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Tag: "translate" at biology news

Georgia Tech accelerates drug discovery with new IBM supercomputing cluster

...ent systems to help their intellectual communities translate the research they generate into viable information for the commercial market," said Doug Balog, vice president, IBM BladeCenter. "With the Cluster 1350 system based on the AMD Opteron LS20 IBM BladeCenter, students and faculty of Georgia Tech are gai...

Component in soy products causes reproductive problems in laboratory mice

...ertain about how these animal studies on genistein translate to the human population, there is some reason to be cautious," said Dr. David A. Schwartz, Director of the National Institute of Environmental Health Sciences (NIEHS). "More clinical studies are needed to determine how exposure during critical windo...

Loosen leash on cancer protein 'watchdog,' researchers say

...ould need to be answered before the research could translate into human therapy. "These mice were genetically modified at conception to produce higher p53 levels, which is quite a different treatment than just giving normal mice a pill," Mendrysa said. "Also, mice in our study are not subject to the same stre...

Data published in PNAS show antibodies can be made 10 times more toxic to cancer cells

...ave optimized antibody-Fc receptor affinity, which translate into increased effector functions and improved cell cytotoxicity. These can be used to enhance the potency of nearly any antibody under development today," Dahiyat added. ...

Stem cell transplants improve recovery in animal models for stroke, cerebral palsy

...San Diego. In humans, the findings hopefully will translate to incremental but important recovery advances, said Dr. David Hess, adult stroke specialist, chair of the MCG Department of Neurology and a study co-author. "The single largest cause of disability among adults in ths U.S. is stroke," said Dr. Hess....

Predicting successful outcomes in living-donor liver transplants

...s of function compared to preoperative values will translate into clinically relevant impairment of liver function ?in particular with respect to drug metabolism as suggested by the authors ?has yet to be determined," he states. He also notes that the multiple blood sampling used by the second study is quite l...

Marrow-derived stem cells deliver new cytokine to kill brain tumor cells, offer protection

...archers are now applying to regulatory agencies to translate their work into human clinical trials. Gliomas are highly invasive tumors with poorly defined borders that intermingle with healthy brain tissue, making complete surgical removal nearly impossible. Furthermore, cells separate from the main tumor and...

Flick of a protein switches immune response

...ctors" acting on it. Transcription factors help to translate a gene's instructions into actual proteins. FOXP3 and NFAT are two such factors; the human body contains around 3,000. "The work provides a structural demonstration of combinatorial control of gene expression," Chen said. "This is, in my view, the ...

UF scientists discover evolutionary origin of fins, limbs

... have evolved in the first place," Burke said. "To translate a 19th century observation about fin development into modern molecular data is a great thing for science. It has become increasingly important to understand developmental processes in our attempts to understand evolution." ...

Bubbles go high-tech to fight tumors

...t topics that must first be understood in order to translate this developmental technique to the clinic. In traditional embolotherapy techniques, the so-called cork that doctors use to block the blood flow---called an emboli---is solid. For instance, it could be a blood clot or a gel of some kind. A major di...

When the going gets tough, slime molds start synthesizing

...g various computer programs to find, assemble, and translate in silico the relevant raw DNA sequencing fragments first into genes then into the proteins these genes encode, Austin reconstructed two type III PKS-like gene sequences, and also found a surprise. Unexpectedly, these deduced genetic blueprints for...

How healthy is that marsh? Biologists count parasites

...ils, identify the trematodes inside them, and then translate this information into information on resident populations of birds, fishes and benthic invertebrates. "We think counting trematodes is an effective tool for assessing the biodiversity of salt marshes in California," Lafferty said. "We are interested...

Even a little cooling helps after cardiac arrest

...ils, identify the trematodes inside them, and then translate this information into information on resident populations of birds, fishes and benthic invertebrates. "We think counting trematodes is an effective tool for assessing the biodiversity of salt marshes in California," Lafferty said. "We are interested...

Tumor wizardry wards off attacks from the immune system

...acking the problem from different angles hoping to translate these findings to our patients," Linehan says. "Right now, no effective treatment exists for pancreatic cancer." ...

Brain-computer link lets paralyzed patients convert thoughts into actions

...y of Chicago -- the task of creating algorithms to translate the chatter between neurons in the motor cortex into a language the computer could understand and use to control other devices. Hatsopoulos and other students in the Donoghue lab were slowly able to match neuronal signal patterns with specific arm mo...

Large-scale genomics project will hunt genes behind common childhood diseases

... genes. The Center's researchers will then work to translate the genetic knowledge into precisely targeted treatments for the diseases in question, customizing treatments to a child's genetic profile. "We are following a trail blazed by the Human Genome and HapMap Projects, but tailoring our approach to child...

A rice future for Asia

...re," Dr. Gomez added. "The challenge is to try and translate this into a sense of excitement and interest amongst young people in Thailand and all over Asia." ...

New technology enables faster, more efficient cell harvest: Cell therapy meeting study

...esident, Pall New Technologies. "Pall was able to translate its material science expertise on the interactions between media and cells based on our long-standing leadership in blood filtration to develop this new approach to cell harvesting." The Pall system can be used to harvest cells from a broad range of...

Embryos exposed in 3-D

...esident, Pall New Technologies. "Pall was able to translate its material science expertise on the interactions between media and cells based on our long-standing leadership in blood filtration to develop this new approach to cell harvesting." The Pall system can be used to harvest cells from a broad range of...

The brain's motivation station

...ory activation of this mesolimbic circuit may help translate motivation into memory." ...

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