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Tag: "transplanted" at biology news

Transplanted photoreceptor precursor cells restore visual function in mice with retinal degeneration

Scientists have successfully transplanted light-sensing cells called photoreceptors directly...ansplantation The team of scientists found that transplanted photoreceptor precursor cells survived and became integrated into the mouse retina--and that the tec...

Diabetes slows nerve recovery after heart transplant

... "Using positron emission tomography (PET) and the transplanted heart as a very specific model to study the regenerative capacity of the heart's sympathetic nervous system, we determined that reinnervation--or the heart's ability to develop new nerves to replace damaged ones--is slower in diabetic patients," said...

Newts which regrow their hearts

... of signals in the cells, is phosphorylated in the transplanted cells and is thus active. The Max Planck researchers in Bad Nauheim hope that better understanding of the molecular issues involved in regeneration in the newt will open up new possibilities for the repairing human patients’ damaged hearts. ...

Vaccination with embryonic stem cells prevents lung cancer in mice

... cancer in those animals that had had cancer cells transplanted into them after the vaccination or that had been e...wth in mice that were subsequently challenged with transplanted Lewis lung carcinoma, and it was between 60-90% effective in mice subsequently exposed to carcinogen...

Human stem cells delay start of Lou Gehrig's disease in rats

...esponsible for breathing, were not helped by these transplanted stem cells." The research team used so-called ...ected with dead cells. Close examination of the transplanted cells also revealed that more than 70 percent of them developed into nerve cells, and many of those ...

Researchers create genetically matched embryonic stem cells for transplantation

...or creating mouse embryonic stem cells that can be transplanted without the risk of rejection because the cells are compatible with the recipient's immune system. The findings will be published online in the journal Science on December 14. Though done in mice, the work establishes the principle of using unfertil...

New data from NIH lab confirms protocol to reverse type 1 diabetes in mice

... staining, to follow the fate of male spleen cells transplanted into female recipients. The female mice that received male donor cells consistently showed Y-chromosome-positive insulin-producing islet cells, indicating that the introduced spleen cells contribute to islet recovery. The current study also showed th...

Cancer stem cells linked to radiation resistance

...ures in the laboratory. For the second model, they transplanted the glioblastoma tissue into the frontal lobes of the brains of mice. The researchers first measured the number of glioma stem cells present in the original tissue and then administered set doses of ionizing radiation to the cell cultures and to t...

MIT creates 3-D scaffold for growing stem cells

...to injury or disease. The scaffold itself can be transplanted directly into the body with no ill effects. "The time has come to move on from two-dimensional dishes to culture systems that better represent the natural context of cells in tissues and organs," said Zhang, whose coauthors on the paper, in additio...

A transplant in time

...ers of his lab have been experimenting with tissue transplanted from pig embryos ?a possible substitute for human ...on at 42 days. Hemophiliac mice with spleen tissue transplanted from pig embryos at this time experienced completely normal blood clotting within a month or two of ...

Stem cell expansion

...of HSCs present in a unit of cord blood means that transplanted cells can be slow to establish themselves (or engraft) in an adult recipient, prolonging the time the patient is susceptible to infections. Consequently, researchers are looking for ways to expand HSCs prior to transplantation. HOXB4 is known to be i...

Major cancer study aims to identify protein markers for early-stage disease

... will study blood samples from mice that have been transplanted with human breast cancer cells. Later they will study blood samples from patients with various stages of the actual disease. The researchers will focus specifically on a phase in protein development known as "post-translational modifications," whic...

Researchers report technique for freezing and preserving genetically enhanced pig embryos

...f altered embryos and store them until they can be transplanted to a surrogate. Swine embryos have been difficult to freeze and preserve because of their sensitivity to cold due to a high level of lipids in the cells of the embryos. It was expected that it would be even more difficult to freeze and preserve swin...

OHSU study says stem cell 'fusion' occurs in tumors

...ientists in the OHSU School of Medicine found that transplanted cells derived from adult bone marrow can fuse with...ment." In the PNAS study, Wong and her colleagues transplanted bone marrow cells from female mice into a male mouse model of intestinal cancer. The donor-derived c...

Birds going extinct faster due to human activities

...environments to grow specialized cells that can be transplanted into patients to treat epilepsy, Parkinson's, Hunt...t stem cells are taken from patients, cultured and transplanted into damaged brain environments to restore functions lost to disease or injury. "We largely keep ...

Medium is the message for stem cells in search of identities

...environments to grow specialized cells that can be transplanted into patients to treat epilepsy, Parkinson's, Hunt...t stem cells are taken from patients, cultured and transplanted into damaged brain environments to restore functions lost to disease or injury. "We largely keep ...

Bone marrow may restore cells lost in vision diseases

...ll types in the body. In this case, the cells were transplanted to confirm that bone marrow does regenerate the injured RPE. It was easier to track male, pigment-producing cells in female, albino recipients, Harris said. Chemical and microscopic analysis showed the cells that traveled to the injury site and tran...

Sperm created in the laboratory from embryonic stem cells produce viable progeny

...ed into mature sperm in the laboratory or could be transplanted into the testes of mice where they retained the ca...he resulting early stage embryos were successfully transplanted into mice. Six of the seven mice born developed into adult mice. The results of this study establi...

Stem cells found in adult skin can be transplanted and function in mouse models of disease

...dult skin can create neural cell types that can be transplanted into and function in mouse models of disease. This...ed to make bona fide neural cell types that can be transplanted into and function in animal models of disease." Other members of the research team included Drs. Ia...

Unique dual target specificity of kinase inhibitor key for success against cancer

...ity and was highly effective against human gliomas transplanted into mice. "These data suggest that combinatorial inhibition of mTOR and p110á represents a safe and effective therapy in the treatment of cancers driven by aberrant signaling through PI3 kinase," says Dr. Weiss. "Glioma represents the most common ...

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