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Tag: "treat" at biology news

Buying Time Through Hibernation on Demand

... in a mammal, ultimately could lead to new ways to treat cancer and prevent injury and death from insufficient blood supply to organs and tissues. "We are, in essence, temporarily converting mice from warm-blooded to cold-blooded creatures, which is exactly the same thing that happens naturally when mamma...

Anti cancer virotherapy well tolerated in first human administration, research finds

...ating as potential therapies for different hard to treat malignancies including melanoma and ovarian cancer. These viruses occur naturally and routinely in the community causing mild infections in adult humans. Previously the Shafren group has published research on CVA21 that showed success in specifical...

U-M team recovers ancient whale in Egyptian desert

... in a mammal, ultimately could lead to new ways to treat cancer and prevent injury and death from insufficient blood supply to organs and tissues. "We are, in essence, temporarily converting mice from warm-blooded to cold-blooded creatures, which is exactly the same thing that happens naturally when mamma...

Researchers report new pro-inflammatory role for anti-inflammatory enzyme

...s discovery may eventually provide a new target to treat sepsis, which is caused by overproduction of nitri... companies have been developing iNOS inhibitors to treat sepsis," explains Dr. Hobbs. "However, it now appears as if these are ineffective in reducing the mo...

Discovery may lead to better Candidiasis drug

...lthy people, said Edgerton, but it is difficult to treat in persons with compromised immunity and can be deadly if it infects vital organs. Researchers were aware that histatin usually can keep Candida albicans in check in persons with enough saliva and a healthy immune system, but they did not know preci...

Emergence of cancer as major cause of childhood death in developing countries is not being adequately addressed

...rts of Africa it might be possible to successfully treat children who have Burkitt’s lymphoma using a single drug, cyclophosphamide. Such twinning projects can be supported initially by the partner in the more affluent country, the authors say. Local charitable groups can raise funds to support an oncology...

UNC launches study of liver injury caused by drugs

...help to develop better ways to prevent, detect and treat this growing problem," Watkins said. DILIN also may provide important insight into medical problems beyond liver injury induced by drugs, he added. "Drug-induced liver injury is an ideal model to study how genes and environment interact to produce ...

Study: 'homemade' gene expression technology unreliable

...y pinpoint genes affected by drugs being tested to treat heart disease, mental illness, infectious diseases and cancer. In the past, researchers were only able to analyze a few genes at once, and they were often uncertain whether these were of greatest importance. Spencer's group is using the technology i...

NIH Researchers Discover How Insulin Allows Entry of Glucose Into Cells

...e with the cell membrane might yield a new drug to treat insulin-related disorders. He added that each step in the process might provide the basis for a treatment: when the vesicles first stop moving, when they tether to the inside of the cell’s membrane, and when they fuse with the membrane. Next, the re...

Shutting down the HIV assembly line

...-3 interaction and that may lead to new efforts to treat HIV infection," Spearman said. Such drugs should be very specific, he said, since it should be possible to block Gag's interaction with AP-3 without disrupting AP-3 function in the cell. And by targeting an early step in HIV particle assembly, an in...

Turning viruses into allies against cancer

...e cells to other parts of the body. "This aims to treat metastatic disease and reduce tumor recurrence," s...p iodine in the thyroid gland, is being studied to treat human liver cancer cells grafted in an animal model. Scientists at the Mayo Clinic in Rochester, Mi...

Novel gene-silencing nanoparticles shown to inhibit Ewing's sarcoma

... with hopes of creating a new and effective way to treat Ewing's sarcoma and other tumors in the clinic. "Clinically, Ewing's patients are treated with combination of chemotherapeutic agents, but despite aggressive treatments, the patient outcomes are poor," said Hu. "The delivery system we're developing...

Chromosome Deletion Predicts Aggressive Neuroblastoma

...entifying the correct risk level allows doctors to treat aggressive cancers appropriately, while not subjecting children with low-risk cancer to overtreatment. Oncologists know that amplification, an abnormal increase in the number of copies, of a cancer-causing gene called MYCN heralds a high-risk, aggre...

Researchers find promising cancer-fighting power of synthetic cell-signaling molecule

...ls leads us to hope these may be a new approach to treat cancer." However, human trials must still be done to determine safety and efficacy in people, the researchers cautioned. The findings will be presented by Georgia Tech postdoctoral researcher Qiong Peng on April 19 in a "late-breaking" poster at the...

UN votes to ban human cloning

...enabled researchers to develop innovative drugs to treat diseases." The United Kingdom, the Russian Federation, France and India, have not reached a consensus on banning reproductive cloning and want to keep their options open on therapeutic cloning. Britain who voted against,echoed the views of a number ...

Genetic therapy reverses nervous system damage in animal model of inherited human disease

...d to humans, say the researchers, it might one day treat an entire class of diseases called lysosomal storage disorders which cause severe, sometimes fatal, disabilities in about one in 5,000 births. The members of the research team from the University of Pennsylvania School of Veterinary Medicine, the Chi...

Study reveals dramatic difference between breast cancers in US and Africa

...st cancer, as well as how we prevent it and how we treat it," she added. "The guidelines were developed based on our deep knowledge of breast cancer in older women of European ancestry, but our results mean that much of the U.S. and European data simply do not apply to the types of breast cancer we most co...

OneWorld Health drug receives 'Orphan' designation from U.S. and European regulatory agencies

...n of Medicinal Products (EMEA), for paromomycin to treat visceral leishmaniasis (VL). VL, also known as ka...pprovals in countries that have a critical need to treat VL." Paromomycin is an off-patent aminoglycoside antibiotic first used in the 1960s and is still ma...

Measuring Enzymes At End Of Cancer Pathway Predicts Outcome Of Tarceva, Taxol

...ectively kill breast cancer cells. Taxol, used to treat a wide spectrum of cancers, works by interrupting the reorganization of the cell that is necessary if it is to divide. While it was known that the primary effect of the drug is to interfere with assembly of the spindle that pulls nuclear chromosomes ...

FDA Warns About Antipsychotic Drugs and Elderly

... and mania, but clinical studies of these drugs to treat behavioral disorders in elderly patients with dementia have shown a higher death rate associated with their use compared to patients receiving a placebo (sugar pill). Today's advisory applies to such antipsychotic drugs as Abilify (aripiprazole), Zy...

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