transplanted 2 1

Tag: "transplanted" at biology news

Research shows cord blood comparable to matched bone marrow

...andards in relation to cell dose (or volume of the transplanted cells) and Human Leukocyte Antigen (HLA) diversity. Human Leukocyte Antigens (HLA) are a group of proteins on bone marrow cells that can provoke the immune system to respond. When doing bone marrow or cord blood transplants, doctors generally try ...

Human stem cell treatment restores motor function in paralyzed rats

...control group, and showed a consistent presence of transplanted cells in the spinal area. In all the rats grafted with the stem cells, the majority of transplanted human spinal stem cells survived and became mature neurons, according to Marsala. A second study was...

Machine preservation may promote more organ sharing

...donor organs, once considered unsuitable, could be transplanted safely. The category includes kidneys from deceased donors over age 60 years or those over age 50 with health conditions such as high blood pressure, stroke or elevated levels of a protein called creatinine. Levels of creatinine, which is produced by...

Students invent protective pouch to enhance cell therapy

...ve cell therapy for diabetes patients by anchoring transplanted insulin-producing cells inside a major blood vessel. A team of five seniors and two freshmen, working with Johns Hopkins doctors and engineers, devised a protective "pouch" that should fit inside the portal vein, which feeds into the liver. This po...

Dealing deadly cancers a knockout punch

...er Research Annual Meeting in April, 2007. In mice transplanted with a human colon cancer, Reolysin plus gemcitabine completely eradicated the tumors in four of five test animals. It is rare to see the virtual elimination of tumours as well as the long-lasting therapeutic effect that was observed in this study. ...

Remote sheep population resists genetic drift

... of generations from a single male and female pair transplanted to Haute Island from a Parisian zoo, has maintained the genetic diversity of its founding parents. This finding challenges the widely accepted theory of genetic drift, which states the genetic diversity of an inbred population will decrease over time...

Stem cells act through multiple mechanisms to benefit mice with neurodegenerative disease

...brain tissue destroyed by the disease. Some of the transplanted cells replaced damaged nerve cells and transmitted...ically and functionally into a diseased brain. The transplanted cells also boosted the brain's supply of the enzyme Hex, which reduced the lipid accumulations in th...

Early-stage sperm cells created from human bone marrow

...nial cells from mouse bone marrow. The cells were transplanted into mouse testes and were observed to undergo early meiosis - cell division - the next stage to them becoming mature sperm cells, although they did not develop further. Talking about his newly published research paper, Prof Nayernia, of Newcastle...

Researchers first to map gene that regulates adult stem cell growth

...ntain enough stem cells for an amount needed to be transplanted into an adult. The only stem cell population that has been examined for effects of Latexin to date is in bone marrow. Van Zant said it is possible, even probable, that other stem cell populations in tissues such as the liver, skin, pancreas or brai...

Penn researchers replace organ in adult mice using 'single-parent' stem cells

...s group found no evidence of disease linked to the transplanted cells. In another finding critical for any clinical approach using embryonic stem cells, the researchers were able to reproduce much of their findings by producing blood stem cells from embryonic stem cells entirely in the culture dish before tran...

Conceptualizing a cyborg

...wed that these stretch-grown axons could grow when transplanted into a rat model of spinal-cord damage. The team is now is the midst of studies measuring neuronal electrical activity across newly engineered nerve bridges and the restoration of motor activity in experimental animals. ...

Liposuctioned fat stem cells to repair bodies

...e University of Bologna, Italy has high hopes that transplanted fat stem cells will restore injured sports horses to their former glory. "Our aim is to regenerate the tendon structure that does not repair spontaneously," says Galli. Once scar tissue is formed, it hinders the animal’s recovery. "If you intervene,...

Linheng Li Lab documents the development of cancer stem cells

...em cells and shown that they may cause tumors when transplanted into a secondary host. Until now, however, little was known about the process by which mutations in a stem cell result in primary tumor initiation. The Li Lab team studied the intestinal system in mice in which one of the human tumor suppressor ...

Protein may hold key to decreasing organ dysfunction rates in heart transplants

...th many transplantations is the damage done to the transplanted heart during and immediately following surgery, kn...eleases enzymes and other proteins that attack the transplanted tissue, and can seriously impair the viability of replacement organs and jeopardize the health of th...

Cancer scientists create 'human' leukemia process to map how disease begins, progresses

...an" leukemia stem cells. The converted cells, when transplanted into special mice that permit the growth of human ...leukemia was grown for longer times in a series of transplanted mice. Our findings of how these leukemic stem cells functioned could explain several features of the...

MIT bioengineer advances survival, promise of adult stem cells

...ne day, stem cells removed from a patient could be transplanted to an injury site and induced to grow into new, healthy tissue. The research appears in the January 18 online issue of Stem Cells. Griffith's team focused on the potential for mesenchymal stem cells to grow into new bone in patients with bone canc...

White blood cells of cancer-resistant mice overwhelm natural defenses of cancer cells

... the same ability to attack a range of tumors when transplanted to ordinary mice. Cui and Willingham also want to explore how this one process can detect a wide range of cancer cells of so many different types. The dogma of cancer fighters has always postulated that there are many different cancers. "This new ...

Encouraging results in pancreatic cancer research

...itoneal cavities of mice containing simultaneously transplanted tumors, PNC-28 caused complete destruction of these tumors. When delivered concurrently with tumor implantation, PNC-28 completely blocked tumor growth during the two-week period of administration and two weeks post-treatment, followed by weak tum...

Proteins may predict lung transplant rejection

...predict which patients are beginning to reject the transplanted organ, they could try to head it off, she said. The study, "Proteomic biomarkers of chronic lung allograft rejection," was carried out by Wendt, Tereza Cervenka, Madelaine Haddican, Yan Zhang and Gary Nelsestuen, of the University of Minnesota, Mi...

Transplanted brain cells hold promise for Parkinson's disease

...esearchers found endogenous dopaminergic cells and transplanted neural stem cells had both survived. Also, transplanted neural cells had formed synapses to communicate with each other and ultimately the striatum, the por...

1 2 3 4 5 6