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Tag: "treated" at biology news

Experimental RNA-based drug kills prostate cancer cells effectively and safely

...ays. By the end of the study, the tumors in the 10 treated mice had shrunk two-fold in volume, while the tumors in the 10 control animals had more than tripled in size. "The animals themselves showed no signs of side effects," Giangrande said. The scientists caution that much work remains to move the ex...

T cells activated to fight HIV basis for dendritic cell therapeutic vaccine

...ndritic cells. Persons infected with HIV and being treated with antiretroviral drugs can control but not eliminate HIV infection. If the drug therapy is discontinued, the virus comes roaring back. Dr. Rinaldo and others have hypothesized that this is because the drug therapy does not completely restore CD8 c...

Fatty spheres loaded with siRNA shrink ovarian cancer tumors in preclinical trial

...lines derived from women with advanced cancer were treated for 3-5 weeks. They received liposomes that contained either the FAK siRNA, a control siRNA, or were empty. Some mice received siRNA liposomes plus the chemotherapy docetaxel. Mice receiving the FAK-silencing liposome had reductions in mean tumor...

Gene first linked to rare disease may trigger skin cancer, other tumors

...survival. Isolated CYLD-deficient skin cells, when treated with the tumor-inducing chemicals, began to proliferate due to an accumulation of Bcl-3 in the nucleus, they found. Treatment with a single dose of ultraviolet light--thought to be a trigger of cylindromas--sparked the same reaction in the mutant cel...

Pollution threatens coral health by preventing lesions from healing, UCF study shows

...at Risk program has listed coastal development and treated wastewater discharge as chronic problems along Flo...cations at each of four sites: a City of Hollywood treated wastewater outfall, the Port Everglades inlet mouth, a second outfall next to a mouth of the Hillsbo...

New egg freezing technique offers hope to hundreds of women

... also confirmed that some eggs, particularly those treated with EG and with the PrOH agent containing more sucrose, had vacuoles developing ?a process known as vacuolisation. Professor Nottola said: "These data suggest that frozen-thawed oocytes may look similar to fresh oocytes, but when they are examined ...

Injection may prevent infertility in men receiving cancer chemotherapy

...t could be used to avoid testicular damage in mice treated with Taxol. "Clinical studies had already shown that AS101 could protect against bone marrow damage and hair loss, and also sensitises the tumour to treatment", he said. The scientists divided the mice into four groups ?Taxol only, AS101 plus Taxol...

Novel therapy combinations gain ground in treating hepatitis

...Results [Abstract 4] More than half of currently treated hepatitis patients are infected with strains of he...8 weeks of treatment. A total of 81 patients were treated with either CIFN or with pegIFN a2a for 72 weeks, both in combination with RBV. After the initial ...

The molecular mechanism of a diabetes vaccine revealed

...ly harmful T cells available. In addition, T cells treated with p277 cause the delinquent T cells to secrete anti-inflammatory substances instead of the inflammation-causing ones that they usually make which lead to autoimmune disease. This double action of the peptide weakens the damaging activities of the ...

UF scientists restore sight to chickens with blinding disease

...t Brain Institute. "The vision capabilities of the treated animals far exceeded our expectations." The bird ...Later, more precise tests showed that of the seven treated chickens, five displayed near-normal visual behavior. Measurement of electrical activity in the reti...

'Micro-boxes' of water used to study single molecules

...the transfer of energy from one end of a specially treated DNA molecule to the other. Water offers several advantages over other methods for containing single molecules, such as attaching them to surfaces or placing them inside liposomes (artificial cells). The water droplets can be held far from any surfa...

Ever-happy mice may hold key to new treatment of depression

...us; our 'knock-out' mice acted as if they had been treated with antidepressants for at least three weeks." This research represents the first time depression has been eliminated through genetic alteration of an organism. "The discovery of a link between TREK-1 and depression could ultimately lead to the d...

New genetic test for breast cancer

...recisely identify which patients can be adequately treated with hormonal therapy alone and which patients will truly benefit if chemotherapy is added to the treatment," said Joseph Sparano, MD, who directs the Breast Evaluation Center at the Montefiore-Einstein Cancer Center. "With better individualized tre...

Brain enzyme treatment relieves memory lapse in Alzheimer's mice

...shed studies by Shelanski's group found that cells treated with Aß exhibited a rapid drop in Uch-L1, he said.... investigate in the current study, the researchers treated brain slices with a chemical that blocks Uch-L1 function. The treated brain tissue displayed a decli...

Radiation-armed robot rapidly destroys human lung tumors

...eatment of lung tumors which otherwise couldn't be treated with a high dose of radiation due to lack of sufficient real-time tracking accuracy in other, more conventional radiation therapy machines. Treating lung tumors with the enhanced Cyberknife requires only 1-3 sessions lasting 60-90 minutes. In conve...

Drug triggers body's mechanism to reverse aging effect on memory process

...s associated with normal aging." The researchers treated two groups of middle-aged rats twice a day for four days with either a solution that contained ampakines or one that did not. They then studied the hippocampus region of the rats' brains, an area critical for memory and learning. They found that in t...

Mosquito spray increases toxicity of pyrethroids in creek, study finds

...square mile region north of the American River was treated on Aug. 8, 9 and 10, and a 104-square mile area south of the American River was treated Aug. 20, 21 and 22. Sediment and water samples were taken from the northern creeks on Aug. 12, abo...

UC Davis study finds HIV hiding from drugs in gut, preventing immune recovery

...osa, suppressing immune function in patients being treated with antiretroviral therapy--even when blood sampl... Results of the study suggest that patients being treated with antiretroviral therapy should be monitored using gut biopsies and that the gut's immune functio...

Mayo Clinic study finds two genes predict outcome for breast cancer patients

...relapse in hormone-receptor positive breast cancer treated with tamoxifen," says Matthew Goetz, M.D., who co-led the project with James Ingle, M.D. and Fergus Couch, Ph.D. "Our new study shows that the marker is only useful for identifying women with a higher risk in the setting of lymph node-negative breas...

Experimental drug reverses key cognitive deficits, pathology in Alzheimer's

...bilities. One test involved measuring how well the treated animals could learn to find a submerged platform i...of the hippocampus. The researchers found that the treated mice performed significantly better than untreated knockout mice on the task. Significantly, found ...

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