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Tag: "transplanted" at biology news

Gradient guides nerve growth down spinal cord

...generation. If Wnt proteins could be used to guide transplanted nerve cells -- or someday, embryonic stem cells -- to restore the connections between the body and the brain, "it could revolutionize treatment of patients with paralyzing injuries to these nerves," Zou suggests. "Although half the battle is acquiri...

Researchers propose measures to curb lion attacks in Tanzania

...elihood of such cells being rejected when they are transplanted into people with liver disease, for example." The team has taken its first steps towards proving its claims by growing defined liver tissue using the new cell type. By making use of special NASA-derived technology, the team is able to cultivate grea...

Insight into the processes of 'positive' and 'negative' learners

...elihood of such cells being rejected when they are transplanted into people with liver disease, for example." The team has taken its first steps towards proving its claims by growing defined liver tissue using the new cell type. By making use of special NASA-derived technology, the team is able to cultivate grea...

Researchers make 'embryonic-like' stem cells from umbilical cord blood

...elihood of such cells being rejected when they are transplanted into people with liver disease, for example." The team has taken its first steps towards proving its claims by growing defined liver tissue using the new cell type. By making use of special NASA-derived technology, the team is able to cultivate grea...

Researchers identify genes associated with lung transplant rejection

...OB), the most common cause of long-term failure of transplanted lungs. The researchers hope their results will le...is, scar tissue forms in breathing passages of the transplanted lung, narrowing them and eventually making it impossible for the recipient to breathe. The exact cau...

Monkeying around to improve organ transplantation

...pecific suppression of the T cells that attack the transplanted organ is needed. It was known that anergic T cells (immune T cells that do not respond to antigen stimulation) generated in an artificial environment outside the living organism have immunosuppressive activity in vitro. Now in a study appearing onli...

Discovery of T-cell 'traffic control' boosts new drug promise

...mise of similar strategies to prevent rejection of transplanted organs and tissues without compromising essential ...n effect would prevent T cells from swamping newly transplanted organs or launching a harmful autoimmune reaction, the scientists suggest in the paper. They think ...

Stem Cells Found In Cerebellum; Possible Cell of Origin for Childhood Brain Tumors

...te all the major cell types in the cerebellum when transplanted into the cerebellum of neonatal mice. Identifying stem cells in the cerebellum provides the research team with a target for studying both normal development and cancerous growth, said Lee. Other research teams have shown that certain genes are mutat...

New type of rejection blocker protects kidneys after transplant

...ased on blocking the immune system's reaction to a transplanted organ without hampering the body's ability to figh... new principle of inducing immune tolerance of the transplanted organ. If belatacept and similar drugs live up to their promise, they will usher in a new paradigm f...

New complete muscle grown in the lab

...ompletely replace an abdominal muscle segment. The transplanted muscle continued to grow and develop within the mice's bodies. Endowing the muscle tissue with its own blood supply boosted the new tissue's chance of survival and of connecting seamlessly with the mice's own blood vessel networks, they concluded. ...

Discoveries by UAB and Florida scientists may help transplanted organs survive longer

...of a potent molecule that could delay rejection of transplanted organs by preventing blood-vessel deterioration. ...of at least several additional years of health for transplanted organs." A key to the single-injection strategy, Atkinson said, "was the use of adeno-associated vi...

Combination therapy leads to partial recovery from spinal cord injury in rats

...ter the combined treatment showed that many of the transplanted cells survived and migrated within the cord and th...erapy with additional genetic modifications to the transplanted cells, and they plan to test similar techniques that start with undifferentiated embryonic stem (ES)...

Candida albicans Genome Fully Annotated

...pulmonary injury from infections, rejection of the transplanted lung, ischemia, and other factors that damage the alveoli ?tiny hollow sacs along the airways where the blood takes in oxygen and discards carbon dioxide. The processes by which alveoli recover from damage are complex and incompletely understood, Za...

Circulating stem cells play small role in lung repair

...pulmonary injury from infections, rejection of the transplanted lung, ischemia, and other factors that damage the alveoli ?tiny hollow sacs along the airways where the blood takes in oxygen and discards carbon dioxide. The processes by which alveoli recover from damage are complex and incompletely understood, Za...

Precise Timing Enabled Pig-to-rat Transplants To Cure Diabetes

...need for immune suppression. The pig primordia are transplanted into the omentum, a membrane that envelopes the intestines and other digestive organs. When the primordia mature, they replace the missing rat insulin with pig insulin, returning the rats' blood glucose to normal levels. "The absence of a need for i...

Stem cell research - new cell lines

...se from human embryonic stem cells, so they can be transplanted straight into the affected area of a patient. "The insulin-producing cells, which are derived from the layer which also forms the gut and liver are the holy grail for diabetes researchers," said Dr Sidhu. "That's because they are destroyed in type-1...

Infants with Rare Genetic Disease Saved By Cord Blood Stem Cells

...orld ?147 children in all. The oldest Duke patient transplanted for a lysosomal storage disease is now seven years...to preserving brain and motor function." Children transplanted after onset of symptoms do stabilize but exhibit minimal neurologic improvement, said Maria Luisa Es...

Scientists discover that three overlapping signals in embryo help get the backbone right

... "The piece they cut out from the donor embryo and transplanted into the host embryo was able to redefine the stru...other head, brain and spinal cord. The tissue they transplanted sent signals to the host to create these new structures." Since then, scientists have searched for ...

Infants With Rare Genetic Disease Saved by Cord Blood Stem Cells

...orld ?147 children in all. The oldest Duke patient transplanted for a lysosomal storage disease is now seven years...to preserving brain and motor function." Children transplanted after onset of symptoms do stabilize but exhibit minimal neurologic improvement, said Maria Luisa Es...

Multi-purpose protein regulates new protein synthesis and immune cell development

...f blood and immune cells ?than normal mice. Zhang transplanted hematopoietic stem cells from IRE1 knock-out embry...stitute all types of blood and immune cells in the transplanted mice, but their mature B lymphocytes were defective. Without IRE1, lymphocytes don't develop a B cel...

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