their shelf-l...

Vasectomy may put men at risk for type of dementia

...esearchers surveyed 47 men with PPA who were being treated at Northwestern's Cognitive Neurology and Alzheimer's Disease Center and 57 men with no cognitive impairment who were community volunteers. They ranged from 55 to 80 years old. Of the non-impaired men, 16 percent had undergone a vasectomy. In cont...

Infection detectives use disease 'fingerprints' to track common infections in children

... admitted and put into the intensive care unit and treated with antibiotics. That’s our goal," said Dr. Ramilo. "This is just the first step. But it establishes a basis for us to do that." While pediatricians couldn’t perform the analysis in their offices, researchers are already thinking about a possible...

Putting an old drug to a new use

...it can lead to organ failure and even death if not treated before irreversible damage has occurred. Researchers from the Innsbruck Medical University, the University of Heidelberg, Germany, and the European Molecular Biology Laboratory (EMBL) now made a surprising discovery that may lead to new therapeutic a...

Researcher to study astronaut bone loss for space biology agency

... the second part, skeletally unloaded rats will be treated with IGF-1 and reloaded on a regular cycle –?much as astronauts might regularly engage in weight-bearing exercise while in orbit –?in order to stimulate integrin production and enhance or recover IGF-1 receptor function. The IGF-1 will act as a signa...

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