Brain tissue reveals possible genetic trigger for schizophrenia
... schizophrenia. In studying the postmortem brain tissue of adults who had been diagnosed with schizophreni...e. Using postmortem prefrontal cortical brain tissue of people with schizophrenia and persons who had no psychiatric illness, the researchers found for t...When smell cells fail they call in stem cell reserves
...ese two distinct types of stem cells in one neural tissue is a first, says Reed, who is interested to see if other types of nerves in the body have similar repair mechanisms in play. ...Breathing easy: When it comes to oxygen, a bug's life is full of it
...ult in the production of free radicals which cause tissue damage, he has said. His work could have applications to insect control in agriculture. Jake Socha, Argonne National Laboratory, Chicago, and the University of Chicago will discuss “Control of internal convection in beetles using active tracheal c...Cancer cells forming blood vessels send their copper to the edge
...model of angiogenesis and sections of breast tumor tissue rich in blood vessels. "We found that cells und... colleagues then examined sections of breast tumor tissue that were rich in newly formed blood vessels. "Once again," said Finney, "we found that in contrast ...Research project tackles 'regeneration' gap
...n living, simple organisms that sustain successful tissue and organ regeneration following injury and diseas...e systems that can then be applied to more complex tissue reconstruction needed in human organisms." Although human organ systems such as the liver are qui...Light wine intake is associated with longer life expectancy in men
... of atherosclerotic plaques ?the build-up of fatty tissue in the arteries that can result in stroke or heart attack. "Those people who already consume alcoholic beverages should do so lightly (1 to 2 glasses per day) and preferably drink wine," Streppel said. "The cardio-protective effects of alcohol and...Virginia Tech's System X supercomputer provides super tool for simulation of cell division
...relevant to the causes and treatment of cancer, to tissue regeneration, and to the control of many pathogens," Tyson said. For the budding yeast cell cycle, the experimental data consists of observed traits of 130 mutant yeast strains constructed by disabling and/or over-expressing the genes that encode ...Prion disease treatable if caught early
...in the disease. Also, studies of the animals?brain tissue revealed a parallel impairment of signaling among brain cells. However, when the researchers manipulated the animals to deplete their brains of the prion protein, their memory ability and burrowing behavior recovered. Importantly, found the resear...Stress hormones may play new role in speeding up cancer growth
...o compounds. These compounds can break down of the tissue around the tumor cells and allow the cells to more...ight have been just a laboratory aberration in the tissue cultures. "We needed to see how relevant this finding was to what happened with actual tumors," h...U of MN researchers turn cord blood into lung cells
...lture, then differentiated into different types of tissue representative of all three embryonic lineages, endoderm, mesoderm and ectoderm. In this series of experiments, McKenna and his group cultured the MLPC and differentiated it into the lung cells, an endoderm-type cell. By testing the cells that gre...Single molecule extends fat mice lives by reversing gene pathways associated with disease in obese
...terns triggered by high calorie diets. Using liver tissue of five mice at 18 months of age from each group, ...art and Liver Three pathologists examined heart tissue from the SD, HC, and HCR mice, and while not knowing which organ belonged to which mouse group, they...Gene key to taste bud development identified
...ed to ultraviolet light. "When we shine light on tissue from these animals, any cell that is expressing SOX2 will fluoresce, or light up," Pevny explained. "This allows us to directly visualize those areas where SOX2 is active. It is a very powerful tool." In their work, Hogan and her colleagues use thi...Antibiotic inhibits cancer gene activity
... other cell functions. In further experiments in tissue cultures, the researchers found that siomycin A induced cancer cells, but not normal cells, to commit suicide in a process called apoptosis. The new screening technique, Gartel said, gives researchers a rapid way to find agents that target oncogene......cardium, follow suit, invading the wounded cardiac tissue and stimulating the growth of new blood vessels. ...ng humans, are also housed inside an epicardium, a tissue about which little is known. "Scientists haven't paid much attention to the epicardium in adults,"...Cloned mice created from fully differentiated cells, a milestone in cloning research
...tem cells, which reside in a specific area of each tissue and remain quiescent until they are activated by the presence of disease or tissue injury. Yet, if this were true, Drs. Yang and Cheng point out, the results of their studies would ha...Key to zebrafish heart regeneration uncovered
...ts believe the ability to regenerate damaged heart tissue may be present in all vertebrate species, but that...d suspected that zebrafish regenerated their heart tissue by the direct division of existing cardiac muscle cells adjacent to the injury, Poss said. Howeve...Dopamine used to prompt nerve tissue to regrow
...by the neurons when used on a small piece of nerve tissue and stimulated extensive neural growth. The implanted polymer didn't cause any tissue scarring or nerve degeneration, allowing the nerve to grow in a hostile environment post injury. ...One-of-a-kind imaging probe reveals secrets useful for drug discovery
...on's or Alzheimer's disease, there is not a lot of tissue to work with, especially if you're studying a sample from a single animal. But this is a way we could obtain potentially important chemical information about disease from small amounts of brain tissue." Scientists used walking stick venom to demonst...Lungs try to repair damaged elastic fibers
...er growth, is increased in the moderately diseased tissue of COPD patients. Elastic fibers allow the lung to expand and contract with breathing. "We've found elastin synthesis to increase in the air sacs (alveoli) and airways of the lungs of patients suffering severe or end-stage COPD," Woods explained. ...Living view in animals shows how cells decide to make proteins
...ed proteins, in turn, dictate the function of each tissue or organ. The findings also may offer insight i..."Identifying which silencers are active in a given tissue or organ will ultimately help scientists understand how exons are erroneously included or excluded i...