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Tag: "transposable" at biology news

Researchers uncover sequence of major rice pathogen

...en subject to invasion and proliferation of active transposable elements, reflecting the clonal nature of this fungus imposed by widespread rice cultivation. ...

New tumor-suppressor gene discovered

...ssing pie ce of genetic material caused by another transposable element jumping out and dragging lots of material along with it. "With such a deletion of material, this gene is basically gone, so we knew it couldn't possibly function at all," Lai says. Both kinds of mutations resulted in the formation of the same...

Study reveals candidate targets for anti-retroviral therapeutics

...udding yeast, these mobile elements (called Ty ?or transposable yeast ?elements) encode proteins that are homologs of retroviral proteins. The proteins encoded by Ty elements and the steps of the life cycle in yeast are similar to the proteins encoded by retroviruses and their life cycles in animal cells. Scienti...

The genetic origins of corn on the cob

...molecular genetics. The former included our use of transposable elements or 'jumping genes'--discovered at Cold Spring Harbor by [Nobel laureate] Barbara McClintock--to 'tag' the ramosa1 gene. That enabled us to isolate the gene and determine its DNA sequence for a variety of other experiments." "As corn was bei...

$6.5 Million Grant for Microarray Center at Yale School of Medicine

...molecular genetics. The former included our use of transposable elements or 'jumping genes'--discovered at Cold Spring Harbor by [Nobel laureate] Barbara McClintock--to 'tag' the ramosa1 gene. That enabled us to isolate the gene and determine its DNA sequence for a variety of other experiments." "As corn was bei...

'Jumping genes' contribute to the uniqueness of individual brains

... dismissed as useless gibberish or "junk" DNA, the transposable L1 elements were thought to be intracellular parasites or leftovers from our distant evolutionary past. It has been known for a long time that L1 elements are active in testis and ovaries, which explains how they potentially play a role in evolution...

Where 'jumping genes' fear to tread

...ts (greater than 10 kilobases in length) that lack transposable elements. His team identified 860 such sequences ...cause it is a marsupial that has a similar load of transposable elements compared to mice and humans but is evolutionarily distant from the two species. In contras...

Pathway toward gene silencing described in plants

...thylation is to turn off repetitive genes, such as transposable elements that can move or spread throughout a genome and disrupt other gene functions if left unchecked. There is also interest in DNA methylation because understanding how some genes are selectively silenced and how silenced alleles can be turned on...

Sunflower speciation highlights roles for transposable elements in evolution

...massive proliferation of genetic entities known as transposable elements. The findings are reported by Mark Ungere...ies are associated with a massive proliferation of transposable genetic elements that has occurred independently in the genome of each hybrid species. Transposable ...

Taking 'chips' to the next level of gene hunting

... Boeke and his team have focused particularly on transposable elements, segments of DNA that hop around from chr...an genome, which contains hundreds of thousands of transposable elements of which perhaps a few hundred are actively moving around, the yeast genome contains only a...

Does evolution select for faster evolvers?

...e because bacteria and viruses constantly exchange transposable chunks of DNA between species, thus making it possible for life forms to evolve faster than they would if they relied only on sexual selection or random genetic mutations. "We have developed the first exact solution of a mathematical model of evol...

Genome of yellow fever/dengue fever mosquito sequenced

...n the United States, Spain, and France to annotate transposable elements (TEs) in the Ae. aegypti genome. TEs are ...aboratory, uncovered and described more than 1,000 transposable elements, which occupy approximately 50 percent of the entire Ae. aegypti genome. For example, a tra...

Exploring the dark matter of the genome

...ional elements, such as small RNAs that neutralize transposable elements, or transposons -- DNAs similar to viruse...dibly repeat-rich," says Smith, "and most of it is transposable elements that have been chewed up and fragmented." Susan Celniker emphasizes that transposable e...

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