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Tag: "transplant" at biology news

Emory Study Tests Bone Marrow Stem Cells to Improve Circulation in Legs

...m cells; andin patients who have had a bone marrow transplant to increase thenumber of white blood cells. It is still considered experimental,however, for use to increase the level of EPCs in patients withperipheral vascular disease.The investigators are seeking patients in whom prior treatments,including surge...

Current human embryonic stem cell lines contaminated UCSD/Salk team finds

...eally, onlyever exposed to serum from the intended transplant recipient.""However, such an approach could not be pursued under existing rulesfor the use of federal grant dollars," Varki said.The first author of the Nature Medicine study is Maria J. Martin,Ph.D., a post doctoral researcher in Varki's lab at UCSD...

Genetically modified natural killer immune cells attack, kill leukemia cells

...n. In this case, NK cells will be derived from the transplant donor, expanded and genetically modified. These mo...ls will then be infused into the patient after the transplant in order to eliminate residual leukemic cells. In another application, NK cells could be obtained fr...

Researchers add new tool to tumor-treatment arsenal

...he immunosuppressive drug rapamycin. Used in organ transplant patients, rapamycin and its derivatives have shown promising anti-tumor activity in phase I and II clinical trials. RAD001 lowers the amount of DNA-damaging agent needed by blocking p53's DNA-repair function, automatically killing the cancer cells w...

Potential Cure for Lymphoma in HIV patients

...ing HIV infection did not worsenas a result of the transplant and associated treatments.“The results of this stu... individuals. It’simportant to know that stem cell transplant is an available and highlysuccessful treatment option for these patients,?said Amrita Krishnan,M.D.,...

Circles Of DNA Might Help Predict Success Of Stem Cell Transplantation

...physicians predict whether a bone marrow stem cell transplant will successfully restore a population of infectio...ysicians predict whether children receiving such a transplant will experience either failure or significant delay in the reconstitution of the T cell population. ...

World-first Living Donor Islet Cell Transplant A Success; Procedure Offers Promise For Diabetics

... Japan, where he originally did living donor liver transplant training with Dr. Tanaka. Dr. Masumoto was previou...uggested the idea of starting a living donor islet transplant program in Kyoto while lecturing there three years ago. Cadaveric organ donors are scarce in Japan, ...

Norovirus, AIDS vaccine and Hepatitis Virus

... in some cases can cause liver failure requiring a transplant for survival. The protein interferon, produced by animal cells when they are invaded by viruses, is released into the bloodstream or intercellular fluid to induce healthy cells to manufacture an enzyme that counters the infection. One class of interf...

Epstein-Barr virus protein crucial to its role in blood cancers

...in cancers such as lymphoproliferative diseases in transplant or AIDS patients, Burkitt's lymphoma, Hodgkin's ly... studies will be in lymphoproliferative disease in transplant and immunocompromised patients because this is a clear case of EBV-driven B-cell lymphoma. The use ...

Defensins neutralize anthrax toxin

...in cancers such as lymphoproliferative diseases in transplant or AIDS patients, Burkitt's lymphoma, Hodgkin's ly... studies will be in lymphoproliferative disease in transplant and immunocompromised patients because this is a clear case of EBV-driven B-cell lymphoma. The use ...

Viral protein influences key cell-signaling pathway

...current study used a non-infectious form of HIV to transplant the HTLV-1 p12 gene into laboratory-grown T cells. The infected cells then produced a constant level of p12 protein. The researchers then used gene microarray technology to identify which cellular genes out of 33,000 become either more or less active...

Light therapy may combat fungal infections, new evidence suggests

...ho lack a functioning immune system, such as organ transplant recipients, those with HIV/AIDS, and patients treated with steroids or cancer chemotherapy. The fungus' global importance as a health threat has therefore risen in parallel with the increase in immunosuppressive therapies and the worldwide HIV/AIDS e...

Gene therapy promising for growing tooth-supporting bone

...py outside the body using a tissue biopsy and then transplant the genetically-modified cells back into the patient, but this would require two surgical procedures instead of one. The Molecular Therapy paper is titled "BMP Gene Delivery for Alveolar Bone Engineering at Dental Implant Defects," and the work was ...

Rare surgery performed to remove pancreas, prevent diabetes

...lantation, and directs the University's islet cell transplant program, which uses pancreatic cells from brain-de...t diabetics. Contreras is co-director of the islet transplant program. The patient was in intensive care at UAB Hospital for two days following the surgery, and w...

Infants With Rare Genetic Disease Saved by Cord Blood Stem Cells

...England Journal of Medicine. Without an immediate transplant of stem cells, Krabbe infants rapidly begin to los...Blood and Marrow Transplant Program. "Delaying the transplant even a week or two can make a noticeable difference in a child's motor skills, so timely diagnosis a...

Genetically Modified Natural Killer Immune Cells Attack, Kill Leukemia Cells

...n. In this case, NK cells will be derived from the transplant donor, expanded and genetically modified. These mo...ls will then be infused into the patient after the transplant in order to eliminate residual leukemic cells. In another application, NK cells could be obtained fr...

Same-Sex Mating Discovered in a Toxic Fungus

...monly in immune-compromised patients such as organ transplant recipients and cancer patients -- whose immune systems are crippled by immunosuppressive drugs or chemotherapy -- and people with HIV/AIDS. The fungus' global importance as a health threat has therefore risen in parallel with the increased use of suc...

MUHC scientists describe genetic resistance to rampant virus

...he life of HIV patients and improve the success of transplant surgery by reducing the risk of rejection. There i...se with a compromised immune system, such as organ transplant recipients, newborns and persons infected with human immunodeficiency virus (HIV). Dr. Vidal believe...

Scientists discover that three overlapping signals in embryo help get the backbone right

... Khokha said. "If you cut out a similar tissue and transplant it in a mouse, you also get the Siamese twin phenomenon. So, we expect it to also be true in humans." ...

Infants with Rare Genetic Disease Saved By Cord Blood Stem Cells

...England Journal of Medicine. Without an immediate transplant of stem cells, Krabbe infants rapidly begin to los...Blood and Marrow Transplant Program. "Delaying the transplant even a week or two can make a noticeable difference in a child's motor skills, so timely diagnosis a...

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