Basic research leads to a novel cancer therapy
...ling cascades are absolutely necessary, if various tissues - like blood vessels, nerve tissue, and connective tissue - are to be built up during the development of an organism and in the process of tissue regeneration. Research has focussed on these tumour cell signalling cascades, because in cancers they a...New insights into neural tube defects
...al distribution of specific proteins within neural tissues in fruit flies controls the orientation and migration of cells. Working with colleagues Brian Ciruna, Diana Lee, and Alexander Schier, who were at New York University when the research was conducted, and Andreas Jenny of Mount Sinai, Dr. Mlodzik's ...Potential heart benefit found in stem cells
...sted stem cells from the animals' subcutaneous fat tissues (ADSC, adipose derived stem cells). After repairi...tudy. "We believe that stem cells from the adipose tissues may be a valuable novel alternative source for helping support cardiac regeneration after a heart at...Paleontologists learn how not to become a fossil
...a shrimp, or they live parasitically upon the soft tissues of another organism. These guys have a lousy fossi...ng inside the tissues, or directly attached to the tissues of another organism and it dies, then you're attached to a corpse of decaying organic matter, which ...Berkeley researchers lay groundwork for cell version of DNA chip
...-screening technologies, the growing of artificial tissues and the design of neural networks. "Just as DNA chips revolutionized genome analysis, we hope to make cell chips (self-assembled arrays of cells on a thumbnail-sized chip) using our DNA-based cell adhesion strategy," said Ravi Chandra, a researcher ...Growth factor-promoting angiogenesis expressed in tumor cells and normal neurons
...he interaction between tumor cells and surrounding tissues and may have substantial significance for design of more effective therapeutics for one of the most lethal types of tumor, malignant gliomas. Stem cell factor (SCF) is an important growth factor for multiple cell types. Research has shown that SCF ...Study indicates dramatic rise in antibiotic-resistant community-acquired staph infections
...esides on skin and in noses, and typically infects tissues through cuts or rashes. Those infections can remain minor, or lead to illnesses ranging from boils or abscesses to necrotizing skin infections, pneumonia and sometimes blood stream infections. The Centers for Disease Control and Prevention (CDC) re...Molecular force field helps cancer cells defend against attack
... VEGFR-3 at dosages markedly less toxic to healthy tissues yet lethal to cancer. "We have a therapeutic window," said Cance, the study's senior investigator. "In normal cells we've shown you can knock it out and cells can still resist the loss of expression of focal adhesion kinase, whereas the tumor cells...History of human cannibalism eats away at researchers
...rotein that can abnormally fold and amass in brain tissues to cause fatal neurodegenerative diseases such as mad cow disease. These diseases are cumulatively known as transmissible spongiform encephalopathies (TSEs) and in humans, include CJD (Creutzfeldt-Jakob disease) and kuru. Kuru is confined to a hu...Engineered heart tissue offers insights into irregular heartbeats, defibrillator failure
...en induced electrical activity in these engineered tissues as would occur in ventricular tachycardia and atte...tion of electrical activity through the engineered tissues between those that responded to pace-setting shocks by halting their aberrant rhythm, and those that...Healing honey: The sweet evidence revealed
...ey stimulates growth of granulation and epithelial tissues to speed healing The review article was written by Dr. P.C. Molan of New Zealand's University Waikato. He noted that, although the many randomized controlled clinical trials strongly support the use the honey in wound care; the trials may not have b...Study finds 60 new genes controlled by DNA snippet
...g they may be involved in diseases affecting those tissues as well. In the larger picture, regulatory sequences may help to explain why humans have just 25,000 genes when, given the degree of human complexity, researchers had expected to find more than 100,000. Regulatory sequences may be part of the answ...Possible brain hormone may unlock mystery of hibernation
...sing biological interest because understanding how tissues cope with the cardiovascular and oxidative stresses associated with hibernation or torpor may have direct clinical relevance," he added. For example, he wrote, such a protective program might be exploited in transplant and vascular surgery. Scientis...Study fishes out new role for prostaglandins
...sh the three primitive layers from which all adult tissues develop ?the innermost layer (endoderm), which forms the gut and associated digestive organs; the middle layer (mesoderm), which develops into muscle, bone and cardiovascular organs, and the outer layer (ectoderm), which becomes the skin and nervous ...'Prosthetic' retinal cells let blind mice see light
...dy is that it does not involve the introduction of tissues or devices into the retina and, therefore, may largely avoid the complications of immune reactions and biocompability," wrote the researchers. "In addition, it could potentially achieve high spatial resolution for the restored 'vision' because the ap...Markers of gene, protein, or micro-RNA activity predict outcome in prostate and colorectal cancers
...an said. Hence, they then analyzed malignant colon tissues and found that there are a number of miRNAs that w...f these 16 miRNAs accurately predicted which colon tissues were normal and which cancerous. "Because this subset of miRNAs is differentially expressed at the c...AIDS-related cognitive impairment exists in two separate forms
...an said. Hence, they then analyzed malignant colon tissues and found that there are a number of miRNAs that w...f these 16 miRNAs accurately predicted which colon tissues were normal and which cancerous. "Because this subset of miRNAs is differentially expressed at the c...Albatross study shows regional differences in ocean contamination
...he environment for a long time and build up in the tissues of animals high on the food chain. Analysis of blood samples showed that concentrations of these compounds in black-footed albatrosses were 370 to 460 percent higher than in Laysan albatrosses. The two species breed at the same sites in the Hawaiia...Vegetables inhibit growth of prostate cancer in mice with human tumors
...he environment for a long time and build up in the tissues of animals high on the food chain. Analysis of blood samples showed that concentrations of these compounds in black-footed albatrosses were 370 to 460 percent higher than in Laysan albatrosses. The two species breed at the same sites in the Hawaiia......utations we've found are markers of aging in other tissues or if they are specific to tissues exposed to ultraviolet light." Either way, the newly identified biomarkers will provide another too...