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Tag: "tool" at biology news

First 'encyclopedia' of nuclear receptors reveals organisms' focus on sex, food

...'s Cell. Dr. Mangelsdorf said the poster will be a tool for researchers engaged in advanced investigation of the biological role of each receptor individually and as a superfamily. The paper and poster also are available online as part of the Nuclear Receptor Signaling Atlas ( www.NURSA.org ), a consortiu...

Matrilin-3 gene discovered to prevent onset of osteoarthritis

...itis. Potentially, we could use it as a diagnostic tool or to predict whether someone is likely to develop osteoarthritis," says senior author Qian Chen, PhD, director of cell and molecular biology, and head of orthopaedic biology research at Rhode Island Hospital. Chen is also a professor of medical s...

Mitochondrial DNA sequencing tool updated

...authors say their full-sequence chip will be a key tool in accelerating research on mitochondrial DNA, a g...d Craniofacial Research. "The v2.0 is a very good tool in that we've also arrayed 500 of the most common haplotypes - or grouped patterns of known DNA vari...

Study finds how organs monitor themselves during early development

... says Dr. Lehmann. The experiments Using a tool called the Gal4/UAS system, the researchers overexpressed genes of interest. They honed in on a set of signaling molecules in order to interfere or augment particular signaling pathways. They looked at how the interaction between the two types of cel...

Polymers show promise for lab-on-a-chip technology

...e of liquid crystalline polymers (LCP) as a viable tool for use in devices such as the sought-after lab-on-a-chip technology. University of Alberta researchers, collaborating with colleagues at the Eindhoven University of Technology and Phillips Research Laboratories in the Netherlands, have shown that L...

Speeding discovery of the 'human cancer genome'

...ed as a filter to help reduce that noise, and as a tool to determine, in areas of chromosomal alteration, what changes are functionally relevant." The difficulty stems from the fact that studies that scan the genomes of human tumors for differences typically find hundreds to thousands of genes that dis...

Johns Hopkins lab scientists tame overactive CF protein

... transport chloride in and out of cells. Using a tool called RNA interference on cells in the laboratory, researchers successfully intercepted signals sent out by the rampant protein and prevented cell damage by the protein, effectively restoring the cell to normal. "The hope is that these findings wil...

Biomarkers may hone anti-aging therapies

...e newly identified biomarkers will provide another tool for studying mitochondrial damage that contributes to aging and cancer, and for screening compounds that prevent or reverse the process, Sligh said. ...

Marrow-derived stem cells deliver new cytokine to kill brain tumor cells, offer protection

...ne Dunitz Neurosurgical Institute have developed a tool to track and kill malignant brain tumor cells and provide long-term protection against their return. Results of an animal study are published in the March 1, 2006 issue of Cancer Research, and the researchers are now applying to regulatory agencies ...

UCR researchers design chip that can improve citrus varieties

...ilable citrus sequences to develop an entirely new tool that will benefit all citrus researchers and help sustain the citrus industry locally and worldwide," said Timothy Close , a professor of genetics at UCR and a co-leader of the project. "We owe a special thanks to colleagues in the citrus community...

MIT researchers build tiny batteries with viruses

...of inducing this order comes from self-assembly, a tool that is commonly used now in Hammond's lab. "By harnessing the electrostatic nature of the assembly process with the functional properties of the virus, we can create highly ordered composite thin films combining the function of the virus and polymer...

Research tracks whales by listening to sounds

Researchers have developed a new tool to help them study endangered whales ?autonomous hydrophones that can be deployed in the ocean to record the unique clicks, pulses and calls of different whale species. Those efforts are leading to some surprising findings, including the discovery b...

Study finds 60 new genes controlled by DNA snippet

...ate (within 4,000 base pairs). The data-screening tool also employed comparative genomics, the study of relationships between the DNA of different species. When a piece of genetic material, gene or regulatory segment, is conserved by evolution from mice to humans it suggests that the segment has a valuab...

Unraveling the viral mechanism

... as Chiu and Jiang used the computer visualization tool to strip away the surface shell entirely, they saw the concentric coil of DNA underneath. They also identified a protein "hub" through which DNA enters and exits the virus. "It's like a garden hose, in some ways," said Chiu. "You extend it. If you p...

New method enables gene disruption in destructive fungal pathogen

... new disruption method looks highly promising as a tool for functional genomic studies. The authors looked at over 20 genes and were able to produce transformants and inactivated genes or knock-outs in each experiment. In most cases, the efficiency of gene disruption was 100 percent, which represents a co...

Ancient ants arose 140-168 million years ago

...for biodefense and public health preparedness as a tool for rapidly detecting norovirus--a category B biot...mass spectrometry as an environmental surveillance tool for the detection of pathogenic human viruses in complex environmental samples such as human and ani...

Researchers use mass spectrometry to detect norovirus particles

...for biodefense and public health preparedness as a tool for rapidly detecting norovirus--a category B biot...mass spectrometry as an environmental surveillance tool for the detection of pathogenic human viruses in complex environmental samples such as human and ani...

Nano-particles effective in killing cancer with one-two punch of chemotherapeutics

...le drug delivery system, and should prove a useful tool in fighting a number of diseases," said Dennis Discher, a professor in Penn's School of Engineering and Applied Science and a member of Penn's newly established Institute for Translational Medicine and Therapeutics. "Here we show that drug-deliverin...

Scientists discover new genetic subtypes of common blood cancer

...y targeted to those subtypes. A new computational tool based on an algorithm designed to recognize human faces plucked the four distinguishing gene patterns out of a landscape of many DNA alterations in the myeloma genome, the researchers report in the April issue of Cancer Cell. These results "define n...

Heparin prepared synthetically could replace animal-derived drug

... version. The new process also can be applied as a tool for drug discovery, according to the researchers. ... also can be applied in solid phase synthesis as a tool for screening lead compounds with heparin-like structures for drug discovery, according to the resea...

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