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Tag: "transcribing" at biology news

Novel Enzyme Shows Potential As An Anti-HIV Target

...cally modifies the RNA polymerase and enhances its transcribing efficiency. The transcription process—including the labyrinthine protein–protein and protein–DNA (and in the case of Tat, protein–RNA) interactions—is highly regulated. One process that figures prominently in this regulation is acetylation, which ad...

An HIV Protein Plays a Surprising Role in Gene Activation

... three types of RNA polymerases, each charged with transcribing different types of genetic elements. RNA polymeras...to the HIV promoter, and enhances RNA polymerase's transcribing capacity. Previous studies in yeast had shown that activators appear to stimulate transcription comp...

Discovering the first steps in transcription-coupled repair

...ncounters a damaged nucleotide on the strand it is transcribing -- the sort of damage that might have been inflicted by ultraviolet radiation or oxidative damage, for example. Or it may encounter situations such as a highly repetitive sequence of bases, with folding of the DNA upon itself, which make progress dif...

When it comes to gene transcription, random pauses aren’t quite so random, study finds

...itous pauses") when carrying out the vital task of transcribing genetic information from DNA to RNA--a process called transcription. "Transcription of genes is terribly important," said study co-author Steven M. Block, professor of biological sciences and of applied physics at Stanford. "It's what determines th...

From a lowly yeast, researchers divine a clue to human disease

...ther protein called RNA polymerase II when to stop transcribing genetic information from DNA into related threads of RNA. The polymerase reads along DNA strands, building RNA as it goes. Multiple genes strung along a single length of DNA are separated by gaps to mark boundaries. As the polymerase reaches the e...

Nobel Laureate finds 'elegant' explanation for DNA transcribing enzyme's high fidelity

...up captured the first picture of the polymerase II transcribing complex by X-ray crystallography in 2001. Those st... transcript. Later X-ray structures revealed the transcribing complex with the addition site available for entry of a matched NTP. Those crystals uncovered a seco...

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