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Tag: "too" at biology news

Negative effects of caffeine are stronger on daytime sleep than on nocturnal sleep

...isode." "Caffeine makes daytime sleep episodes too shallow to override the signal from the biological clock that tells the body it should be awake at this time of day," explains Dr. Carrier. "We often use coffee and other sources of caffeine during the nighttime to counteract sleepiness generated by ...

Stem cells engage in dialogue with the cells that regulate their futures

...sion results in poor maintenance of tissues, while too much can result in tumors or other malignancies. Her lab used the germline stem cell niche, found in the ovaries of fruit flies, as a model system. The production of fruit fly eggs depends on the presence of a renewable source of stem cells in the...

Uncovering DNA's 'sweet' secret

...hemical nature that (the six-carbon sugar) is just too 'bulky.' It has too many atoms," Egli said. The new insights provided by this structure lie at the heart of the most f...

Researchers seek to design first treatment for neuroAIDS

... that the virus itself secretes toxins that signal too many human nerve cells to begin programmed cell death (apoptosis), a normally healthy process where old or damaged cells chose to die and be recycled. Furthermore, nerve cells exposed to HIV may lose their ability to pass on nerve signals long before...

Lost in the labyrinth

...lov's lab have shown what happens when Wingless is too active in hematopoietic stem cells in mice. "We m...ared from the bone marrow of the mice. Others were too frequent. Bone marrow cells didn't develop into myeloid and red blood cells. B- and T-cells were als...

Weighty viruses

...ses had a margin of error of ±15%, which made them too inaccurate to ensure the resolution of small differences in mass. A team led by Huan-Cheng Chang has developed a new concept to attain higher precision. In order to determine their mass, viruses must first be converted to the gas phase, given an elec...

NHGRI aims to make DNA sequencing faster, more cost effective

...s" A nanometer is one-billionth of a meter, much too small to be seen with a conventional lab microscope. Several groups are developing nanopores (holes about 2 nanometers in diameter) for use as DNA sequence transducers and propose to detect an electrical, or ionic, signal from individual DNA molecule...

Who gives stem cells their marching orders?

... of Nodal and preventing them from differentiating too early. Using mice engineered to carry an altered form of the protein, the ISREC group showed that if this switch is blocked, Nodal has the opposite effect: it triggers a cascade of molecular signals which stimulate differentiation. In an article ap...

A buffet for early human relatives

...ine the animals' diets. Until now, lasers were too destructive to use on the smaller teeth of human ancestors and their relatives ?even those of Paranthropus, known for relatively large teeth and a strong, heavy jaw. Passey improved the laser technique. "What I did was fine-tune the method to han...

Brown scientists map structure of DNA-doctoring protein complex

...use it is a string of six proteins, the complex is too big and too flexible to analyze through standard methods such as X-ray crystallography. Sun used fluorescence...

Novel pathway regulates timing of brain cell development

...eurons are produced first, then astrocytes. Making too much of one kind of cell and too little of another at a given time could lead to brain malformations. In the October 6 issue of Cell,...

LSD treatment for alcoholism gets new look

...imately led to its demise," Dyck said. "And that's too bad, because I think the researchers in Saskatchewan, among others, showed the drug is unique and has some intriguing properties that need to be explored further." ...

New technology to speed up research into Huntington's disease

... presented with a new pair of stimuli, this proved too difficult even for the younger HD mice. Importantly, and where the screen is so valuable, all the HD mice were physically able to complete the task (i.e. they were able physically to touch the screen and obtain rewards, even though their responses...

Researchers develop technologies to devour food pathogens

...he gas must be deployed to kill the pathogens, but too much can cause a decrease of quality in the product, such as browning of leafy greens. "If the product is safe, but nobody will eat it, that's not what we want," Linton said. "We are always thinking in terms of, 'Will this work for industry?' In th...

Hopkins researchers discover how brain protein might control memory

...te to happen; the cells hyperactively swallowed up too many receptors, leaving few at the surface. Unfortunately, it's possible to over-excite a cell to death, says Worley, and if the excitation controls come off, the strength of long-term memory is altered. So what does Arc's control over brain c...

One signal elicits thousands of answers

...search for new data - which might not be necessary too soon. "Our study revealed more phosphorylation sites than all previous studies combined," says Mann. ...

Carnegie Mellon scientists use 'green' approach to transform plastics manufacturing

...h high overall levels of copper -- levels that are too costly to remove efficiently on a large-scale industrial basis. The PNAS report highlights the team's novel use of "excess reducing agents" to lower the amount of copper catalyst from 5,000 parts per million (ppm) to 10 ppm. The team showed that y...

Computer scientists unravel 'language of surgery'

... identify surgical movements that are imprecise or too time-consuming. But to get to that point, computers first must become fluent in the "language" of surgery. This will require computers to absorb data concerning the best ways to complete surgical tasks. As a first step, the researchers have begun c...

From a lowly yeast, researchers divine a clue to human disease

.... These garbled genetic messages -- whether with too much or too little genetic information -- can disrupt the normal functions of cells and, in some cases, lead to ...

Ancient ape ruled out of man's ancestral line

...f mankind, have now been shown to be 400,000 years too young to be a part of man’s family tree. The remains of the apeman, dubbed Little Foot, were discovered in a cave complex at Sterkfontein by a local South African team in 1997. Its bones preserved in sediment layers, it is the most complete hominid ...

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