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Tag: "tissues" at biology news

Young Blood Revives Aging Muscles, Stanford Researchers Find

...ral phenomenon that a person's inability to repair tissues with age-whether it's muscle, liver, skin or brain-is a matter of the regenerative cell's environment rather than the cells themselves. Rando said that finding the youth-promoting factors in the blood is no small task. "It's as big a fishing expedit...

B cells are required for development of epithelial cancer associated with chronic inflammation

...gy to protect against the development of cancer in tissues identified as "at risk" due to chronic inflammation. Previous studies have implicated an interaction between adaptive immune cells, like B lymphocytes, and innate immune cells during chronic inflammatory diseases. Dr. Lisa M. Coussens and colleagues...

Researchers Closer To Helping Hearing-Impaired Using Stem Cells

...lls to two molecules that are secreted from nearby tissues of the ear during embryonic development. The two molecules -- known as Sonic hedgehog and retinoic acid -- together caused the marrow stromal cells to further develop into cells with many of the characteristics of auditory neurons, such as the presen...

Tamoxifen-like drug suggests new ways to selectively block estrogen

...hey do, simulating the effects of estrogen in some tissues and blocking it in others. The finding indicates t...omewhere in the middle, acting like a SERM in some tissues and more like a SERD in others, including mammary tissue, where it is a powerful estrogen antagonist...

Vitamin A's paradoxical role in influencing symmetry during embryonic development revealed

...tion. Nor are they differentiated into specialized tissues -- such as heart or brain cells," he said. Once th...nces both the asymmetric arrangement of organs and tissues in the interior of our bodies and the symmetrical pattern of the exterior of the trunk. Belmonte an...

New method shows it is possible to grow bone for grafts within a patient's body

...not only for engineering bone, but for engineering tissues of any kind," adds co-author Robert S. Langer, Institute Professor at the Massachusetts Institute of Technology and a pioneer in the field of tissue engineering. "It has the potential for changing the way that tissue engineering is done in the future...

Using nanoparticles, in vivo gene therapy activates brain stem cells

...noparticles to target gene therapies for different tissues and cell types. A key advantage of the UB team's nanoparticle is its surface functionality, which allows it to be targeted to specific cells, explained Dhruba J. Bharali, Ph.D., a co-author on the paper and post-doctoral associate in the UB Departme...

Researchers grow stem cells from human skin

...e've proved that the cells can be used to engineer tissues consistent with bone, muscle and fat when implante...both in tissue engineering ?the science of growing tissues and organs in the laboratory ?as well as in cell therapy. For cell therapy, laboratory-grown cells w...

Researchers find first evidence of venom system in extinct mammal

...ter, conducting fluid from its source in glandular tissues in the upper jaw down the height of the crown to its tip," Fox explained. "When I first saw [the groove] I thought maybe it was a cavity," said Yong-Qin Sun, the lab technician who prepared the fossil, which is one of thousands that the U of A resea...

Researchers discover mechanism for multiplying adult stem cells

...ses tumors by preventing adult stem cells in these tissues from differentiating," says Hochedlinger. In other...ct4 was reactivated, the adult stem cells in those tissues continued to replicate without forming mature tissue. In a mammal's body, this type of cell behavior...

Blink, and the brain misses it

...ecause the light was bright enough to pass through tissues of the face, the fibre could be used to illuminate the retina through the roof of the mouth. Therefore, the amount of light falling on the retina remained constant, even when the volunteers blinked. The researchers then performed a type of brain scan...

Biologists determine genetic blueprint of social amoeba

...the single cells come together, differentiate into tissues and become a true multicellular organism with a fruiting body composed of a stalk with spores poised on top. This increases its utility in a variety of studies. "An organism's relationship to humans depends on how related the proteins are that are f...

New insight into autoimmune disease: Bacterial infections promote recognition of self-glycolipids

...y of the immune system to recognize the body's own tissues is essential, but sometimes the immune system loses the ability to distinguish "self" from potentially harmful invaders. This can lead to autoimmune disease characterized by destruction of healthy tissues. Although it is not clear exactly what causes...

A protein in the eye may prevent immune response and protect eyes from disease

...of the body's immune response and protect delicate tissues that cannot survive the "inflammation" inherent in full-blown immunity. "We believe that this discovery may ultimately help in the development of therapies for blinding eye diseases such as macular degeneration and autoimmune diseases that occur whe...

New tool reveals secrets of migrating cells

..."The ability to directly visualize cells in living tissues has changed the way immunologists think about how ...wing to about 200 microns, though she says in some tissues less dense than the thymus, light could penetrate nearly a millimeter - deep enough to probe cell ac...

Scientists find microRNAs regulate plant development

...cell division and cell expansion in specific plant tissues at specific stages during the plant life cycle - e.g. for leaves, roots, and floral organs to develop in the correct patterns and correct time sequence. Research reported in The Plant Cell shows that microRNAs control the accumulation of transcriptio...

New complete muscle grown in the lab

...t been as successful in thick, highly vascularized tissues such as the muscle," Levenberg says. To create muscle tissue that would be threaded through with blood vessels before being implanted, the researchers mixed different cell types together on the plastic mold for the tissue. The different cells quickl...

TGen awarded $7.1 million to accelerate brain disease research

...n about the genes turned on or off in the diseased tissues being studied. Scientists use these microarray technologies to compare genetic patterns between an individual with a disease and an unaffected person. Using this information, investigators can identify the root causes responsible for certain disorder...

Spiders help scientists discover how muscles relax

...takes advantage of a new technique for visualizing tissues in their natural state, provides new insights into the molecular basis of muscle relaxation, and perhaps its activation too. "We have solved the structure of the array of miniature motors that form our muscles and found out how they are switched of...

Scientists discover stem cell origin of neck and shoulders

...ple, the stem cell group that makes the connective tissues of the swallowing/gulping muscles also makes the skeletal regions of the shoulder girdle. This sheds new light on human diseases such as Klippel-Feil syndrome where both regions are often malformed. Dr Georgy Koentges, one of the lead researchers at...

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