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Tag: "transplanted" at biology news

Carnegie Mellon develops non-invasive technique to detect transplant rejection at cellular level

...g (MRI) to track immune cells as they infiltrate a transplanted heart in the early stages of organ rejection. This...ages) as well as other pathological changes in the transplanted heart tissue that indicate the graft is being rejected by the body's immune system. These procedure...

Diabetes researchers pioneer islet cell xenotransplantation in primate studies

...y and the Emory Transplant Center has successfully transplanted insulin-producing neonatal porcine islet cells int...eata developed at the U of A, the researchers then transplanted islets comprised of endocrine and endocrine precursor cells into the monkeys. In vivo, these cells h...

Primates harvest bee nests in Ugandan reserve

... the very defensive tropical African honeybee, was transplanted from Africa to Brazil as part of a scientific experiment to boost honey production in 1956. From Brazil, it invaded the Americas, working its way northward and is now found in southern U.S. states. Dave Roubik has followed the progress of Africani...

Infant transplant patients resist infections that kill adult AIDS patients

...eases that adult AIDS patients do, even though the transplanted infants are basically a model of AIDS. In fact, the post-transplant patients do very well resisting infections. It seemed to us very important to understand why this is so, because maybe that would help us help people with age-related diseases caused...

Engineered Stem Cells Show Promise For Sneaking Drugs Into The Brain

...rate that engineered human brain progenitor cells, transplanted into the brains of rats and monkeys, can effective... the new Wisconsin study, the GDNF-producing cells transplanted in the striatum of animals with a condition like Parkinson's showed not only that a critical drug co...

From one cell, many possible cures

... -- and allow faster growth of tissues that can be transplanted into patients. Teng Ma, an assistant professor of chemical and biomedical engineering at the Florida A&M University-FSU College of Engineering, and colleagues have created a device called a perfusion bioreactor that is designed to mimic conditio...

Sperm stem cells closer to being like embryonic stem cells

... also froze the sperm stem cells, thawed them, and transplanted them back into rat testes, where they developed into normal sperm. Dr. David Garbers, professor of pharmacology, director of the Green Center and senior author of a study appearing in an upcoming issue of the Proceedings of the National Academy of S...

Scientists use stem cells to grow cartilage

...ed new cartilage, showing they can be successfully transplanted in living tissue. The scientists also believe this technique could be used in cosmetic and reconstructive surgery. When removing head and neck cancers, surgeons often have to cut away parts of cartilage, and then take grafts from other parts of the...

New neurons take baby steps in the adult brain

...crease neuron regeneration in the brain or to make transplanted stem cells form connections more efficiently. The researchers, including postdoctoral fellows Shaoyu Ge and Eyleen Goh, discovered that a constant flood of GABA is required as a first step. Next, the new neuron receives specific connections that com...

Scientists discover the molecular switch for nerve cells' insulating jelly rolls

... neurons do. In the first set of experiments, they transplanted unmyelinated axons from the peripheral nervous system (outside of the brain and spinal cord) of embryonic mice into laboratory dishes. They then added Schwann cells to the dishes. They observed that the Schwann cells sat on the axons and did not prod...

A little telomerase isn't enough

...longer the telomeres are to start with, the longer transplanted stem cells will be able to divide and the more likely the transplant is to succeed," explains Greider. To engineer the half-telomerase mice, Ling-Yang Hao, then a graduate student, knocked out one copy of the telomerase gene in non-laboratory mice, ...

Restoring silenced suppressor gene kills lung-cancer cells

...ing the growth of human lung tumors that have been transplanted into mice. The findings are published online in ...'d added working copies of the WWOX gene, and they transplanted the cells into mice; a second group of control mice received lung-cancer cells without the WWOX gene...

A new link between stem cells and tumors

..., we had a tumor." When these altered cells were transplanted into flies, the results were swift and dramatic. The tissue containing the altered cells grew to 100 times its initial size; cells invaded other tissues, and death followed. The growing tumor became "immortal", Caussinus says; cells could be retransp...

New vaccine platform may fight infections with causes from influenza to bioterrorism

...nt function of CD4+ T-cells, such as patients with transplanted organs, HIV and children with leukemia. Without normal reservoirs of these particular T-cells that are key to immune responses, these patients are unable to stave off an infection that in most people causes, at most, a bad cold. The findings are be...

New cell transplantation technique restores insulin production in diabetics

...s the immune system, so that the body accepted the transplanted cells," Dr. Krishnamoorthy said. "We also develope...ve medications to keep the body from rejecting the transplanted islet cells. Type 1 diabetes, formerly known as juvenile diabetes, is a debilitating disease that i...

Bone marrow stem cells may heal hearts even years after heart attacks

...be noted that until now only 18 patients have been transplanted and were compared to a representative control group. This means that we need to concentrate on a larger, prospective randomized controlled trial in order to strengthen the statistical power of the positive results," Dr. Strauer said. Larger trials a...

Research casts doubt on circulating stem cells

...ig. The hope of the medical scientists is that the transplanted stem cells will find their way through the blood into damaged muscle fibres where they can produce functioning dystrophin. The Bonn researcher team was in fact able to detect green-fluorescent stem cell nuclei in the muscle fibre for several months a...

U-M scientists discover identifying markers for primitive blood-forming stem cells

...essed on hematopoietic stem cells, Kiel and Yilmaz transplanted CD150+ and CD150- cells into laboratory mice whose bone marrow had been destroyed by lethal doses of radiation. Healthy bone marrow was restored in six of six mice receiving CD150+ cells, but reconstitution was successful in only one of nine mice rec...

Discarded placentas deliver researchers promising cells similar to embryonic stem cells

...he main concerns about stem cell therapies is that transplanted stem cells would replicate in the recipient to form tumors," noted Toshio Miki, M.D., Ph.D., first author of the paper and an instructor in the department of pathology at the School of Medicine. To help determine if amnion-derived cells that are del...

Israeli scientists successfully transplant frozen-thawed ovaries in sheep

... Human Reproduction[1] that they have successfully transplanted whole frozen and thawed ovaries in sheep, retrieve...gnetic resonance imaging (MRI) on one sheep with a transplanted ovary and one untreated control sheep. It showed that the transplanted ovary contained small oocyte ...

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