Pain killer fights breast cancer by targeting key enzyme
...romatase is necessary for normal functions of many tissues in the body," Brueggemeier said. "We still have to...d. "It suggests that aromatase production in other tissues that rely on the enzyme could be spared if a nimesulide analog was taken as a drug." He said that ...Powerful new tool for studying brain development
...rative analysis of malignant and normal developing tissues provides a new method of mapping stem cells of solid tumors. The contribution of the BGEM was invaluable to our work and likely will lead to important discoveries that will improve the treatment of brain cancer." ...Rice bioengineers pioneer techniques for knee repair
...l previous attempts to grow replacement transplant tissues involved the use of biodegradable implants that ar...gineering has progressed." Unlike cartilage, most tissues in our bodies ?including skin, blood vessels and bone ?regenerate themselves constantly. Tissue engi......ive MRI scan, whether the fluid pressure in cancer tissues is at levels that could render chemotherapy ineffe...ays that, ideally, the fluid pressure inside tumor tissues would be checked using the MRI method she and her team developed before a patient begins chemotherap...Marine mammals are on the frontline of failing ocean health
...istinct chemical signals that are reflected in the tissues of fish, seals, and other killer whale food. Prey...pollutants is so distinct that it is echoed in the tissues of killer whales. Sub-populations once thought to feed mainly on salmon in Alaska are now suspected...How does the brain know what the right hand is doing?
...he brain relies on information from sensors within tissues that say how far a limb has moved. While there has been plenty of evidence that inflow plays a role, no one before has been able to show definitively that outflow is also important. Now research just published in The Journal of Physiology provides ...Nanotechnology may find disease before it starts
...ese particles to go to the mammary glands or other tissues we're interested in." The ultrasound images grew brighter over the 90-minute period. The researchers compared these images to those from a group of control mice injected with a saline solution. There was no change in ultrasound image brightness in t...New DNA 'fingerprinting' technique separates hemp from marijuana
...emically, but the drug is not present in all plant tissues or throughout a plant's life cycle. And other researchers have found that genetic markers known as "short tandem repeats," which are used to identify individuals in paternity and criminal cases, lack the power to distinguish Cannabis cultivars unequi...UCI researchers discover key factor for survival of human embryonic stem cells
...," Donovan said. "Neurotrophins help the growth of tissues in those areas and are commonly found in the nervous system. Therefore, when we use stem cells for therapy in those areas, we must be especially careful that no undifferentiated cells are transplanted where they could respond to neurotrophins and for...Darkness unveils vital metabolic fuel switch between sugar and fat
...se mice and further tests showed expression in all tissues except the brain. Injecting mice with 5'-AMP's more glamorous molecular cousins ?adenosine triphosphate (ATP), adenosine diphosphate (ADP), both vital to providing energy to cells, and the signaling molecule cyclic AMP -- did not produce the same...New hybrid virus provides targeted molecular imaging of cancer
... ability of the bacterial virus to target specific tissues with the capability of the mammalian virus to actu...unique molecular addresses. Organs and specialized tissues also have specific "zip codes" on their blood vessels, as do tumor blood vessels. Knowing this, Pasq...Gene patterns in white blood cells quickly diagnose disease
... pathogens or infectious agents in body fluids and tissues required that the pathogen proliferate to detectable and dangerous levels, thereby delaying diagnosis and treatment," says Rasha Hammamieh, a researcher on the study. Over the past five years Hammamieh and her colleagues have been studying the hos...Butterflies lose body fat during metamorphosis
...utterfly. They found that both the diet and the tissues of the larva and butterfly had a high concentration of polyunsaturated fatty acids. However, the larva had a much higher total fatty acid content than the butterfly, indicating that the transformation from larva to butterfly drastically reduced the ...Front-line immune cells mature in four stages, study shows
... Caligiuri, Freud and their collaborators analyzed tissues from more than 50 tonsils and 30 lymph nodes from the OSUCCC Tissue Procurement Shared Resource and from the National Disease Research Interchange. Through a series of experiments, they identified additional protein markers, particularly one called...Protein 'nanosprings' most resilient found in nature
...e, every time a neuron pushes its way through body tissues to its target, every time a heart beats, or a bicep muscle contracts, forces are generated. Cells have to recognize those forces and adjust accordingly." The tension created by the ankyrin springs could allow for very rapid translation of mechanical...Forsyth scientists gain greater understanding of how embryos differentiate left from right
...ding the mechanisms of signaling between cells and tissues that allows a living system to reliably generate and maintain a complex morphology. The Levin team studies these processes in the context of embryonic development and regeneration, with a particular focus on the biophysics of cell behavior. ...Alternatives to the use of nitrate as a fertiliser
...the contents of the GS and GDH enzymes in the root tissues of the different varieties of pea are increased when ammoniacal fertiliser is applied and, this increment is related to the concentration of ammonium applied. ...Avian influenza virus in mammals spreads beyond the site of infection to other organ systems
...lymph nodes. Furthermore, examination of infected tissues revealed cellular damage at sites containing viral proteins, providing an explanation for the increased severity of disease in humans. These data underscore the potential for influenza virus to spread not only from the respiratory tract but also fro...Single microRNA causes cancer in transgenic mouse
...of miRNAs in various types of normal and malignant tissues for several years. Earlier studies showed that miR155 was unusually active in some types of leukemia and lymphoma, and that its presence indicated a poorer prognosis in patients with breast and lung cancers. Croce, along with Dr. Stefan Costinean ,...Findings advance use of adult stem cells for replacement bone
...s from a patient's body and using them to grow new tissues that can be transplanted back into the patient wit...up to 75 times more calcium in the bone created by tissues in the pre-treated cultures. "To me, the most important element of the research is that it may one ...