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Tag: "treat" at biology news

A new mechanism of regulating RNA degradation

...of gene expression in cells to create therapies to treat disease. While cells have a variety of ways to control gene expression, the trick for players in this game is to recognize them amidst the incredibly complex background of cellular machinery. Now, in a paper in the January 28th issue of Cell, Lynne ...

FDA Approves Human Hookworm Vaccine for Phase I Safety Trials

...of gene expression in cells to create therapies to treat disease. While cells have a variety of ways to control gene expression, the trick for players in this game is to recognize them amidst the incredibly complex background of cellular machinery. Now, in a paper in the January 28th issue of Cell, Lynne ...

University of Manchester makes made-to-measure skin and bones a reality using inkjet printers

...e-to-measure skin and bones, which couldbe used to treat burn victims or patients who have suffered severedisfigurements, may soon be a reality using inkjets which can printhuman cells.Scientists at The University of Manchester have developed thebreakthrough technology which will allow tailor-made tissues ...

W.M. Keck Foundation funds study of friendly microbes

...as well as help create new methods to diagnose and treat patients with common and uncommon diseases. "The CGS represents a community of faculty and students with expertise in the biological, computational and physical sciences," Gordon says. "We are dedicated to integrating concepts and technologies from ...

Controversial drug shown to act on brain protein to cut alcohol use

...hould allow development of a new class of drugs to treat addictionwithout Ibogaine's side effects," said Dorit Ron, PhD, UCSF associateprofessor of neurology and also principal investigator at the GalloCenter. Ron is co-senior author of the paper with Patricia Janak, PhD,UCSF assistant professor of neurolo...

Combination therapy boosts effectiveness of telomere-directed cancer cell death

...n reality. Its the case of telomerase inhibitorsto treat cancer; they are supposed to strip the "immortal" (able todivide indefinitely) aspect of cancer cells. Yet, something in the cellseems to block their function, preventing them to inhibit completelythe telomerase. What to do then? Scrap the project? L...

GATA: a graphic alignment tool for comparative sequence analysis

...n reality. Its the case of telomerase inhibitorsto treat cancer; they are supposed to strip the "immortal" (able todivide indefinitely) aspect of cancer cells. Yet, something in the cellseems to block their function, preventing them to inhibit completelythe telomerase. What to do then? Scrap the project? L...

Research on Worms Yields Clues on Aging

...dicine in St. Louis. When exposed to drugs used to treat epilepsy inhumans, worms lived longer and retained youthful functions longer thannormal.Because the drugs affect nerve signals, the researchers' observationssuggest that the nervous system influences aging processes. Thefindings are reported in the J...

Genome-wide mouse study yields link to human leukemia

...s given us a whole new way to look at and possibly treat leukemia," says Michael Caligiuri, director of the OSU Comprehensive Cancer Center (OSUCCC) and senior co-author of the study. "It's also validated our mouse model as a good predictor of what happens in the development of human disease," he added. T...

Leukemia Drug Breakthrough Study In New England Journal Of Medicine

...g Revlimid showing promise as an innovative way to treat patients with myelodysplastic syndrome (MDS), a fo...on (NDA) for Revlimid as an innovative approach to treat the anemia of MDS patients with the 5q minus deletion. In 2001, the National Cancer Institute award...

Gene therapy converts dead bone graft to new, living tissue

... turned on the genes. The mouse body then began to treat the implanted bone as if it were its own tissue instead of a foreign object, which would normally trigger the body to wrap the "invader" in scar tissue. "That recognition is the key," says Schwarz. "It's at that point that the body actually begins c...

Antibiotic Resistant Bacterium Uses Sonar-like Strategy to “See?Enemies or Prey

...f hospital-acquiredinfections, to find new ways to treat them. These infections arefrequently resistant to many, and sometimes all, antibiotics. Tens ofthousands of deaths due to antibiotic resistant infection occur eachyear in the US, adding an estimated $ 4 Billion to health care costs.Scientist have kno...

Solution to Pollution: New Bacteria Eats Toxic Waste

...h bioremediation is the most cost-effective way to treat the contaminated sediments.?/p> The research involves many levels of cooperation between the sciences and engineering fields but also extends to social scientists and economists. Utah State undergraduates and graduate students from the Colleges o...

BRCA1 causes ovarian cancer through indirect, biochemical route

...ts and physicians trying to figure out new ways to treat ovarian cancer. If the cancer had arisen in the same cells that had the BRCA1 mutation, the only way to interfere would be to correct the mutation. In this case, however, there's a mediator-a biochemical of some sort-that scientists might be able to ...

Purdue proves concept of using nano-materials for drug discovery

...o test the potential effectiveness of new drugs to treat diseases. Membranes, which surround cells and regu...ich is very important because many future drugs to treat diseases will likely work by controlling proteins in cell membranes." Researchers tested the device...

Scientists discover the cellular roots of graying hair

...g drugs to mimic the aging process, tosuccessfully treat melanoma.?The team also made mice lacking a gene, MITF that regulates Bcl2. Thesemice also went gray, but more gradually than did the mice that had noBcl2. The loss of MITF activity, the investigators say, appears to beimplicated in the mistaken diff...

Fundamental Finding Yields Insight into Stem Cells, Cancer; Opens Door to Drug Discovery

...g drugs to mimic the aging process, tosuccessfully treat melanoma.?The team also made mice lacking a gene, MITF that regulates Bcl2. Thesemice also went gray, but more gradually than did the mice that had noBcl2. The loss of MITF activity, the investigators say, appears to beimplicated in the mistaken diff...

Weizmann Institute scientists develop a new approach for directing treatment to metastasized prostate cancer in the bones.

...g drugs to mimic the aging process, tosuccessfully treat melanoma.?The team also made mice lacking a gene, MITF that regulates Bcl2. Thesemice also went gray, but more gradually than did the mice that had noBcl2. The loss of MITF activity, the investigators say, appears to beimplicated in the mistaken diff...

First-ever Compounds To Target Only Metastatic Cells Are Highly Effective Against Breast, Prostate, And Colon Cancers

...ary tumor. "If we had the luxury of time, we could treat that primary tumor at lower doses, too, with fewer side effects for the patient," Dr. Huang said. Until now, agents that specifically target metastatic cells have remained elusive. However, a new avenue of research opened up when Dr. Huang's team no...

Taking Aim With Nanoparticle PEBBLEs

...g encouraging preliminary results using PEBBLEs to treat a virulent form of brain cancer in rats. PEBBLEs are polymer spheres, typically 20 to 200 nanometers in diameter—about the size of a virus. The spheres carry an assortment of molecules on their surfaces, some to guide the PEBBLEs to their targets in...

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