Researchers reveal secret of key protein in brain and heart function
... drug makers to targets for developing new ways to treat cardiac or neurological diseases. "To arrive at a solution, you need to understand the problem," Mierke said. "Solving protein structures opens doors for effective treatments." SAP97 is found mainly in the central nervous system and is known as a "...Cancer drug slows poxvirus in mice
...asic and applied research to prevent, diagnose and treat infectious diseases such as HIV/AIDS and other sexually transmitted infections, influenza, tuberculosis, malaria and illness from potential agents of bioterrorism. NIAID also supports research on transplantation and immune-related illnesses, includin...Cancer related gene p53 not regulated as indicated by previous tissue culture research
...ctivators." Many chemotherapeutical drugs used to treat cancer exert their biological effects on tumor cells through activation of the p53 pathway. Having an accurate view of how p53 is regulated will allow the development of specific drugs that unleash the killing power of p53 by interfering with its neg...Discovery could be key to bioterrorism defense
... towards developing countermeasures to prevent and treat Nipah and Hendra viruses." "Now that we've identi...s peptide can be used as a prophylactic, and/or to treat infections, and antibodies developed using this peptide can be utilized in diagnostic assays. ...Stem cell treatment improves mobility after spinal cord injury
...her approaches using human embryonic stem cells to treat chronic injuries and other disorders of the central nervous system. In previous studies, Keirstead and colleagues identified how the body's immune system attacks and destroys myelin during spinal cord injury or disease states. They also have shown t...Immune system's distress signal tells bacteria when to strike back
...ready learned how to resist the drugs developed to treat them. Scientists are now looking at alternatives, such as ways to block or scramble the chemical messages that allow microbes to eavesdrop on their hosts or to conspire together to mount an attack. "We chose to study this in Pseudomonas because it i...Two studies document rise of superbugs in the environment
...ast one of them," Dr. Pop-Vicas said. "Starting to treat an infection with inadequate therapy is associated with a worse outcome than using adequate therapy from the start," she added. Once the bacterium's drug resistance is known, the therapy can be adjusted accordingly. "We need to learn more about ways...Stem cell therapy successfully treats heart attack in animals
... that stem cell therapy can be used effectively to treat heart attacks, or myocardial infarction, in pigs. In just two months, stem cells harvested from another pig's bone marrow and injected into the animal's damaged heart restored heart function and repaired damaged heart muscle by 50 percent to 75 perce...Diabetic nerve therapy shows 'striking' results
...d with painkillers and antidepressants that do not treat the underlying nerve damage. Progression to amputa...tly, there are no effective therapies available to treat this debilitating and frequent complication of diabetes and patients are generally prescribed painki...Study Finds Moderate Hypothermia A Safe Treatment For Traumatic Brain Injury In Kids
...burgh. "There is no one thing that can effectively treat all cases of traumatic brain injury, but our hope is that with the cooling from hypothermia, we may block or slow down the brain's deleterious biochemical mechanisms following an injury and also be able to develop other more effective treatments." L...New method shows it is possible to grow bone for grafts within a patient's body
...ey use the same method to fuse spinal vertebrae to treat serious spinal injuries and back pain. Although this works well at the repair site, the removal operation is extremely painful and can produce serious complications. If the new method is confirmed in clinical studies, it will become possible to grow ...Researchers discover mechanism for multiplying adult stem cells
...tomize" embryonic stem cells that could be used to treat diseases such as diabetes or Parkinson's. ...Scientists reveal how disease bacterium survives inside immune system cell
...ds, could help researchers develop therapeutics to treat or prevent bacterial infections. ...Genetic links could unlock clues to leading cause of blindness
...dictors of macular degeneration could help doctors treat the disease before extensive vision loss occurs an...l happen) if we don't come up with a better way to treat this," she said. That's where Dawson thinks the monkeys can help. They age three to four times fast...Scientists succeed in cloning human embryos from eggs matured in the lab
...from women seeking fertility treatment are used to treat the patient. Immature oocytes are not used routinely for treatment at present, and so any that are retrieved can be donated for research. These immature oocytes are arrested in the prophase I stage, before meiotic division is complete, when the enlar...Invitrogen Launches i-Path -- A Unique Systems Biology Platform at BIO 2005
...from women seeking fertility treatment are used to treat the patient. Immature oocytes are not used routinely for treatment at present, and so any that are retrieved can be donated for research. These immature oocytes are arrested in the prophase I stage, before meiotic division is complete, when the enlar...Newly discovered genetic disease sheds light on body's water balance
...atients. "When adults retain too much water we can treat them by restricting fluid intake," he said. "We can't do that with infants -- almost all of their nutrition comes in liquid form." The physicians were reluctant to use other medications that generate increased water loss in the kidneys, as these can...International Team Determines Geographic Origin of Leprosy
... may help public health officials better track and treat leprosy, which remains a significant problem in so...returned. This, in turn, will aid efforts to fully treat patients so that the bacteria are completely eliminated. Reference: M Monet et al. On the origin of...Purdue scientists may have found key to halting spinal cord damage
... development for other conditions could be used to treat neurodegenerative diseases as well. "Hypertension...like to see whether they also could be modified to treat the conditions we are interested in." Further research will be necessary to determine how great a r...New insights into how Huntington's disease attacks the brain
...nowledge may lead to new therapeutic strategies to treat Huntington's disease." Huntington's disease is a genetic brain disorder that usually strikes in mid-life, but can also attack the elderly and children as young as 2. Slowly depriving a person of their ability to think, speak, walk and swallow, the d...