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Tag: "toxic" at biology news

Agent slows aging in mice

...ng that is harmless in mice turns out to be highly toxic for people,” Miller cautions, adding that the Food and Drug Administration doesn’t evaluate the safety of such herbal remedies....

Cells re-energize to come back from the brink of death

...lly targeted drug might be more effective and less toxic than standard chemotherapy. A report on this work is in the June 1 issue of “Cell.” Apoptosis is triggered by a variety of factors, including gene mutations that can make the cell become cancerous. During apoptosis, the membrane covering the cell’...

Researchers track how spores break out of dormant state

...nvironmental factors including heat, radiation and toxic chemicals. However, once in favorable conditions, spores break the dormant state through germination and reenter the vegetative mode of replication. Although significant progress has been made in understanding the biochemical and genetic bases of ...

Largest synthetic gene ever built offers insights into anti-malarial drug resistance

...grades the hemoglobin in the red cell, producing a toxic byproduct known as heme, which the parasite then c...zation, which destroys the parasite by building up toxic levels of non crystalline heme. But because of the overuse of chloroquine, isolates of P. falcipa...

Pesticides choke pathway for nature to produce nitrogen for crops

... used in the research, including PCP, proved to be toxic to either the plants or bacteria, Fox said, "but PCP was unique in that it inhibited both seed germination and nitrogen fixation." More than 20 commonly used agricultural chemicals shared the same mechanism of action as PCP, but with varying amounts ...

Newly found sensing system enables certain bacteria to resist human immune defenses

...hat can lead to food poisoning, skin disorders and toxic shock—avoid being killed by AMPs. AMPs are made by virtually all groups of organisms, including amphibians, insects, several invertebrates and mammals, including humans. “Gram-positive bacteria are major threats to human health, especially due to ...

U-M researchers discover gene switched off in cancer can be turned on

...hanged in 30 years. Newer treatments are much less toxic and extend lives by months, but the same people wh...t and progress of cancers. They typically have few toxic side effects, unlike traditional chemotherapy, making them more tolerable as a long-term treatment o...

Researchers examine carbon capture and storage to combat global warming

...increase the water's acidity, potentially leaching toxic chemicals, such as lead, from rocks into the water, she said. To address these risks, scientists are studying reservoir geology to better understand what happens after injecting carbon dioxide underground. ''You need to carefully select places ...

Newly discovered antibody may be body's natural defense against Alzheimer's

... beta amyloid proteins called "oligomers" that are toxic to brain cells, while ignoring the benign single-m...e that proteins assume only when they become these toxic aggregates." The ability of the antibodies to recognize toxic proteins based on their shape may ...

Microbes at work cleaning up the environment

...g just that to protect themselves from potentially toxic nanoparticles in their own environments, and clean...he nanoparticles themselves, which are potentially toxic to the bacteria. Sulfate-reducing bacteria can cause heavy metals such as zinc (Zn) to precipita...

Penn researchers link cell's protein recycling systems

...neurodegenerative diseases because accumulation of toxic proteins is a common underlying feature of age-related neurodegeneration.” Taylor and his group study fruit flies in which the proteasome is disabled by a genetic mutation, which results in neurodegeneration. They use the fly eye, a neuron-rich t...

Helping chlorine-eating bacteria clean up toxic waste

...nd then to make them more effective in cleaning up toxic wastes. Bacteria called Dehalococcoides ethenogenes, discovered in Ithaca sewage sludge in 1997 by James Gossett, Cornell professor of civil and environmental engineering, and isolated and studied by Stephen Zinder, Cornell professor of microbiology...

Common treatment for methamphetamine overdose may damage brain cells

...of cells by the amino acid glutamate, which proves toxic to cells producing the neurotransmitter gamma-aminobutyric acid (GABA). Their results are published in the May 30 issue of The Journal of Neuroscience . "This work in laboratory animals raises immediate concerns that a standard treatment for meth...

For many insects, winter survival is in the genes

...ature as well as during exposure to high levels of toxic chemicals, dehydration and even desiccation," Denlinger said. He and his colleagues first figured out how many genes were turned on only during the flesh fly's dormant state. The researchers extracted and compared RNA from both dormant and non-dor...

An 'elegant' idea proves its worth 25 years later

...l "waste disposal" chemistry to mop up potentially toxic nitrogen has saved an estimated 80 percent of pati...the body carries more nitrogen out and reduces the toxic effects of excess nitrogen accumulation." Excess nitrogen yields ammonia, which is poisonous and ...

A cherry on top: Tart cherries may alter heart/diabetes factors

...s. The higher cherry dose was used to look for any toxic effects; none were seen. The cherries were Montmorency tart cherries grown in northern Michigan, frozen, and powdered. Michigan is the nation's largest producer of tart cherries, which are used in pies and jams as well as juice. They are differen...

pHLIP, a novel technology to locate and treat tumors

... “The transported molecules can be therapeutic or toxic to the cell, depending on the intended outcome—for treating cancer, the idea is to cause cell death.? In addition to targeting tumors, other disease states that produce inflammation and cause tissue to be acidic are a target for pHLIP. “Acidosis i...

Cancer patients monitor fatigue in real time

... to the bone marrow, causing anemia and by forming toxic substances in the body that interfere with normal cell functions. "People who are having problems breathing -- another symptom of some cancers -- may also experience fatigue." According to Hacker, this is the first study of real-time collection...

Maggots rid patients of MRSA

...tment in contrast to the expensive and potentially toxic antibiotic remedies." ...

Molecule that destroys bone also protects it, new research shows

... mechanism." Gaffen said IL-17 likely would be toxic if given systemically, so it may not be a therapeutic candidate to increase immunity. But inhibitors of IL-17 are considered important targets for drugs to treat autoimmune diseases such as RA and psoriasis. On the down side, however, this new fi...

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