Microscopic brain imaging in the palm of your hand
...er of a cutting-edge imaging technique to the deep tissues of the brain. By creating a handheld device based on some of the latest advances in micromotors, lensing and fiber optics (see accompanying article for more information), the researchers were able to establish a new technique that enables them to ob...VCU study shows hormone-like molecule kills cells that cause inflammation in allergic disease
...containing histamine and are present in nearly all tissues except blood. When mast cells are activated, infla... number of cytokines are rapidly released into the tissues and blood, promoting an allergic reaction. Mast cells are believed to be generated by different pr...Climate model links higher temperatures to prehistoric extinction
...containing histamine and are present in nearly all tissues except blood. When mast cells are activated, infla... number of cytokines are rapidly released into the tissues and blood, promoting an allergic reaction. Mast cells are believed to be generated by different pr...Scientists focus on 'dwarf eye'
...t give the eye its shape. During childhood, these tissues stretch, like a balloon, as the eye grows. "The RP... is believed to be the key link in signaling these tissues to stretch," said Sundin. "And MFRP, located exclusively in the RPE and nowhere else in the body, i...Missing Receptor Molecule Causes Tumor Growth
...sults were confirmed by testing 36 different tumor tissues taken directly from patients. In comparison, these...tal research. It was determined that in 20% of the tissues examined the gene responsible for DR4 was methylated to a higher degree and DR4 was missing. This r...Nanoparticles carry cancer-killing drugs into tumor cells
...sults were confirmed by testing 36 different tumor tissues taken directly from patients. In comparison, these...tal research. It was determined that in 20% of the tissues examined the gene responsible for DR4 was methylated to a higher degree and DR4 was missing. This r...Micro-molecule plays big role in birth defects
... that scientists could eliminate Dicer in specific tissues at any stage in the developmental process, thus opening a window into the role of microRNAs in limb development. In cases where Dicer is not present in developing limb tissue, Harfe showed that microRNAs were not processed and limbs were visibly sma...Investigating 'brain shrinkage' in alcoholics
...r in the brains of alcoholics. "Even after death, tissues can reveal the secrets of diseases," said Harper. "For this research, brain tissues were obtained, with ethical consent, from autopsies on alcoholic subjects. Scientists used modern mo...A novel method to measure circadian cycles
... circadian cycles in mammalian cells cultured from tissues other than the suprachiasmatic nucleus. The researchers took skin samples from humans and infected subsequently made tissue cultures with a virus engineered to report with a fluorescent signal when a certain host circadian rhythm gene was expressed....New Lab Research May Help Those Deafened By Immune System Attack
...ywire for no apparent reason, ganging up on normal tissues in our body and wreaking havoc. In thousands of people each year, the immune system attacks the inner ear, home to the tiny, delicate structures that allow us to hear. Without warning, in days or weeks, patients lose the ability to hear in one or bo...Elderly mice yield clues to the process of growing old
...at indicated accelerated cell death, especially in tissues characterized by rapid turnover of cells, occurred...fact, the team noted less oxidative stress in some tissues - the liver, for example - which suggests that accumulated genetic mutations in mitochondria slow me...Discovery of T-cell 'traffic control' boosts new drug promise
...f T cells through the blood, lymph nodes and on to tissues to fight infection -- a crucial response that sometimes goes awry, attacking the body's own tissues and causing autoimmune diseases. The traffic control system -- composed of a fat-like compound call...Study: Predatory dinosaurs had bird-like pulmonary system
...f modern birds to draw comparisons of how the soft tissues in the dinosaurs may have been structured. Birds long have fascinated biologists because of their unusual pulmonary system. Pulmonary air sacs prompt air to pass through the lungs twice during ventilation. This system also creates holes in the skele...Muscle repair: Making a good system better, faster; implications for aging, disease
...ystem may be critical for efficient repair of many tissues and for minimizing scar formation. Koh noted the following specific areas of interest: * PAI-1 levels appear to increase with aging, and may explain, in part, the loss of repair capacity as we age. Koh plans to see whether manipulating PAI-1 le...Public release of pig genomic sequences
...ibraries of expressed sequences from different pig tissues and developmental stages have been analyzed. These sequences will be released in the near future together with a publication on pig gene expression. This far, the pig sequence data have been obtained thanks to an investment of app. 10 million US$ by...‘Blue Brain?project explores thought at molecular level
...ibraries of expressed sequences from different pig tissues and developmental stages have been analyzed. These sequences will be released in the near future together with a publication on pig gene expression. This far, the pig sequence data have been obtained thanks to an investment of app. 10 million US$ by...Results of world's first gene therapy trial for arthritis show approach safe, feasible
...percentage of injected cells could escape to other tissues within one week. But with five years follow-up, the authors have seen no evidence that these genetically modified cells have caused any adverse events in their nine patients. Although the ex vivo approach did prove safe and was able to confer gene e......terns that may adversely affect the functioning of tissues and organs throughout the body for a period of several days. Importantly, the study identifies the neurotransmitter GABA (gamma-aminobutyric acid) as the link between the two clock parts that eventually pulls them back into synchronization, accordin...Discarded placentas deliver researchers promising cells similar to embryonic stem cells
...he same potential to treat diseases and regenerate tissues as their more controversial counterparts, embryoni...mnion-derived cells that are delivered directly to tissues would cause tumors, the researchers conducted studies in immune system-deficient mice and found no e......mechanisms kick in to fight them off. The infected tissues typically show depleted oxygen levels, and a protein called HIF-1 alpha regulates this. Interestingly, the cells responsible for destroying the foreign pathogens are effective in this low-oxygen environment. In a new study appearing in the July 1 pri...