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Tag: "transplants" at biology news

Research shows cord blood comparable to matched bone marrow

...esota researchers report that umbilical cord blood transplants may offer blood cancer patients better outcomes th...ukemia patients who received unrelated bone marrow transplants with those who received umbilical cord transplants. While all bone marrow donors were matched, nearl...

Human stem cell treatment restores motor function in paralyzed rats

...d, with similar results. “Other human stem cell transplants in the spinal cord have focused on repairing the myelin-forming cells,” said co-author Karl Johe, a researcher at Neuralstem, the company that manufactures the hSSCs used in the study. “In this study, we succeeded at reconstructing the neural circuit...

Machine preservation may promote more organ sharing

...ion. The current study included 120 ECD kidney transplants -- 95 kidneys were preserved with machine and 25 with simple cold storage preservation techniques. Despite the fact that the machine-preserved kidneys were out of the body for a longer period of time (a mean of 24 hours versus 19 hours for the c...

Cancer patients monitor fatigue in real time

...ng fatigue in cancer patients undergoing stem cell transplants using a method successfully used to monitor behaviors such as smoking cessation and alcohol use. The method is called "ecological momentary assessment" (often referred to as real-time assessment), which provides an instant measurement of patients'...

Implanting dopamine generators in brain cells obtains improvement in Parkinson's in monkeys

...in monkeys with Parkinson's and which had received transplants was demonstrated to last for at least a year. The research team concluded that the mechanism by which the implants in the striate area of the brain of dopamine-generating cells manage to ameliorate Parkinson's appears to be related to the capacit...

Investigating the measles virus as a tool to kill multiple myeloma

...ave had allogeneic (from another person) stem cell transplants and must either have had a prior measles infection or been vaccinated against it. In the 1970s, measles infections were observed to cause regression of pre-existing cancerous tumors in children. This information was noted, but nothing was done to...

OHSU surgeon implants donated tissue allografts

...fts for transplantation. "Live or fresh tissue transplants are difficult to obtain and complicated to prepare and coordinate. This new cooperation will allow many more of our patients, suffering with complex joint injury, to be treated in a timely and effective manner," Crawford said. Crawford who perfor...

Researchers first to map gene that regulates adult stem cell growth

... in blood marrow transplants. Currently, stem cell transplants with cord blood can only be used in children because cord blood does not contain enough stem cells for an amount needed to be transplanted into an adult. The only stem cell population that has been examined for effects of Latexin to date is in bone...

Stem cell transplants explored at Stanford as a possible treatment for hearing loss

...two different approaches - new drugs and stem cell transplants - are important because drug treatments are unlikely to help everyone. For some people with genetically caused hearing disorders, he explained, no drug is likely to help. "For them, stem cell transplantation may be the answer," he said But for...

Penn researchers replace organ in adult mice using 'single-parent' stem cells

...e to rescue other irradiated mice with bone marrow transplants from these animals. It is clear proof, according to McLaughlin, that uniparental cells could produce hematopoietic stem cells. In addition, McLaughlin's group found no evidence of disease linked to the transplanted cells. In another finding crit...

Scientists discover new virus caused deaths of transplant recipients from single donor

... existing screening methods. Over 30,000 organ transplants are performed in the U.S. each year. Knowledge of the genetic sequence of this virus will enable improvements in screening that will enhance the safety of transplantation. Ian Lipkin, MD, director of the Greene Laboratory and Principal Investigat...

Protein may hold key to decreasing organ dysfunction rates in heart transplants

... response and increasing the success rate of heart transplants worldwide. The study appears in American Journal of Transplantation. Building on earlier work, the study finds that Lcn-2 is released by inflammatory cells attacking transplanted hearts in mice, and suggests that the protein is responsible for attra...

Proteins may predict lung transplant rejection

...rrently, there is no reliable way to predict which transplants will fail, and when signs of chronic rejection app...ng. Disease disturbs protein function Lung transplants are a common therapy for many end-stage lung diseases such as chronic obstructive pulmonary disease,...

Transplanted brain cells hold promise for Parkinson's disease

...earchers already have begun studies that delay the transplants until weeks after injury. For this study, resea...se that had a transplant. Animals that received transplants essentially regained control of their movement, placebo-treated animals did not recover and those th...

Transplanted photoreceptor precursor cells restore visual function in mice with retinal degeneration

...l begin to see the first steps toward retinal cell transplants for people with blinding eye disease," says Swaroop. ...

Artificial cornea offers better results for infants, some blind patients

...n of a group of people for whom traditional cornea transplants usually fail. The new work, supported in part by R...rgical procedures, including 39 traditional cornea transplants that had failed, before the latest implant. In the new study, two of the children received another t...

An artificial cornea is in sight, thanks to biomimetic hydrogels

...t step. The current source of tissue for corneal transplants is cadavers. Donor tissue has problems, Ta notes, ...but they are only used in last-ditch efforts [when transplants are rejected]," he notes. Stanford's artificial cornea is "the most biomimetic," he says, with a wat...

Long-term cancer risk follows stem cell transplant recipients

... 926 patients treated with myeloablative stem cell transplants over an 18-year period. They found that at their institution the 10-year incidence of second cancers in these patients was 3.1 percent. When nonmelanoma skin cancer and carcinoma in situ of the cervix were excluded, incidence was 2.3 percent. That...

International team analyzes human genetic variation in key immune region

...called "HLA typing") in patients who receive organ transplants or suffer from autoimmune disease. Importantly, the researchers' data and analyses, which are made available online to the entire scientific community, provide the tools needed to begin the initial efforts toward identifying genetic risk factors in...

MUHC announces a transplant first in Quebec

...re professionals. The MUHC conducts the most organ transplants in Quebec and has the most comprehensive multi-org...nt program in the province. "Combined heart/liver transplants are so rare that the best technique for a combined implantation has not yet been elucidated," says D...

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