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Tag: "tolerance" at biology news

Source of molecular triggers in cutaneous T cell lymphoma identified

...promoting Treg development may be useful to induce tolerance in autoimmune disease and transplantation," ...

Alcohol's effects on gene expression in the central nervous system

...sitivity to the effects of alcohol, development of tolerance to the effects of alcohol, development of alcohol dependence, and alcohol withdrawal severity," he said. "For the average reader, knowing which genetic profiles might contribute to excessive alcohol drinking could be used to identify risk factors tha...

World's largest rainforest drying experiment completes first phase

...biggest surprise noted thus far has been the great tolerance that this forest presented in the face of the severe drought that was created. As the moisture stored in the soil that sustained the forest during prolonged dry seasons was depleted in the dry plot, the trees simply absorbed water from deeper in the ...

Chemists identify immune system mechanism for methamphetamine binges

...may be able to recognize methamphetamine and boost tolerance to the drug through an unusual vaccine-like mechan...immune system recognition and a consequent rise in tolerance to the drug, Janda and his associates theorize. Tolerance refers to the capacity to have a decreased...

Genetic defects give the immune system the green light to attack the pancreas

... which researchers elsewhere had shown to have the tolerance defect, with diabetes-resistant controls. They looked for regions where the data from the DNA chips and the genome scan converged. Overlap would indicate the regions and genes that affect tolerance. In the mice with diabetes, two findings emerged ?a...

Study uncovers bacteria's worst enemy

...istance to radiation does not necessarily ensure a tolerance for radionuclides. In fact, the bacteria's worst enemy in a nuclear waste site may not be the radioactive elements, but rather, the other toxic metals that might also be found at the site. The study also shows that contrary to the conventional wisdo...

Mouse with designer liver has enhanced glucose tolerance, insulin response

...eng Feng has created a mouse with improved glucose tolerance and insulin activity in the liver, and generated n...ose load was diminished in LGKO mice, thus glucose tolerance in the liver was significantly improved in the absence of Gab1 protein. The Feng team conducted bio...

Single-donor Islet Transplantation Procedure Shows Promise For Patients With Type 1 Diabetes

...ol (as evidenced by normal results of oral glucose tolerance testing in 4 of 5 recipients with sustained insulin independence) using significantly fewer islets," the authors write. "These findings may have implications for the ongoing transition of islet transplantation from clinical investigation to routine c...

Fluorescing lab worms signal longer life spans

... protein. The brightest worms also had the highest tolerance to extended exposure to heat. "The ability to predict differences in longevity of this magnitude have never before been reported, especially given that the predictions are made on the first day of adult life," Johnson said. Obtained from jellyfish ...

Wild grasses and man-made wheats advance research capabilities

... wheat aphid, as well as the need for more drought tolerance present challenges, he said. Progress in traditional breeding has been slow due to limited genetic variability for these traits. Two projects growing in the Texas Agricultural Experiment Station greenhouses in Vernon and Bushland are designed to inc...

New type of rejection blocker protects kidneys after transplant

...nts based on this new principle of inducing immune tolerance of the transplanted organ. If belatacept and simil...expects his patients to receive an injected immune tolerance treatment a few times a year -- and perhaps to be able to stop taking anti-rejection drugs altogethe...

AIDS expert says global strategy needed to combat feminization of HIV/AIDS

...poverty, policies that deny women an education and tolerance of violence against women. The excessive biological vulnerability to HIV among young women, is believed to be due to an immature genital whose mucosal lining is easier for the virus to penetrate; to hormonal factors, such as the use of birth control...

Living with salt

...ruction. Pondering why a structure conferring salt tolerance should evolve once in a Dead Sea organism and once in a mouse has led the researchers to some new insights into kidney physiology. The researchers hope that the knowledge gleaned from their study of a tiny alga might provide the basis for designing n...

Life-extending protein keeps blood sugar in check

...rt1 in cells of the pancreas have improved glucose tolerance and enhanced insulin secretion in response to gluc...t1 in b cells of the pancreas had improved glucose tolerance and enhanced insulin secretion in response to glucose. The altered mice maintained their improved b...

Sea Ice May Be on Increase in the Antarctic

...rt1 in cells of the pancreas have improved glucose tolerance and enhanced insulin secretion in response to gluc...t1 in b cells of the pancreas had improved glucose tolerance and enhanced insulin secretion in response to glucose. The altered mice maintained their improved b...

Opiate cocktail may spare cells from morphine's dark side

... a related opioid drug, significantly reduced both tolerance and dependence in test animals. The work is repor...a signaling imbalance that is a hallmark of opiate tolerance and dependence. This suggests that the promotion of MOP-receptor internalization might prevent such ...

Global warming increases oyster sensitivity to pollution

...ll focus on to what extent cadmium reduces thermal tolerance of cold-blooded species. ...

Breast tumors in mice eradicated using cancer vaccine

...ent presents with cancer, they've developed immune tolerance to the tumor antigen, particularly when the antigen is expressed at low levels on normal tissue as with Her2/Neu," explains Paterson. "So how is the body to mount a strong enough immune reaction?" In general, bacteria are good at inducing both innat...

Women feel more pain than men, research shows

...ed by men helped increase their pain threshold and tolerance of pain, it was unlikely to have any benefit for w...t which volunteers first notice the pain) and pain tolerance (the point at which volunteers can no longer stand the pain). An upper time limit of two minutes is ...

Scientists map one of biology's critical light-sensing structures

...nococcus radiodurans, a bacterium renowned for its tolerance to ionizing radiation. It was only within the last eight years that scientists from Vierstra's and other labs discovered that, like plants, some bacteria harbor phytochromes. That finding opened the way for the Wisconsin team to define the structure ...

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