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Tag: "tissues" at biology news

Programmable cells: Engineer turns bacteria into living computers

...es that detect hazards, build structures or repair tissues and organs within the body. "We are really moving...d be used to control the repair or construction of tissues within the body, possibly guiding stem cells to the locations where they are needed for the growth o...

Pulsating ultrasound enhances gene therapy for tumors

...g too hot and damaged. Pulsed-HIFU instead renders tissues permeable and helps target them for taking up genes and other therapeutic substances injected into the body. "Basically, we're using sound waves to open up the tissue by producing gaps between the cells, making it leakier and more prone to taking up...

Discovery Promises Simpler Therapy for Sickle Cell Disease

...sting blood flow according to the oxygen demand of tissues and organs, by distributing nitric oxide. Reports by the team in 2001 and 2002 further detailed nitric oxide's role in the red blood cell membrane, confirming it as the third major blood gas, along with oxygen and carbon dioxide. Those findings sugg...

Stem Cell Research Shows Potential for Replacing Tissue Damaged in Heart Attacks

...ells to replace damaged or diseased cells in adult tissues has caused extraordinary interest in their therapeutic application. Dr. Lough’s research focuses on cardiac myocytes, which are found in the myocardium tissue, or heat muscles, that helps pump the chambers of the heart. “After a patient has a heart...

Iron exporter revealed that may explain common human disorder

... 200 to 300 people in Western populations --causes tissues of the body to become overloaded with iron. Left u...intained instead through the complex regulation of tissues that transport, store, and utilize iron. Mammals, including humans, initially obtain iron from thei...

Stem cells from brain transformed to produce insulin at Stanford

...would only be able to transform into brain-related tissues such as nerves and support cells. But a group at the Salk Institute in San Diego recently published a report in which neural stem cells transformed into cells that line blood vessels - a far cry from a neuron. "That work gave us confidence that these...

New Drugs For Bad Bugs: UF Approach Could Bolster Antibiotic Arsenal

... that the difference in drug concentrations in the tissues arising from the standard form of the drug versus the sustained-release variety was so minimal, development of the new formulation was not warranted. “The company that was interested in that decided not to continue that project any more and made tha...

Computational Method Speeds Mapping of Cell Signaling Networks

...ple types of cells and their interactions, such as tissues and organs. NSF program manager Carter Kimsey thinks this study will open up a wide range of research opportunities. "There is no reason to think that this mathematical tool is for health-related fields only, there are many possible applications in ...

Researchers rein in regulatory RNAs

...e expressed at a consistent level in all cells and tissues tested, others exhibited marked tissue-specific expression patterns. Upon close examination of several SAT pairs, Abe's group found that the transcripts shared several striking characteristics. Northern blot hybridization analyses of six randomly ch...

UCSD-Salk Team Show Protein’s Gene-Silencing Role In Development of Nervous System

...in phosphatases (SCPs) are expressed in almost all tissues of the body. In their “on?position, the phosphatases prevent neuronal genes from being expressed in areas of the body, such as the heart and liver, where they shouldn’t be. When these phosphatases are shut off in the nervous system, neuronal stem cel...

Scientists identify molecule that regulates well-known tumor suppressor

...vival control mechanism is conserved among various tissues and species. Taken together, our data suggest that overexpression of DJ-1 can modulate PTEN tumor expression to the point where oncogenesis may result from upregulated PKB/Akt-mediated cell survival," writes Dr. Mak. Elevated DJ-1 levels may explain ...

Buying Time Through Hibernation on Demand

...so might extend the amount of time that organs and tissues could be preserved outside the body prior to transplantation, Roth said. Yet another potential application of oxygen deprivation would include accelerating wound healing in patients, such as diabetics, whose ability to do so is compromised. This coul...

U-M team recovers ancient whale in Egyptian desert

...so might extend the amount of time that organs and tissues could be preserved outside the body prior to transplantation, Roth said. Yet another potential application of oxygen deprivation would include accelerating wound healing in patients, such as diabetics, whose ability to do so is compromised. This coul...

Chemicals in tattoo inks need closer scrutiny

...se of MRIs, and the migration of inks to different tissues in the body, such as the lungs. It is unclear, however, what the specific causes of these reactions might be, and the only way to gain better understanding is to know what chemicals make up the inks, the researchers say. Finley-Jones and Wagner expe...

Defenseless plants arm themselves with metals

...aintain very low levels of salicylic acid in their tissues unless they are fighting an infection. Metal hyper...ave significantly elevated salicylic acid in their tissues all the time. In the current study, Salt and his colleagues compared salicylic acid levels in both ...

White Blood Cell 'Waste Disposal' System Plays Critical Regulatory Role

...s are recognized and ingested by cells in the body tissues called phagocytes. Although the specific mechanis...phils that lacked the ability to migrate into body tissues where they would have encountered phagocytes exhibited elevated IL-23 and IL-17 levels. When these m...

Genetic defects give the immune system the green light to attack the pancreas

...al for the immune system to recognize and tolerate tissues that belong in the body, which immunologists call ‘tolerance,’?said Dr. Zucchelli. “Previous studies have shown that when the T-cells don’t learn this tolerance, they can infiltrate the pancreas and attack the insulin-producing beta cells.?This first...

Study reveals new technique for fingerprinting environmental samples

...Ts) were used as diagnostic fingerprints for human tissues to determine their unique features and disease status. These information-rich data allowed researchers to forge ahead with studying genes important in disease processes, long before the completion of the entire human genome. "EGT fingerprints may be...

PET/CT can identify new cancer lesions at early stage, allowing for prompt treatment

...led view of the anatomy or structure of organs and tissues in the body. Combining PET with CT provides images showing function (PET) and anatomy (CT) and a merged or "fused" picture of the body's metabolism and structure. ...

Used in a new way, RNA interference permanently silences key breast cancer gene

...the ability of these cancer cells to invade normal tissues like the lung. "Somehow STAT3 is controlling TWIST expression, and this is important to know with regards to activated STAT3 and its involvement in cancer metastasis," Arlinghaus says. When the mouse breast cells transduced with STAT3, shRNA were th...

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