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Tag: "topical" at biology news

Maggots rid patients of MRSA

...h pressure relieving dressings to protect them. No topical antimicrobial agents or growth factors were used on the study ulcer. All but one of the patients was cleared of the superbug. During the treatment period, no adverse reactions were reported and there was a reduction in sloughy necrotic tissue and ...

Synthetic peptide targets latent papilloma virus infections

...enter cells easily, the peptide has potential as a topical treatment for the viral infection. "We didn't start out looking for a way to develop a drug, but we stumbled across a way to get the peptide taken up by the cell, and it works," said Voitenleitner. "So far, though, we've only shown that it has a sh...

Long-term narcotics use for back pain may be ineffective and lead to abuse

...earch focused on efficacy of oral, transdermal, or topical opioids, where there was no pre-existing diagnosis of opioid dependence. According to the report, opioids may be effective for the short-term (less than four months) treatment of chronic low back pain, but long-term effectiveness was not conclusiv...

Active ingredient in common Chinese herb shown to reduce hypertension

...pression of endothelial nitric oxide synthase. The topical application of tanshinone IIA at one ¦Ìg/ml and five ¦Ìg/ml caused significant dose-related vasodilation, indicated by the increased agent/control ratio of arteriolar diameters from 1.0 to 1.25¡À0.08 and 1.57¡À0.11, respectively, in the hamster cheek...

Chemicals in brown algae may protect against skin cancer

....7 and 3.7 tumors respectively. Of those given the topical treatment, the lower and higher doses developed 3....n animals exposed to UVB alone. Of those given the topical treatment, the lower and higher dose animals had tumors that were 27 percent to 43 percent smaller t...

From managing sugar to managing healing

...en and colleagues explored the molecular impact of topical insulin on keratinocytes, the cells that regenerate the epidermis after wounding, and on microvascular endothelial cells, the cells that restore blood flow. Using various cell and molecular techniques, the researchers discovered that insulin stimu...

Study defines effective microbicide design for HIV/AIDS prevention

...mputer tool they say could lead to improvements in topical microbicides being developed for women to use to p...the lining of a woman's vagina after she applies a topical microbicide. The model describes the diffusion of the virus and active ingredients into the tissues,...

Science finds new fix for UV-damaged skin in arthritis treatment

...citing to see this level of research being done on topical cosmetic applications of glucosamine, and the prom...Kimball. "The level of research and validation on topical cosmetic application of glucosamine will help it stand apart from other ingredients when it comes to...

Polymer aids in blood clotting, pointing way to new treatment

...ll test the use of polyphosphate as an additive to topical agents as well as new nanotechnologies in an animal model to develop effective treatments for situations involving uncontrollable bleeding. Such scenarios, Morrissey said, could include treatment for wounds sustained on battlefields or in accidents,...

Anti-HIV drug has potential to prevent transmission in women

...ive use, the paper states. "A safe and effective topical microbicide would offer women an HIV prevention method that they could control," Mayer says. In addition, researchers evaluated a subgroup of women in the study to determine if the active ingredient in tenofovir gel was absorbed into their bloodstr...

Protein finding could lead to treatment for inflammatory diseases

...mune system may become the key ingredient in a new topical treatment for inflammatory diseases, say medical r...ions. Doing so would simplify the preparation of a topical treatment that would inhibit painful inflammatory responses. The molluscum contagiosum virus that p...

Needle-free immunizations

...y available methods of immunization, which include topical application to the skin, pills, nasal sprays, injections, and others. Considerable advances have been made in the past decade, especially in transdermal (through the skin) and nasal immunization. "Unfortunately, because of the development costs of n...

'Creationism is not science' ?making the case for Darwin at UCL

...m of Zoology at UCL, has a tradition of addressing topical scientific issues. The museum was renamed nine yea...ould. This year's lecture promises to be just as topical as the first. Dr Helen Chatterjee, Curator of the Grant Museum of Zoology at UCL, said: "This lectur...

Old drug shows new promise for Huntington's Disease

... in the United States in 1971 but is still used in topical applications, appears to block the genetic action of Huntington's disease in mice and in cell culture, according to a study reported by San Francisco VA Medical Center (SFVAMC) researchers. The study, led by principal investigator Stephen M. Massa, ...

Study uncovers dirty little secret: Soil emissions are much-bigger-than-expected component of air pollution

...pected," she said. "The biggest areas were the dry topical regions like the Sahel, and in the mid-latitude regions where there is a lot of agriculture." During summer in North America, Europe and Asia, nitrogen oxides emitted from soil can reach half the emissions from fossil fuel combustion. "And this is ...

Research on antibiotics receives historical recognition

...Waksman's laboratory was neomycin, still used as a topical antibacterial agent. William F. Carroll, Ph.D., president of the Society, will present a commemorative bronze plaque to Tim Casey, Ph.D., Dean of Academic and Student Programs at Cook College, Rutgers University. H. Boyd Woodruff, Ph.D., who isolate...

MetaChip provides quick, efficient toxicity screening of potential drugs

...ety and preliminary effectiveness of two candidate topical microbicides to prevent HIV infection has opened t...on of AIDS. "It is a critical trial evaluating two topical microbicides with differing mechanisms of action," she adds. The microbicides to be tested are PRO ...

International trial of two microbicides begins

...ety and preliminary effectiveness of two candidate topical microbicides to prevent HIV infection has opened t...on of AIDS. "It is a critical trial evaluating two topical microbicides with differing mechanisms of action," she adds. The microbicides to be tested are PRO ...

Topical treatment shown to inhibit HIV and herpes simplex virus infection

...lth (NIH) investigated the efficacy of PRO 2000, a topical microbicide under development by Indevus Pharmaceuticals, Inc. "There is an urgent need for the development of safe and effective vaginal microbicides," Marla Keller, M.D., Assistant Professor of Medicine at the Mount Sinai School of Medicine and th...

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