Woven scaffolds could improve cartilage repair
... cells will grow throughout the scaffold, and over time the scaffold will slowly dissolve, leaving the new cartilage tissue" he said. "The use of this scaffold will also permit doctors to treat larger areas of cartilage damage, since the current approaches are only suitable for repairing smaller areas of ...'Guardian of the genome' protein found to underlie skin tanning
...ght, it may also underlie people's desire to spend time in the sun. The same process that causes POMC to produce alpha-MSH also leads to the production of b-endorphin, a protein that binds to the body's opiate receptors and may be associated with feelings of pleasure. "Even as p53 is causing skin to ta...It's OK for men with high blood pressure to have a drink or two, new study finds
...nd Wageningen University in the Netherlands at the time of the study and was working as a visiting scholar at the Harvard School of Public Health, which sponsors the Health Professionals Follow-Up Study. An accompanying editorial, by Victor Kipnis, PhD, at the National Cancer Institute, and others, dis...LIAI completes world's most comprehensive analysis on influenza virus data
...he H5N1 avian flu. "The database marks the first time that all known antibody and T cell epitope information has been compiled in one place," said Sette, noting the searchable online database is freely available to scientists around the globe. "It gives researchers ways of sharing knowledge and informa...RNA splicing factor implicated in ovarian tumor cell growth
... "To the best of our knowledge, this is the first time anyone has shown that interference with the production of a splicing factor can inhibit tumor cell growth and tumor invasiveness," Beck said. "Alternatively-spliced genes and splicing factors are likely to play a key role as therapeutic targets and d...Tracking sperm whales and jumbo squid
...ming together off Mexico’s Pacific coast—the first time that electronic tracking devices have been applied...predators and prey must have crossed paths at some time during the experiment, Gilly noted. "Based on the locations of where the squid tags first appeared o...Study calculates patient time costs associated with cancer care
In 2005, the overall cost of patients' time spent on cancer care was $2.3 billion in the first...he Journal of the National Cancer Institute . The time costs for the 11 cancers studied and for different phases of cancer care varied widely, they write. ...Type of stem cell found to reside in transplanted lungs
... of transplant patients demonstrates for the first time that these progenitor cells reside in adult organs...ing that they were present in the tissue since the time of transplantation. "We were able to isolate the cells derived from the donor as far as 11,5 years a...Prehistoric origins of stomach ulcers uncovered
...ted from Eastern Africa at almost exactly the same time as early humans, approximately 60,000 years ago. ...elicobacter pylori emerged from Africa at the same time as early humans it makes it easier to examine some of the controversial questions about human migrat...Scientists learn the origin of rogue B cells
...hat question, says Casellas, is one that will take time to answer. "This is only one step," he says. "We all carry these cells around, but not all of us develop autoimmunity. Our work provides one explanation for the origin of these self-reactive B cells." "If you understood the system extremely well a...Imaging techniques permit scientists to follow a day -- or four -- in the life of a cell
...s to monitor the cells under a microscope for long time periods (in excess of four days), during which the cells may divide multiple times and cycle through nearly all cellular functions. When coupled with the latest in image-analysis software, this technique allows researchers to gain a long-term perspe...Mimicking how the brain recognizes street scenes
...orse as opposed to a cow or a unicorn. At the same time the representation must be sufficiently "invariant...s. This slower form of object recognition provides time for context and reflection, such as: if I see a car, it must be on the road not in the sky. Giving t...Bacterial walls come tumbling down
... drugs that researchers design to thwart them. The time it takes for bacteria to develop resistance to new antibiotics has been as short as one year for penicillin V and as long as 30 years for vancomycin. Researchers attempting to solve the structure of this enzyme have struggled to recreate its cellu...Children who sleep more weigh less
...erage less than 10 hours. By age 14, weekday sleep time fell to 8.5 hours. “Our results suggest that many American children are not sleeping enough,?said lead researcher Emily K. Snell of the School of Education and Social Policy and the Institute for Policy Research at Northwestern University. “In add...Hotspots of mercury contamination identified in eastern North America
...n analysis of levels of mercury contamination over time in the Merrimack River watershed suggests that lowered emissions reduced mercury levels in biota within a few years. The 10-member research team was led by David C. Evers of the BioDiversity Research Institute in Gorham, Maine. The study was based ...Lithium builds gray matter in bipolar brains, UCLA study shows
... underused or dysfunctional. This is the first time researchers were able to look at specific regions of the brain that may be affected by lithium treatment in living human subjects, said Bearden. "We used a novel method for brain imaging analysis that is exquisitely sensitive to subtle difference...When your brain talks, your muscles don't always listen
...g force behind our movements," Knight said. "Every time they get a command from the neurons, the muscle fibers contract. In the generation of muscular force, the smallest controllable unit consists of an individual neuron and the muscle fibers it stimulates. We believe that our research is very important ...3-D ultrasound identifies women at risk for impending preterm birth
...gest that examining the fetal adrenal gland at the time a woman is evaluated for symptoms of preterm labor...b/Gyn. The authors said that understanding the time when a marker becomes positive in relationship to preterm birth is essential for a test with high di...Misclassified for centuries, medicinal leeches found to be 3 distinct species
...t legal and commercial implications." Since the time of Hippocrates and long before Carolus Linnaeus first described Hirudo medicinalis in 1758, medicinal leeches have been used in a variety of medical treatments--some legitimate, many not. Demand for leeches in 19th-century Europe grew so intense that...Stem cells act through multiple mechanisms to benefit mice with neurodegenerative disease
...e. When stem cells were implanted -- at simply one time point -- into brains of newborn Sandhoff mice, the... with clinical use and demonstrating for the first time that such preparations are consistent with a therapeutic impact. Sandhoff results from a genet...