Immune system's distress signal tells bacteria when to strike back
...s tenants' survival. Pseudomonas, however, has the tools to engineer its own escape ?by killing off the host. This wily pathogen can evade a host's immune system. It can repel antibiotics, secrete toxins similar to those used by anthrax, latch onto the bowel wall, bore its way through, and flow into the b...Protein synthesis can be controlled by light, opening way for new scientific, medical applications
... Dore. Generally speaking, there are few research tools available that are location-specific, so the new method adds a potentially powerful tool for scientists. Often, manipulations are carried out on all parts of a sample, but researchers have learned that much of biological function is dependent on the ...UI researcher studies deafness in fruit flies, humans
...the fruit fly and its love song are very effective tools for learning about the molecular and cellular mechanisms involved in hearing in insects and animals, including humans, says Eberl, who is trying to identify the genes responsible for hearing in fruit flies. Whether or not mutant fruit flies can hear...Bioinformatics reveals new gene regulation system
...nown," said Gelfand. Using multiple bioinformatics tools can uncover cell systems that might have escaped experimental detection, he suggested. "By comparing hundreds of genomes, you can see patterns that are not seen when looking at just a couple of them." ...Deep thinking: Scientists sequence a cold-loving marine microbe
... Early Edition July 25-29, reveals key biochemical tools that cold-adapted, or psychrophilic, bacteria can use to survive in subzero temperatures. In particular, some of C. psychrerythraea's estimated 4,937 genes apparently code for adaptive traits such as cell membranes packed with polyunsaturated fatty a...When it comes to cell entry, being average has its advantages
... significant for developing gene and drug delivery tools as well as assessing the safety of nanotubes ?infinitesimal bits of carbon and other materials used in everything from cameras to clothing. "If you know how viruses get into cells, you know how to better design drugs to keep them out," said L.B. Fre...Modified collagen could yield important medical applications
...edications while serving as a coating for surgical tools and implants. "With this process," Yu said, "we can make the collagen that's already found in the human body behave in new ways, including some ways that are not found in nature. Modified collagen can give us great new tool for treating injuries and...Unusual antibiotics show promise against deadly 'superbugs'
...edications while serving as a coating for surgical tools and implants. "With this process," Yu said, "we can make the collagen that's already found in the human body behave in new ways, including some ways that are not found in nature. Modified collagen can give us great new tool for treating injuries and...Enlisting genomics to understand flu evolution
...nomes scientists collect--and the more refined the tools of genomics become--the greater the chances of developing more effective vaccines. Citation: Holmes EC, Ghedin E, Miller N, Taylor J, Bao Y, et al. (2005) Whole-genome analysis of human influenza A virus reveals multiple persistent lineages and reas...Understanding biases in epidemic models important when making public health predictions
...ical models have become invaluable decision-making tools for public health officials. As demonstrated during the United Kingdom's foot-and-mouth epidemic of 2001, models can be useful in two ways: they can reveal the underlying characteristics of an infection and they can allow the comparison of alternativ...Newly discovered genetic disease sheds light on body's water balance
..."Water retention is a common problem, and with new tools we can examine our long-held assumptions about its cause," Rosenthal said. "There may be mutations in other components of the V2 receptor signaling cascade that result in inappropriate antidiuresis." In fact, after Feldman presented this work at an ...Inhaling large amounts of salt can cause hypertension
...ical models have become invaluable decision-making tools for public health officials. As demonstrated during the United Kingdom's foot-and-mouth epidemic of 2001, models can be useful in two ways: they can reveal the underlying characteristics of an infection and they can allow the comparison of alternativ...Field of beams - Novel system uses polarized light pulses to reveal crop health
...ical models have become invaluable decision-making tools for public health officials. As demonstrated during the United Kingdom's foot-and-mouth epidemic of 2001, models can be useful in two ways: they can reveal the underlying characteristics of an infection and they can allow the comparison of alternativ...Neandertal femur suggests competition with hyenas and a shift in landscape use
...ome animal bones showing both cut marks from human tools and tooth marks from hyenas. Additionally, the human femur was gnawed by carnivores, probably hyenas. This shows that close competition for food and space persisted through the Middle Paleolithic among these Neandertals. ...Study shows how retinoic acid enters a cell's nucleus
...o-carcinogen -- it promotes cancer. Armed with new tools and knowledge, she hopes to figure out how to suppress the ability of this protein to move to the nucleus and promote cancer, perhaps by blocking the hormone that switches on its NLS. In previous experiments with mice, Noy and her colleagues showed ...... response to bacteria, enabling the development of tools used to test humans, drugs, and sterile environments for toxins. Skate (Raja erinacea): Human retinas have two kinds of light-sensing cells: rods and cones. Skate retinas have only rods--yet they can still sense light. MBL scientists have studied sk...Divergent life history shapes gene expression in brains of salmon
...y difficult in the past because we lacked adequate tools to measure gene expression," Aubin-Horth says. "As a result almost nothing is known about the molecular basis of developmental plasticity such as that seen among 'sneaker' salmon." ...Deep sleep short-circuits brain's grid of connectivity
...d in the development of diagnostic and therapeutic tools for neurological and psychiatric disorders that affect consciousness, such as schizophrenia. That work is now being pursued by the Wisconsin group. In addition to Tononi and Massimini, co-authors of the Science paper include Fabio Ferrarelli, Reto H...New Discovery May Help Doctors Treat Infertility
...omen already undergoing fertility treatment. “The tools and animal models necessary to do these types of studies have only recently become available, but are already helping us to better understand the role of estrogen in the ovary,?said John Couse, Ph.D., lead author of the August paper. An earlier NIEH......d in the development of diagnostic and therapeutic tools for neurological and psychiatric disorders that affect consciousness, such as schizophrenia. That work is now being pursued by the Wisconsin group. In addition to Tononi and Massimini, co-authors of the Science paper include Fabio Ferrarelli, Reto H...