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Tag: "transformation" at biology news

Recent breakthroughs in common adult leukemia highlighted in New England Journal of Medicine

...CLL) to write an authoritative update covering the transformation in the scientific community's knowledge of CLL that has occurred over the past decade. The review appears in the February 24 issue. Two of the expert authors are with the North Shore-Long Island Jewish (LIJ) Health System (www.northshorelij.com): Ni...

Gene therapy converts dead bone graft to new, living tissue

... into the body's own, whole, living bone." Such a transformation can occur because mammals use their skeletons for both support and as a kind of "calcium bank." If calcium, which is necessary for such important functions as maintaining the brain and heart, runs low, cells called osteoclasts dig out the calcium fro...

Tiny scaffolding allows stem cells to become working fat cells

...s called pre-adipocytes cells that had begun their transformation from stem cells. "They just needed to be tweaked w...lve into fat cells," he said. Kniss said that the transformation into bona fide fat cells took about two weeks to complete. At that point, the cells were able to abs...

Technique may allow cancer patients to freeze eggs, preserving fertility before starting treatment

... allows the eggs to be cooled fast enough that the transformation from liquid to solid is instantaneous. No ice crystals form and the consistency resembles a viscous glassy state. Research so far has used mouse oocytes but U-M expects to make the technology available in the clinic soon. "With traditional slow-free...

Compounds in plastic packaging act as environmental estrogens altering breast genes

...aboratory has pioneered an in vitro system of cell transformation using estrogens and their metabolites as carcinogenic agents in human breast cells. Our data show that each compartment of the breast has specific differentially expressed genes that provide a genomic signature according to the increasing maturation ...

Could microbes solve Russia's chemical weapons conundrum?

...rs conclude that the 1,4-perhydrothiazines undergo transformation by the microbial cells when a growth substrate (MEA/EG) is present. However as the cells did not grow in the presence of PHT alone, the authors conclude that the bacteria cannot use them for growth. The group hopes that the bacterial strain can be u...

Amazon symposium to address large-scale conservation

...sion along emerging highway corridors, and (3) the transformation of grain and beef production industries into proponents of Amazon conservation using a combination of market-based instruments and improved government regulation. This symposium will provide a state-of-the-art assessment of the processes that are th...

Best research work in the area of wine growing

...umption, that determine the quality of production, transformation and commercialisation of horticultural products. Response to hydric stress The communiqué from the researchers at the Public University of Navarra dealt with the theme of the response of a determined species or variety to the hydric stress. A respo...

Immune system's distress signal tells bacteria when to strike back

...npoint key early steps of this lethal process. The transformation starts when a weakened host tries to boost its defenses against any possible invasion. The host's T cells release chemical signals that activate the immune system. One of those signals, interferon-gamma, is intercepted by a protein, called OprF, foun...

Woods Hole Research Center plans controlled burn in Amazon rainforest

Fire is an important agent of transformation in the Amazon landscape. Every year, low intensity fires burn thousands of square miles of Amazon forest. To study the effects of these fires on the forest, and the forests' ability to recover from repeated burning, Woods Hole Research Center scienti...

Engineered skin offers clues to melanoma development

... form of skin cancer, resulting from the malignant transformation of cells called melanocytes. Over the past four de...the importance of moving away from simplified cell transformation studies to studies of functional human tissue," Chudnovsky said. "Skin is easily accessible and can ...

Ibruprofen and other commonly used painkillers for treating inflammation may increase the risk of heart attack

... form of skin cancer, resulting from the malignant transformation of cells called melanocytes. Over the past four de...the importance of moving away from simplified cell transformation studies to studies of functional human tissue," Chudnovsky said. "Skin is easily accessible and can ...

Researchers use RNAi libraries to identify regulators of apoptosis and chemoresistance

... form of skin cancer, resulting from the malignant transformation of cells called melanocytes. Over the past four de...the importance of moving away from simplified cell transformation studies to studies of functional human tissue," Chudnovsky said. "Skin is easily accessible and can ...

Scientists find a maturity gene in fly

...juveniles begin to mature into adults, and how the transformation initially proceeds. Understanding this process in ...e because insect metamorphosis is analogous to the transformation of a human "from a juvenile, non-reproductive stage to a mature, sexually reproductive adult," says ...

MWG Biotech expands siMAX?siRNA portfolio with new scales, lengths and design tools

...juveniles begin to mature into adults, and how the transformation initially proceeds. Understanding this process in ...e because insect metamorphosis is analogous to the transformation of a human "from a juvenile, non-reproductive stage to a mature, sexually reproductive adult," says ...

Scientists unpick genetics of first 15 minutes of life

...ity of Bath. "Sperm DNA has to undergo a complete transformation when it arrives in the egg cell so that it can properly join with the female pronucleus to form a new genetically complete the beginning of a new life. "A slight mutation in the HIRA gene means that life does not even get started. "Amazingly we sti...

Sudden change in social status triggers genetic response in male fish, study finds

... ("eyebar") appears across his face. This physical transformation signals to males and females alike that he's the t... colleagues were the first to observe this diurnal transformation among dominants. "During the experiment, I would remove the dominant male one hour before the ligh...

Model identifies genes that induce normal skin cells to become abnormal

...nfluence of the tumor cell microenvironment on the transformation of normal skin cells, as well as on genetic triggering mechanisms and signaling pathways that could be targeted for novel therapeutic strategies to inhibit the spread of melanoma," Hendrix said. Metastatic cancer cells are characterized by increased...

Why the Amazon rainforest is so rich in species

...t at very different rates, and their extinction or transformation is mostly determined by the ecology and biology of each species. We want to discover more about why some species survive and multiply, while others remain static or become extinct." Around 40% of the world's species can be found in the tropical area...

Source of crucial immune cell in the skin discovered

... and identified a protein that is essential to the transformation of these precursor cells into Langerhans cells. T...ating factor receptor (Csf-1) is necessary for the transformation of Gr-1 cells into Langerhans cells. The researchers state that discovery of how Langerhans cells a...

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