Extra-aggressive form of idiopathic pulmonary fibrosis identified
...t that physicians should pay more attention to the time of onset of symptoms, and to look for other signs that allow the identification of these rapid progressor patients". In this study the authors performed global gene expression analysis and other molecular studies in a subset of patients and ident...Gene expression patterns predict rapid decline in idiopathic pulmonary fibrosis patients
...s that physicians should pay more attention to the time of onset of symptoms in their patients," Dr. Selman said. "Although preliminary, these results may allow investigators to identify biomarkers of disease progression and, more importantly, better evaluate the effectiveness of potential therapies," ...Want to save polar bears? Follow the ice
...re may be there for increasingly longer periods of time without food as the sea ice becomes more distant and inaccessible. The main question for conservationists is which of the existing 18 populations of polar bears occurring on two continents and one sub-continent stand the best chance of surviving ...Mule deer moms rescue other fawns
...fspring, even though this means the female invests time and energy and puts herself at risk by helping many other animals. In contrast, a whitetail mother waits to assess whether a fawn is her own before she steps in to defend it. As a result, whitetail fawns suffer considerably more predation during the ...'Virtual Patient' to simulate real-time organ motions for radiation therapy
...xisting 3-D models, adding the fourth dimension of time could significantly improve the accuracy and effec...could allow doctors to spot the small fractions of time when the lungs, liver, kidneys, and eventually the heart, are stationary relative to the external ra...HIVMA opposes The Gambia's unproven AIDS remedy
...meh is giving people false hope, while at the same time making them stop treatment that has been demonstrated to save lives." "Any treatment that claims to alleviate this devastating disease must be subjected to rigorous scientific scrutiny," he added. "A growing body of evidence from Africa shows the ...Arctic ice retreating more quickly than computer models project
... earlier than the IPCC- projected timeframe of any time from 2050 to well beyond 2100. The authors speculate that the computer models may fail to capture the full impact of increased carbon dioxide and other greenhouse gases in the atmosphere. Whereas the models indicate that about half of the ice loss...Resistant HIV quickly hides in infants' cells
...tance, but levels of resistant virus declined over time to undetectable levels. In the current study, however, researchers found these resistant viruses quickly took up residence in inactive T cells, from where they could later launch an attack that NNRTIs could not stop. The news was not all bad: a diff...Statin treatment improves spatial memory in mouse models of Alzheimer's
...rmal mice on statin also showed improvement in the time they usually take to reach the platform compared to normal mice on saline. After the maze test, brain tissue then was studied to determine levels of nNOS....Mice with a migraine show signs of brain damage
...ergaard’s team linked the phenomenon for the first time to both severe hypoxia and to damage to brain cell...prevention,?said Nedergaard, who notes that by the time a person feels pain or notices a visual disturbance, the changes to the brain are already well under...Machine preservation may promote more organ sharing
...vation times can be safely extended to permit more time for sharing organs across the country," said Rober...idneys were out of the body for a longer period of time (a mean of 24 hours versus 19 hours for the cold stored organs), both groups of recipients had simil...'Personality-gene' makes songbirds curious
... one behavioural test, the biologists measured the time until a bird had visited four artificial "trees" (see figure 1) after being released in the observation room. In a second test, they quantified the reaction of the bird towards each of two unknown objects that had been put in its cage. One such novel...Scripps research team sheds light on long-sought cold sensation gene
... formalin injection when compared to the amount of time control mice spent flicking and licking their paws when placed on a room temperature plate. In contrast, TRPM8-deficient mice did not receive any acute pain relief from the cold plate suggesting that cold activation of TRPM8 can mediate some of the a...Technique monitors thousands of molecules simultaneously
... tools available," he said. "But now for the first time it's not just a matter of structure, but rather a matter of location and scale ?a logistical problem." He offered the Great Wall of China as an example of a classic logistics problem ?the structure itself was simple, but getting the tools and manpo...'Insulator' helps silence genes in dormant herpes virus
...y issue of the Journal of Virology, mark the first time an insulator has been identified in a virus and may lead to ways to develop strategies to manipulate the virus. Insulators, also known as boundary elements, are DNA segments that work to prevent a gene from being influenced by the activation or r...Gene malfunctions cause schizophrenia, depression symptoms in mice
Researchers have demonstrated for the first time that malfunction of a gene that had been associated with schizophrenia and depression does indeed cause symptoms of those disorders. They said their findings in mice offer a possible animal model for developing treatments for schizophrenia and depres...Amphibians in losing race with environmental change
...r hundreds of millions of years - since before the time of the dinosaurs and through many climatic regimes - the massive, worldwide decline of amphibians can best be understood by their inability to keep pace with the current rate of global change, a new study suggests. The basic constraints of evolutio...Climate change impacts stream life
... School of Biosciences, has examined for the first time the effects of climate change on stream species. The study looked at the effects of climate change on stream macroinvertebrates - animals that can be seen with the naked eye such as crustaceans, snails and larval insects including stoneflies or......eral months to simulate a few milliseconds of real time in the brain. They show how conduction along such thin axons is affected by the probabilistic nature of voltage-gated ion channels (channel noise). Channel noise destroys information in the AP, and they conclude that these effects are much larger tha...Novel system developed to turn data into real-time, interactive 3-D images
...and allows accurate diagnosis in a fraction of the time that physicians must now spend using current image viewing technologies," Clements says. The technology can be applied to any large 3- or 4-D data set but is most readily applicable to medical images. For instance, CT scans generate large 3- and...